Alcon Ag · SIX:ALC

Alcon — Investor Day (March 2025)

88 slides from Alcon's investor day presentation, Mar 27, 2025

  1. Slide 1: Capital Markets Day

    Capital Markets Day March 27th, 2025

  2. Slide 2: Welcome

    Welcome Dan Cravens Vice President, Investor Relations

  3. Slide 3: Agenda

    14:00 CET | 08:00 CT Dan Cravens Introduction, Housekeeping & Safe Harbor David Endicott Leading in Eye Care Tim Stonesifer Financial Outlook & Expectations Q&A Session 15:00 CET | 09:00 CT Break Agenda 15:30 CET | 09:30 CT Sean Clark Leading in Ophthalmic Surgery Max Wolf Leading in Contact Lenses

  4. Slide 4: Safe harbor

    Safe harbor Forward-looking statements This press release contains, and our officers and representatives may from time to time make, certain “forward-looking statements” within the meaning of the safe harbor provisions of the US Private Securities Litigation Reform Act of 1995. Forward-looking state

  5. Slide 5: Leading in Eye Care

    Leading in Eye Care David J. Endicott Chief Executive Officer

  6. Slide 6: Alcon plays in resilient markets, underpinned by durable megatrends

    Aging Population By 2050, more than 2 billion people will be over age 601 Increasing Wealth The middle class will grow by ~1.7 billion people in 10-15 years2 Increasing Myopia plays in resilient An estimated 50% of the world will be myopic by 20503 markets, underpinned by durable megatrends New Tech

  7. Slide 7: The need for eye care is significant and largely unmet

    The need for eye care is significant and largely unmet 157 million 1.8 billion 1.6 billion with moderate-to- have live with severe uncorrected presbyopia3 dry eyes4 refractive errors2 90% of visual impairment $100B ~ could be saved with is preventable or appropriate eye care curable1 services1 65 mi

  8. Slide 8: Eye care is a large and growing market

    Eye care is a large and growing market 2024 Industry Sales1 ($B) 2024-2029E Industry CAGR Total Market $35B Mid-single digits Implantables2 $4 ~6% Surgical Consumables2 $6 $13B ~5% Equipment / Other2 $3 ~7% Contact Lenses $11 ~5% Vision Care $22B Ocular Health3 $11 ~4% 8

  9. Slide 9: Alcon strategy

    Alcon strategy Attract, develop and retain experts in eye care customers and technology Reinvest in R&D Leverage expertise We focus on eye care and product to invent or acquire development innovative products We create value by applying specialty market knowledge and specialty technical knowledge to

  10. Slide 10: We are specialists who lead the world in eye care innovation

    We are specialists who lead the world in eye care innovation ~5B+ 90+ Active projects R&D investment as of 2024 since 2018 20 8% – 10% of sales BD&L 1,900+ invested in R&D transactions each year in 2024 R&D associates in 2024 10

  11. Slide 11: Accelerating innovation in Surgical to meet growing eye care needs

    Accelerating innovation in Surgical to meet growing eye care needs 2021 – 2024 2025 – 2026 NEXT-GEN PHACO-VIT & CONSUMABLES CLAREON PANOPTIX PRO DSLT – GLAUCOMA NEXT-GEN DIAGNOSTIC 11

  12. Slide 12: Accelerating innovation in Vision Care to meet growing eye care needs

    Accelerating innovation in Vision Care to meet growing eye care needs 2021 – 2024 2025 – 2026 for Astigmatism Sphere Complete, Ultra and Hydration MDPF Sphere, for Astigmatism, Multifocal AR-15512 Multifocal Toric (Acoltremon, Dry Eye) 12

  13. Slide 13: Accelerating innovation drove accelerated sales growth

    Accelerating innovation drove accelerated sales growth Net sales growth (year-over-year, shown in constant currency1) 12% 11% 10% 6% 5% 5% 3% 2017 2018 2019 2021 vs. 2019 2022 2023 2024 Faster sales growth Sales growth of low-to-mid single digits pre-spin has accelerated, driven by innovation 13

  14. Slide 14: Faster sales growth drove earnings expansion

    Faster sales growth drove earnings expansion Core net income constant currency growth1 34% 23% 17% 16% 8% 2% Earnings expansion 1% Meaningful earnings expansion since spin, driven 2017 2018 2019 2021 vs. 2019 2022 2023 2024 mainly by operating leverage from accelerating sales growth 14

  15. Slide 15: Then versus Now: Alcon in 2019 vs. 2024

    Then versus Now: Alcon in 2019 vs. 2024 $7.4B $9.8B Sales Sales 38.1% 33.0% Core SG&A1 as a % of sales Core SG&A1 as a % of sales 7.9% Core R&D1 as a % of sales 2019 2024 8.8% Core R&D1 as a % of sales 17.2% 20.6% Core operating margin1 Core operating margin1 $367M $1.6B Free cash flow1 generation F

  16. Slide 16: Building on our momentum

    THE NEXT FIVE YEARS Building on our momentum Maintain momentum in Surgical and Vision Care portfolios while accelerating R&D productivity Create world-class efficiency through a digital enterprise Make select bets in digital health and pharma Create world-class product development and commercializat

  17. Slide 17: Alcon Acquires Majority Interest in Aurion Biotech

    AURN001 is an investigational product and has In the Press: Alcon Acquires not been submitted to US FDA for approval Majority Interest in Aurion Biotech, Inc. AURN001 is an innovative allogeneic cell therapy consisting of corneal endothelial cells and a rho kinase inhibitor • A leading cause of visi

  18. Slide 18: A purpose-driven organization, dedicated to helping the world See Brilliantly

    A purpose-driven organization, dedicated to helping the world See Brilliantly

  19. Slide 19: Financial Outlook

    Financial Outlook Tim Stonesifer Chief Financial Officer

  20. Slide 20: Framework for shareholder returns

    Durable top-line growth underpinned by resilient and growing markets Framework for Balanced geographic footprint and innovative product portfolio shareholder returns Earnings growth from operating leverage while prioritizing R&D investments Significant cash flow generation to support capital allocat

  21. Slide 21: Above-market sales growth and operating leverage with step-change in Free Cash Flow

    We’ve delivered above-market sales growth and operating leverage with step-change in Free Cash Flow during 2024 Net Sales Core Operating Income1 Free Cash Flow1 $B $B $B % of Net Sales 3Y CAGR 3Y CAGR 3Y CAGR +10% cc1 24% cc1 35% USD $9.8 $2.0 $1.6 $9.4 $1.8 $8.7 $8.2 $1.6 $1.4 $7.4 $1.3 $0.7 $0.6 $

  22. Slide 22: We're ahead of the goals outlined at CMD21 for 2025

    We’re ahead1 of the goals outlined at CMD21 for 2025 2025 from CMD21 2025 Guidance3,6 2025 Adjusted4,6 Net Sales ~$10B $10.2B - $10.4B $10.8B - $11.0B Core Operating Approaching 21% - 22% 24% - 25% Margin2 (%) mid-20s Free Cash Flow2 ~$1.8B - $2.0B On track5 22

  23. Slide 23: Long-Term Outlook Assumptions

    Long-Term Outlook Assumptions Outlook assumes: • Markets grow at mid-single digits on average (historical rates) • Innovation drives above-market growth for Alcon • Core R&D1 at 8% to 10% of net sales to accelerate product flow • Continued operating leverage • Core effective tax rate2 of ~20% • Cape

  24. Slide 24: Our long-term financial goals position us well for sustainable shareholder returns

    Our long-term financial goals position us well for sustainable shareholder returns Net Sales Core diluted Free Cash Flow Durable top-line growth Growth EPS Growth1 Conversion1,2 Earnings growth +6% - 8% +12% - 15% in constant in constant 90%+ currency1 currency1 Free Cash Flow Generation 24

  25. Slide 25: Resilient markets and innovative product portfolio support above-market growth

    Resilient markets and innovative product portfolio support our above-market growth goals Net Sales $B, % CAGR1 Surgical Innovation Highlights Equipment: UNITY suite Consumables: Procedure value Implantables: Penetration & next-gen IOLs $9.8 Vision Care Innovation Highlights Contact Lenses: Portfolio

  26. Slide 26: Profitability expansion from operating leverage while prioritizing R&D

    Profitability expansion from operating leverage while prioritizing R&D investments Core Functional Costs Core R&D1 Drivers of Continued Margin Expansion % of Net Sales Core SG&A1 46% 8% 42% End-to-end process optimization 9% Digital enterprise efficiencies 38% 33% Capitalizing on shared service foot

  27. Slide 27: Capital allocation priorities remain consistent

    Capital allocation priorities remain consistent Invest in Invest in Return to organic growth BD&L and M&A shareholders • R&D investment • Agnostic to the source of • Payout policy of 10% of • New product launches innovation Core Net Income1,2 • Capacity expansion • Bolt-on acquisitions and • Share r

  28. Slide 28: Framework for shareholder returns

    Durable top-line growth underpinned by resilient and growing markets Framework for Balanced geographic footprint and innovative product portfolio shareholder returns Earnings growth from operating leverage while prioritizing R&D investments Significant cash flow generation to support capital allocat

  29. Slide 29: Leading in Ophthalmic Surgery

    Leading in Ophthalmic Surgery Sean Clark General Manager, Surgical

  30. Slide 30: Surgical | Overall market

    Surgical | Overall market Leading in a strong global surgical market 2024 Global Surgical Sales 2024 Industry Sales Industry CAGR $B $B %, 2024-2029E Implantables 4 ~6% Others $5.5 ~$13B Consumables 6 ~5% market Equipment/ Other 3 ~7% Total 13 ~6% 30

  31. Slide 31: Surgical | Alcon portfolio

    Surgical | Alcon portfolio Driving growth across three categories Implantables Consumables Equipment/Other $1.8B Alcon sales (2024) $2.9B Alcon sales (2024) $0.9B Alcon sales (2024) Figures are rounded. 31

  32. Slide 32: Surgical | Equipment, consumables & connected ecosystem

    Surgical | Equipment, consumables & connected ecosystem Equipment and consumables: a key driver of growth in the Sx portfolio UNITY VCS/CS console UNITY consumables Connected ecosystem Operating Room (OR) anchor with best-in- Next-generation single-use New and connected diagnostic, microscope class

  33. Slide 33: Equipment | Next-gen vit-cataract system

    Equipment | Next-gen vit-cataract system Superior efficiency in a dual-function console to drive upgrades and capture share Today Pipeline: UNITY VCS/CS SUPERIOR EFFICIENCY1 Designed to safely improve OR throughput Up to 2X faster phaco with 40% less energy from UNITY 4D Phaco 1.5X faster vitreous c

  34. Slide 34: Equipment | UNITY VCS/CS comparison vs. CENTURION

    Equipment | UNITY VCS/CS comparison vs. CENTURION UNITY 4D Phaco is twice as fast as CENTURION Ozil 4D Phaco Phacoemulsification vs. Ozil Phacoemulsification on the bench 34

  35. Slide 35: Consumables | Next-gen UNITY consumables

    Consumables | Next-gen UNITY consumables Designed to increase operating room efficiency and improve user experience UNITY Cataract UNITY Vitrectomy Consumables Consumables Premium cassette with balanced tip to power Premium cassette with a less invasive 4D phaco for a more efficient surgery 27-gauge

  36. Slide 36: UNITY VCS/CS driving value creation for ECPs and Alcon

    UNITY VCS/CS driving value creation for ECPs and Alcon Installed base conversion to drive growth for Alcon’s cataract and vit-ret businesses over the next 10 years Procedures per year, cases1,2 Legacy (CENTURION/CONSTELLATION) and UNITY VCS/CS sales, $m +200 +150 4,000 4,200 900 1,050 Vitret Catarac

  37. Slide 37: Connected ecosystem | Adi & next-gen equipment

    Connected ecosystem | Adi & next-gen equipment Building holistic digital experiences with a robust equipment pipeline to enhance customer value Alcon’s cataract equipment ecosystem Clinic Operating Room EQUIPMENT Sx Planner ECOSYSTEM: Clinical decision support and remote planning for UNITY M ~$1b ca

  38. Slide 38: Equipment | LENSAR acquisition

    Equipment | LENSAR acquisition Strengthening Alcon’s cataract equipment and technology portfolio ALLY Strategic rationale Deal terms International expansion $14 per share (with additional of ALLY’s technology contingent value of $2.75)1 Complements Alcon’s Total acquisition value cataract portfolio

  39. Slide 39: Surgical | IOL portfolio

    Surgical | IOL portfolio Near-to-medium portfolio launches span across PCIOLs, toric and monofocal 2025 Medium term New New New extended trifocal monofocal+/mono toric+ depth-of-focus IOL New monofocal+ New EDoF IOL Coming Coming soon soon Reduce visual disturbances Enhanced intermediate More depth

  40. Slide 40: PanOptix Pro | Next-gen trifocal

    PanOptix Pro | Next-gen trifocal The Power of Pro – more light, less scatter Most light utilization Designed for: in a trifocal IOL • 50% less light scatter Light distribution comparison vs PanOptix • 16% better image contrast and smoother transition between distance and intermediate *Simulated phot

  41. Slide 41: IOL portfolio | ATIOL penetration impact

    IOL portfolio | ATIOL penetration impact Continued gains in ATIOL penetration in international markets driving growth Global ATIOL penetration, % of foldable units Est. penetration potential1 Significant opportunity to increase ATIOL penetration ~40% Long-term macro trends expected to 15.2% underpin

  42. Slide 42: Our glaucoma portfolio covers implantables, equipment & consumables

    Our glaucoma portfolio covers implantables, equipment & consumables Shifting the treatment paradigm from pharma to laser-first with DSLT Disease Mild-to-moderate Mild-to-moderate Severe progression Early stage Pharma Surgical cataract combo Surgical Est. US procedures 600K 6,500K1 250K 100K Alcon’s

  43. Slide 43: Expanding the SLT category: VOYAGER DSLT

    Expanding the SLT category: VOYAGER DSLT First-in-line for treatment of glaucoma VOYAGER DSLT Business model Launch timeline Existing Received US FDA 510k reimbursement clearance in Dec 2023 Recurring revenue of Launched with direct sales >80% in steady state force in select EU markets High-margin F

  44. Slide 44: Summary Surgical

    Most comprehensive pipeline to continue growing faster than competition: Upcoming equipment launches across Surgical portfolio driving growth, bolstered by value capture through premium consumables tied to new equipment Summary Maintain ATIOL leadership with solid pipeline to expand market share and

  45. Slide 45: Leading in Contact Lenses

    Leading in Contact Lenses Max Wolf General Manager, Contact Lenses

  46. Slide 46: Vision Care | Overall market

    Vision Care | Overall market Large market that continues to grow at ~4% overall, Alcon has a strong position 2024 Global Vision Care Sales1 2024 Industry Sales Industry CAGR $B $B %, 2024-2029E Others ~$4.3 Contact Lens 11 ~5% OTC Pharma ~$22B market Ocular Health 7 4 ~4% Vision Care 22 ~4% 46

  47. Slide 47: Contact lens | Market dynamics

    Contact lens | Market dynamics Two dynamics driving contact lens market growth: Specialty lenses and a shift towards Daily Disposables Retail Market by Type Unit Market by Modality Retail Market by Modality USD as defined by monthly EQ (MEQ)1 USD 6% CAGR 3% CAGR 6% CAGR (2020 – 2024) (2020 – 2024) (

  48. Slide 48: Contact lens | Recent performance

    Contact lens | Recent performance We have consistently outperformed the market driven by our innovation ALC global contact lens retail market share evolution1 (2020-2024, GfK data) Cumulative Growth vs. Market (GfK data, indexed to 2022 and Alcon 2020) 2-Year Performance +210 basis points2 ~26%3 Alc

  49. Slide 49: Contact lens | Short-term focus areas

    Contact lens | Short-term focus areas Continue to drive growth with innovative product portfolio 1 2 Building the most innovative Continue to win in product portfolio Specialty lenses 49

  50. Slide 50: Building most innovative contact lens portfolio

    1 Building most innovative contact lens portfolio Sizable market share opportunity in Reusables segment 2024 sell-in by modality1 Leading Alcon products Alcon retail share2 % Premium Segment Mainstream Segment ~$11B ~29% Daily Dailies Disposable ~61% 1 point of share: ~ $65M revenue ~25% Reusables M

  51. Slide 51: Introducing a new, weekly modality: PRECISION7

    1 Introducing a new, weekly modality: PRECISION7 Start and end every week fresh ACTIV-FLO System Fresh new lens every week Featuring the ACTIV-FLO System Superior comfort PRECISION7 Even when looking at digital devices Start and end every week fresh 1.2 (vs. ACUVUE OASYS^ 2-week**, at the The new 1-

  52. Slide 52: PRECISION7

    1 PRECISION7 Strong positive reactions to PRECISION7 from customers and wearers NOVEL INNOVATION PRECISION7 Sphere and PRECISION7 Toric 52

  53. Slide 53: Winning in specialty lenses

    2 Winning in specialty lenses Alcon innovation driving outstanding share growth with additional opportunities ahead of us ALC global Toric market share evolution1 (2020-2024, GfK data) Next Toric launches Launching now ~22% ~700 basis points of share growth 2 ~22%3 TOTAL30 ~15% Toric launch Future l

  54. Slide 54: Summary Contact Lens

    Well-positioned to continue to grow ahead of market: Building the most innovative portfolio of high-performance lenses Summary Contact Lens Creating a new one-week segment with PRECISION7 to gain fair share in the reusable segment Winning in biggest and fast-growing specialty segment of toric lenses

  55. Slide 55: Leading in Ocular Health

    Leading in Ocular Health Jonathan Balch General Manager, Ocular Health & Pharmaceuticals

  56. Slide 56: Ocular Health & Pharma | Portfolio and market opportunity

    Ocular Health & Pharma | Portfolio and market opportunity Drive growth through continuous innovation 2024 Global Ocular Health & Pharma Sales Artificial Tears Allergy Market Size Market CAGR 2024 ’24-’29 ~$11B market ~4% market growth Other OH OTC1 $1.2B +0.5% Allergy $0.7B +5% Contact Lens Care $1.

  57. Slide 57: Ocular Health & Pharma | Focus areas

    Ocular Health & Pharma | Focus areas Our near-term focus areas seek a path to sustainable growth 1 2 3 Drive Accelerate Launch SYSTANE Growth Pharma Re-Entry Novel Dry Eye Rx 57

  58. Slide 58: Ocular Health | SYSTANE PF growth opportunity

    1 Ocular Health | SYSTANE PF growth opportunity SYSTANE growing double digits around the world with long runway ahead for MDPF 2024 (growth in cc1) North America Europe Asia Pacific MDPF MDPF MDPF 29% 20% 69% North America market Latin America International market3 UDPF Global Preserved UDPF 20% 22%

  59. Slide 59: Ocular Health | Alcon's longest lasting artificial tear

    1 Ocular Health | Alcon’s longest lasting artificial tear SYSTANE Pro PF: The only MDPF triple-action formulation: launched 1Q ‘25 10+ Hours of Symptom Relief Triple Action Dry Eye Relief with Hyaluronate (HA) Hydrates, Restores & Protects for All Types of Dry Eye 86% 81% Doctor intent to Consumer i

  60. Slide 60: Pharmaceuticals | Accelerating growth

    2 Pharmaceuticals | Accelerating growth Strategic intent to re-establish Alcon as an industry leader Right to Win Progress to Date Fragmented Market: Many assets <$1B - Portfolio too small for “Big Pharma” Build: Targeted Investments R&D • At Scale Pharma R&D Natural Aggregator: Largest & best Build

  61. Slide 61: Pharmaceuticals | Accelerating growth

    2 Pharmaceuticals | Accelerating growth We continue to build our pharma pipeline focusing on promising and large categories Glaucoma Rocklatan LCM (~$2.9B market) We continue to look for: • Internal opportunities to: acoltremon LCM acoltremon o Reformulate or repurpose Dry Eye (~$1.4B market) (AR-15

  62. Slide 62: Unmet Needs in Dry Eye | Speed & Efficacy

    3 Unmet Needs in Dry Eye | Speed & Efficacy Patients report limitations of existing Dry Eye prescription medications Top Priorities for Dry Eye Patients Report Dry Eye Patients* Discontinuation rates of ~90% § Time to onset 60% of patients reported mild to no improvement ‡ ONLY 13% Treatment effecti

  63. Slide 63: acoltremon | Novel Dry Eye Rx

    acoltremon ophthalmic solution 0.003% is an investigational product Pharmaceuticals | Novel Dry Eye Rx and is pending US FDA approval 3 Acoltremon 0.003% is the only eye drop that rapidly increases natural tears: PDUFA Date – May 30th Phase 3 Clinical Trial Findings* Delivers rapid onset as early as

  64. Slide 64: Introducing Acoltremon

    acoltremon ophthalmic solution 0.003% is an investigational product Introducing Acoltremon and is pending US FDA approval 3 Acoltremon ophthalmic solution 0.003% 64

  65. Slide 65: Pharmaceuticals | Phase 3 pooled data

    acoltremon ophthalmic solution 0.003% is an investigational product and is pending US FDA approval 3 Pharmaceuticals | Phase 3 pooled data COMET data supports path to full indication of “treatment of signs & symptoms of DED” COMET-2 + COMET-3: COMET-2 + COMET-3: Proportion with ≥10 mm Increase in Ch

  66. Slide 66: Summary Ocular Health & Pharmaceuticals

    Drive continued SYSTANE revenue growth through strong commercial execution against MDPF formulations Summary and the launch of SYSTANE PRO PF Ocular Health & Execute a world-class launch of acoltremon 0.003%, Pharmaceuticals first-in-class Dry Eye Rx Accelerate Alcon’s re-entry into pharmaceuticals

  67. Slide 67: Innovating for the Future

    Innovating for the Future Jeannette Bankes SVP, President, Global Franchises

  68. Slide 68: Innovation | Long-term focus areas

    Innovation | Long-term focus areas Combining technical expertise across surgical and vision care domains Surgical Vision Care 1 2 3 4 5 Next-Gen Next-Gen Lasers, Specialty Contact Next-gen Artificial Rx ATIOLs Robotics Lenses – Next-Gen Tear (OTC) Pharma Presbyopia 68

  69. Slide 69: Long-term innovation | Pushing the limits of PanOptix and Vivity

    1 Long-term innovation | Pushing the limits of PanOptix and Vivity Pushing the limits of traditional trifocal and EDoF to converge on PCIOL performance ceiling Presbyopia correction tradeoffs Visual disturbances Competitors’ EDoF lenses The end goal: Competitors’ trifocal lenses Converge performance

  70. Slide 70: Long-term innovation | Accommodating IOL program

    1 Long-term innovation | Accommodating IOL program Our program is the only one to achieve 1 diopter of accommodation and 2 diopter of tunability Accommodating IOL MOA 70

  71. Slide 71: Long-term innovation | Accommodating IOL program

    1 Long-term innovation | Accommodating IOL program Only accommodating IOL program with true accommodation and tunability Where we stand Robust clinical data proving objective accommodation, >1.5D on average Tunability demonstrated on bench, up to 2 diopters of sphere adjustment Next steps: Scalabili

  72. Slide 72: Long-term innovation | Surgical long-term investments

    2 Long-term innovation | Surgical long-term investments Long-term surgical investments, focusing on lasers and robotics Retinal Diseases Refractive Glaucoma Cataract – Laser Cataract – Other Description Treatment for Laser for All-in-one laser Precision laser Laser-based Robotics for dry AMD floater

  73. Slide 73: Flexibility in Contact Lens manufacturing asset base

    3 Flexibility in Contact Lens manufacturing asset base Unparalleled manufacturing flexibility enables strategic competitive advantages to innovate Manufacturing Flexibility Breakthrough Innovation Improved Utilization Output (OEE): Actual Target Y1 Y2 Y3 Y4 Y5 • High flexibility for all Alcon chemis

  74. Slide 74: Specialty contact lenses: Next-gen presbyopia

    3 Specialty contact lenses: Next-gen presbyopia We have unparalleled optical design capabilities to leverage for a better presbyopia solution Current Limitations of Multifocal Leveraging Alcon SX Optical Contact Lenses Design Capabilities Insufficient visual outcomes Current near (high ADD) Positive

  75. Slide 75: Next-gen tear film therapy

    4 Next-gen tear film therapy Next phase of innovation for artificial tears targeting the mucin layer (the foundation of healthy tears) Illustration1 Dry Eye Tear Film Unmet Need Tear Film Thickness2 Lipid Layer • Today’s artificial tears do not address the tear film foundation (mucin layer) • Longer

  76. Slide 76: Sustained Drug Delivery for Wet AMD

    5 Sustained Drug Delivery for Wet AMD PRINT technology for sustained release of Axitinib for durable treatment of Wet AMD Wet AMD PRINT Technology Unmet Need Bio-erodible PRINT Implant • Current wet AMD treatments require injections every 4-16 weeks • Significant patient treatment burden Applicator

  77. Slide 77: Aurion: Product overview & opportunity

    AURN001 is an investigational product and has Aurion: Product overview & opportunity not been submitted to US FDA for approval 5 AURN001 has received Breakthrough Therapy and Regenerative Medicine Advanced Therapy designations from the FDA Corneal Endothelial Disease affects the innermost layer of t

  78. Slide 78: Summary Long-Term Innovation

    Rich pipeline of early-stage innovation driving our future growth potential Innovation Capacity: World-class technical capability, knowledge estate and understanding of eye care needs Summary Surgical: • Implantables: Advancing disruptive IOL technologies to Long-Term be first to market • Equipment:

  79. Slide 79: Conclusion & Thank You

    Alcon Conclusion & Thank You

  80. Slide 80: Appendix

    Appendix 80

  81. Slide 81: Non-IFRS financial measures

    Non-IFRS financial measures Alcon uses certain non-IFRS metrics when measuring performance, including when measuring current period results against prior periods, including core results, percentage changes measured in constant currencies, compound annual growth rates, free cash flow and free cash fl

  82. Slide 82: Non-IFRS financial measures

    Non-IFRS financial measures Constant currencies Changes in the relative values of non-US currencies to the US dollar can affect Alcon’s financial results and financial position. To provide additional information that may be useful to investors, including changes in sales volume, we present informati

  83. Slide 83: Non-IFRS financial measures

    Non-IFRS financial measures 2025 Estimates translated at 2021 average exchange rates and adjusted for M&A impacts on sales Guidance for 2025 translated at the average exchange rates of 2021 and excluding impacts on Net Sales of M&A not yet executed at the time of the 2021 CMD presentation (March 202

  84. Slide 84: Reconciliation of IFRS results to Core results

    Reconciliation of IFRS results to Core results Amortization of certain intangible Separation Core as a % of (1) (2) (3) (4) ($ millions, except %) IFRS Results % of Net sales assets Impairments costs Other items Core results Net sales 2019 Net sales 7,362 - - - - 7,362 Research & development (656) 8

  85. Slide 85: Reconciliation of IFRS results to Core results

    Reconciliation of IFRS results to Core results ($ millions, except %) 2019 % of sales 2021 % of sales 2022 % of sales 2023 % of sales 2024 % of sales Net sales 7,362 8,222 8,654 9,370 9,836 Operating (loss)/income and margin (187) (2.5%) 580 7.1% 672 7.8% 1,039 11.1% 1,413 14.4% Amortization of cert

  86. Slide 86: Constant currencies

    Constant currencies Change % cc (non-IFRS Percentage point $ measure) currency impact 2017 compared to 2016 Net sales 3 3 - Net income/(loss) nm nm nm Core net income (2) 2 (4) 2018 compared to 2017 Net sales 5 5 - Net (loss)/income nm nm nm Core net income 7 8 (1) 2019 compared to 2018 Net sales 3

  87. Slide 87: Reconciliation of Free cash flow to Net cash flows from operating activities

    Reconciliation of Free cash flow to Net cash flows from operating activities ($ millions) 2019 2021 2022 2023 2024 Net cash flows from operating activities 920 1,345 1,217 1,388 2,077 Purchase of property, plant & equipment (553) (700) (636) (658) (473) Free cash flow 367 645 581 730 1,604

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Alcon — Investor Day (March 2025) on 6ix