Cibus, Inc. · NASDAQ:CBUS
Cibus — Calyxt — Merger or Acquisition (April 2023)
22 slides from Cibus's merger presentation, Apr 4, 2023
Slide 1: The Future of Breeding: Driving Sustainable Agriculture
Exhibit 99.1 The Future of Breeding™ D r i v i n g S u s t a i n a b l e A g r i c u l t u re™ A p r i l 2 0 2 3
Slide 2: Bill Gates quote on seed innovation
“Investing in seed innovation is one of the best ways to ensure food security.” - Bill Gates 2 2
Slide 3: The Past & the Present: Breeding is Lengthy and Random
The Past & the Present The Oldest Industry without a Technological Moment Breeding is Still a Lengthy and Random Process 3
Slide 4: Gene Editing Can be that Moment
Gene Editing Can be that Moment Regulation of Traits as Similar to Conventional Breeding is Enabling this Moment Scale is Making Gene Editing the “Analogue to Digital Moment” for Agriculture The EU is a Key Driver - The European Union has announced that in Q2 2023, they will release their proposals
Slide 5: Gene Editing Transforms Breeding Trait Development
Gene Editing Transforms Breeding Trait Development in a Scale Semi-Automated “End-to-End” Process Enables a “Timebound & Predictable” System to Develop Traits “Nature Identical” Traits Traits from Trait Machine that are conventional breeding like. Bio-Mfg. Standards Pharma Standard Quality Control &
Slide 6: Background: Plant Genetics Business
Background Plant Genetics Business FOUNDED EMPLOYEES - Cibus Develops Genetic Traits for Seed Companies 2001 ~200 HEADQUARTERS Products San Diego, CA 1) Productivity Traits for Major Crops Productivity traits that make crops more adaptable to the environment, have increased yields or require less ch
Slide 7: Merger Combines Key Technologies in Gene Editing
See: Cibus.com for Announcement & Details https://www.Cibus.com/press-release.php Merger Combines Key Technologies in Gene Editing Productivity Traits Sustainable Ingredients Gene Edited Plants Plants, Micro-Organisms Oil Seeds Cereals Yarrowia Plant Cell Matrix (Both) (Both) (Cibus) (Calyxt) 7
Slide 8: Technology & Business: RTDS/Trait Machine Breeding Platform
Technology & Business RTDS®/Trait Machine™ - Revolutionary Breeding Platform 1- Changes Scale, Speed & Accuracy 2- Changes Opportunity Set - Disease, Nitrogen Use, Climate Change 8
Slide 9: RTDS Non-GMO vs GMO Trait Technology
Foreign DNA / Gene Edit RTDS® Transgene Insertion Cibus RTDS Trait Technology Proprietary Non-GMO GMO Trait Technology Genetic Modification w/o Gene Editing Platform Genetic Modification integrating integrating Foreign DNA/Transgene Foreign DNA/Transgene Traits are Conventional Breeding-like” PROCES
Slide 10: RTDS Drives Step Changes in Breeding Two Ways
RTDS Drives Step Changes in Breeding Two Ways 1– Prototyping: Accelerates Development & Proof of Concept 2– Production: Accelerates Speed to Market. Trait Machine Trait Machine directly Once a trait is developed, Trait Machine accelerates accelerates prototyping or edits a customer’s time to commerc
Slide 11: Business Model: Traits Distributed in Seeds by Seed Companies
Business Model: Traits Distributed in Seeds by Seed Co’s Seed Companies In-License Traits for Specific Characteristics E.G.: In 2018, Corteva disclosed that they pay ~$750 million in Trait Royalties.(*) WHO TURN TO TURN TO Farmers Seed Companies Plant Trait Developers Challenged by the impacts of Se
Slide 12: Revenue Model: Royalties
Revenue Model: Royalties Long History of Trait Licensing & Royalty Payments Royalties (Trait Fees) based on “Value Per Acre” Trait Fees NA & SA Trait Market $2.1B Soybean ➢ Accessible Acres ~400 MM $1.0B ➢ Trait Fee Acres Cotton Major Crops 2020 Est. > 300 MM Trait Fees (NA & SA) $0.4B ➢ Avg. Trait
Slide 13: Product Review Pipeline
Product Review Pipeline 3- Developed Products 3- Advanced Products 13
Slide 14: Well Developed Broad Initial Pipeline
Well Developed Broad Initial Pipeline EST. CIBUS TRAIT ACRES 6 Traits Initially Targeting Canola, Rice & Soybean* Trait Machine Enables Serving Same Trait to Multiple Crops, Customers SPECIALTY TRAITS ~30 MM Four of the Six Traits have Applicability for Multiple Crops * Acres based on Canola, Rice,
Slide 15: Initial Commercial Model: Trait Machine Platforms for Crops
Initial Commercial Model: Trait Machine Platforms for 3 Crops (Canola, Rice, Soybean) Addressing >250 MM Acres 4 of 6 Trait Products Linked to Multiple Crops; 3 Traits Starting Commercialization Cibus’ Initial Trait Machine Platforms Service > 250 Million Acres Acres * Mkt. Note: See slide 24 for da
Slide 16: Lead Developed Trait: Pod Shatter Reduction
Lead Developed Trait: PSR: Pod Shatter Reduction - Canola/WOSR Quantifiable Savings & Pricing, Recently Issued Product Patent*, Initial Trait Acres ~15 MM Commercial Progress: POD Shatter Reduction Developed & Transferring Sheaths or pods shatter in rain/high winds, causing yield Collaborations. los
Slide 17: Lead Advanced Trait: Sclerotinia White Mold Resistance
Lead Advanced Trait Sclerotinia White Mold Resistance The First Disease Trait, Major Need in Canola & Soybean, Est. Trait Fees Acres ~80 MM Sclerotinia Resistance Major Crops Canola/ Soybean Sclerotinia WOSR Builds plant’s defense mechanisms Resistance to prevent Sclerotinia from infecting Est. Trai
Slide 18: Corn & Wheat Platforms Will Add to TAM
Corn & Wheat Platforms Will Add to TAM* Timeline: Corn and Wheat Trait Machine Platform Expected by 2025. Major collaborations are Expected in both Crops by 2024. Accessible Acreage for the 5 Major Crops is ~ 530 Million Acres Accessible TRAIT ACRES * Acres based on Corn and Wheat in N.A..,S.A., EU
Slide 19: Multi-Crop Strategies Drive Business
Multi-Crop Strategies Drive Business The Business is Focused on Developing “Blockbusters” - Multi-crop Traits with 100 Million Acre+ Market Need - Targeting Trait Fees Ranging from $5 to $30 per Acre Target Areas Sustainable Ingredients Resistance Traits Efficiency Traits PLANT OUTPUTS CLIMATE CHANG
Slide 20: Tech Strategy: Crop Specific Trait Machine Platforms
Tech Strategy: Crop Specific Trait Machine Platforms Build Crop Specific Platforms with a Pipeline of Stacked Traits Available to Each Customer. Trait Machine Enables Incorporating (or Stacking) Multiple Traits Directly in a Specific Crop. Example: Cibus has a Multi-Trait Pipeline for Canola Est. Ci
Slide 21: Business Strategy
Business Strategy: ➢ Build Trait Machine Crop Platforms as Breeding Extensions for all Major Crops ➢ Build Family of 100 Million Acre + Multi-Crop Traits Trait Fees $2.1B Soybean The Underlying Scale of Traits Major Crops $1.0B NA&SA ➢ Major Traits are Applicable Cotton ~400 MM Acres 2020 Est. to an
Slide 22: Disclaimer
Disclaimer Securities Law Matters Acreage Data This presentation has been prepared by Cibus Global, LLC (the Company ), and the Company This presentation has 2 available acreage calculations: TAM-Total Accessible Acres and Trait is responsible for its contents. It shall not constitute an offer, nor