Uniphar Plc · EURONEXT:UPR
Uniphar — Webinar 10 ProVen: Antibiotics (October 2017)
10 slides from Uniphar's conference presentation, October 2017
Slide 1: Webinar 10 ProVen: Antibiotics
Webinar 10 ProVen: Antibiotics
Slide 2: Antibiotics – The Most Prevalent and Potent Disruptors of the Microbiome
ProVen Antibiotics – The Most Prevalent and Potent Disruptors of the Microbiome
Slide 3: Antibiotics: The Greatest Medical Advance of the 20th Century
ProVen ANTIBIOTICS: THE GREATEST MEDICAL ADVANCE OF THE 20TH CENTURY 1928: Penicillin discovery (Sir Alexander Fleming, ‘Mould Juice’) 1942: Penicillin as a ‘Miracle Drug’ introduction 1940s-1960s: Golden Age - Discovery of a number of antibiotics • Pneumonia • Battlefield infections • Tuberculosis
Slide 4: Antibiotic Resistance: The Biggest Threat to Human Healthcare in the 21st Century
ProVen ANTIBIOTIC RESISTANCE : The Biggest Threat to Human Healthcare in the 21st Century • Over prescribed in humans • Livestock industry
Slide 5: Approximately 5.93 million day courses per year in Ireland
ProVen This is equivalent to approximately 5.93 million 7 day courses per year in Ireland
Slide 6: Ireland – Facts and Figures on Antibiotic Use
ProVen Ireland – Facts and Figures on Antibiotic Use • The population of Ireland in 2017 is 4.74 million. • Community antibiotic use is approximately 1.25 courses per person per year in Ireland • Hospital use is increasing from 2007 to 2012 from 77.2 to 86.0 DDD per 100 bed days – so virtually every
Slide 7: Antibiotic Use in Ireland is Amongst the Highest in Europe
ProVen Antibiotic Use in Ireland is Amongst the Highest in Europe, but Counties Vary Considerably in Prescription Level.
Slide 8: Differential Effects of Antibiotics on the Intestinal Microbiome
ProVen Differential Effects of Antibiotics on the Intestinal Microbiome
Slide 9: Differential Effects of Antibiotics on the Intestinal Microbiome
ProVen Differential Effects of Antibiotics on the Intestinal Microbiome Antibiotic Disruption of Microbiome Administration Small Intestine Large Intestine Oral Absorbed Antibiotics High Low Oral Non Absorbed Antibiotics High High Intravenous Antibiotics Moderate Low
Slide 10: Antibiotic Induced Dysbioses and Potential Disease
ProVen Antibiotic Induced Dysbioses and Potential Disease
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