Ginkgo Bioworks Holdings, Inc. · NYSE:DNA

Ginkgo Bioworks — Q3 2024 Earnings Presentation

40 slides from Ginkgo Bioworks's earnings presentation, Nov 12, 2024

  1. Slide 1: Q3 2024 Update & Business Review

    Property of Ginkgo Bioworks — 1 Grow with Ginkgo Q3 2024 Update & Business Review Q1 2024 UPDATE & BUSINESS REVIEW November 12, 2024

  2. Slide 2: Disclaimer: Forward-Looking Statements

    Disclaimer Property of Ginkgo Bioworks — 2 FORWARD-LOOKING STATEMENTS This presentation, the conference call and webcast contain contain certain forward-looking statements within the meaning of the federal securities laws, including statements regarding our plans, strategies, including with respect

  3. Slide 3: Agenda

    Property of Ginkgo Bioworks — 3 Introduction Jason Kelly, Co-Founder and CEO Q3 2024 Financial Update Mark Dmytruk, CFO Agenda Q3 2024 UPDATE & BUSINESS REVIEW Strategic Review Jason Kelly, Co-Founder and CEO Q&A Session Moderated by Megan LeDuc, Manager of Investor Relations

  4. Slide 4: Our Mission and Objectives

    Property of Ginkgo Bioworks — 4 OUR MISSION Make biology easier to engineer OBJECTIVES Reaching Adjusted EBITDA breakeven by the end of 2026 while maintaining a cash margin of Q3 2024 UPDATE & BUSINESS REVIEW safety Cutting costs while serving current customers Growing revenue in solutions and expan

  5. Slide 5: Annualized cost savings target of ~$200 million by mid-2025

    Reminder: Ginkgo targets annualized cost savings of ~$200 million Property of Ginkgo Bioworks — 5 by mid-2025 2024 2025 Total SPEND Annualized Savings Annualized Savings Annualized Savings Target by CATEGORY Original Target Original Target mid-2025 People OpEx (1) $75M $10M $85M Non-People OpEx $25M

  6. Slide 6: Agenda

    Property of Ginkgo Bioworks — 6 Introduction Jason Kelly, Co-Founder and CEO Q3 2024 Financial Update Mark Dmytruk, CFO Agenda Q3 2024 UPDATE & BUSINESS REVIEW Strategic Review Jason Kelly, Co-Founder and CEO Q&A Session Moderated by Megan LeDuc, Manager of Investor Relations

  7. Slide 7: Cell Engineering Highlights

    Cell Engineering Highlights (Unaudited) Property of Ginkgo Bioworks — 7 CELL ENGINEERING REVENUE ($M) CURRENT ACTIVE PROGRAMS TOTAL ACTIVE CUSTOMERS BY TYPE 17% 7% 102% Government Pharma & Q3 2024 UPDATE & BUSINESS REVIEW Biotech Includes recognition of $45M non-cash deferred revenue from Motif. Foo

  8. Slide 8: New programs in the quarter showed strong execution in biopharma

    New programs in the quarter showed strong execution in the Property of Ginkgo Bioworks — 8 biopharma industry NEW PROGRAMS YEAR TO DATE Other Customer Contracts ● 2 out of the 14 contracts are Datapoints deals Q3 2024 UPDATE & BUSINESS REVIEW ● 7 out of the 14 contracts are biopharma deals New Progr

  9. Slide 9: Biosecurity Highlights

    Biosecurity Highlights Property of Ginkgo Bioworks — 9 (Unaudited) BIOSECURITY REVENUE ($M) Ginkgo HQ CUBE-D 20 North America 24 Europe 34 Asia Q3 2024 UPDATE & BUSINESS REVIEW 30 8 Africa South BIOSECURITY GROSS PROFIT MARGIN America 3 Oceania Countries in which Ginkgo has programs, pilots, or sign

  10. Slide 10: Q3 2024 Financial Summary

    Q3 2024 Financial Summary (Unaudited) Property of Ginkgo Bioworks — 10 Three Months Ended September 30, Nine Months Ended September 30, In millions of USD except % YoY 2024 2023 % YoY 2024 2023* % YoY Revenue: Cell Engineering ⁽¹⁾ $ 75 $ 37 102% $ 139 $ 117 19% Biosecurity 14 18 (24%) 44 100 (56%) T

  11. Slide 11: Ginkgo updates guidance to reflect $45 million non-cash deferred revenue release

    Ginkgo updates guidance solely to reflect the $45 million non-cash Property of Ginkgo Bioworks — 11 deferred revenue release HISTORICAL OUTLOOK In millions of USD FY2021 FY2022 FY2023 FY2024 Revenue Cell Engineering $113 $144 $144 $165-185 Services $86 $106 $139 $120-140 Downstream Value $27 $38 $4 -

  12. Slide 12: Agenda

    Property of Ginkgo Bioworks — 12 Introduction Jason Kelly, Co-Founder and CEO Q3 2024 Financial Update Mark Dmytruk, CFO Agenda Q3 2024 UPDATE & BUSINESS REVIEW Strategic Review Jason Kelly, Co-Founder and CEO Q&A Session Moderated by Megan LeDuc, Manager of Investor Relations

  13. Slide 13: We believe…

    Property of Ginkgo Bioworks — 13 We believe… 1 2 3 Ginkgo has the potential Ginkgo continues to build The H5N1 threat has to exceed cost cutting its customer relationships progressed in recent goals in 2024 while as it delivers technical weeks and Ginkgo stands maintaining revenue milestones and sig

  14. Slide 14: We believe…

    Property of Ginkgo Bioworks — 14 We believe… 1 2 3 Ginkgo has the potential Ginkgo continues to build The H5N1 threat has to exceed cost cutting its customer relationships progressed in recent goals in 2024 while as it delivers technical weeks and Ginkgo stands maintaining revenue milestones and sig

  15. Slide 15: Restructuring accomplishments to date

    Restructuring accomplishments to Property of Ginkgo Bioworks — 15 Annualized, Run-Rate Cash Opex (1) ~$515M (1) date ~$500M Space ● Transitioning out of several offices to reduce overall Space footprint ~$375M (1) ● Boston area site consolidation complete by end of year, approximately 6 months ahead o

  16. Slide 16: Six months ahead of schedule in site consolidation

    Property of Ginkgo Bioworks — 16 Ginkgo is six months ahead of schedule in Site Consolidation Boston / Cambridge Evry ✘1 ABP (Parcel O/P) 21-25 Drydock ✘ Sold Altar SAS to Lesaffre including 23 Drydock Zeist, NDL ALE entity in France. Transaction 27 Drydock 451D Ultrechtseweg 48 closed 9/30/2024. ✘10

  17. Slide 17: Restructuring focus areas moving forward

    Property of Ginkgo Bioworks — 17 Restructuring focus areas moving forward Subleasing Non-Productive Space & Additional Space Consolidation 1 Find tenants to maximize the use of excess real estate resources & continued optimization of operational footprint required to deliver programs. Strict Focus o

  18. Slide 18: We believe…

    Property of Ginkgo Bioworks — 18 We believe… 1 2 3 Ginkgo has the potential Ginkgo continues to build The H5N1 threat has to exceed cost cutting its customer relationships progressed in recent goals in 2024 while as it delivers technical weeks and Ginkgo stands maintaining revenue milestones and sig

  19. Slide 19: Expanding into tools opens new revenue from existing assets

    Property of Ginkgo Bioworks — 19 Expanding into tools opens new revenue from existing assets CUSTOMIZATION FOR CUSTOMER & TECHNICAL RISK BORNE BY GINKGO CELL ENGINEERING SOLUTIONS CELL ENGINEERING TOOLS HIGHER Asset Licensing Deal (i.e. selling a drug candidate to a large biopharma) GINKGO CUSTOMIZA

  20. Slide 20: Ginkgo remains focused on delivering for customers

    Property of Ginkgo Bioworks — 20 Ginkgo remains focused on delivering for customers, while Q3 2024 UPDATE & BUSINESS REVIEW remaining disciplined in cutting costs

  21. Slide 21: Ginkgo advances collaboration with Merck to improve biologics manufacturing

    Property of Ginkgo Bioworks — 21 Ginkgo Bioworks Advances Ginkgo continues to deliver for its Collaboration with Merck to customers as it reaches a major Improve Biologics Manufacturing research milestone with Merck “We're excited to achieve the first milestone of our collaboration with Merck and con

  22. Slide 22: Novo Nordisk represents a model for key customers

    Novo Nordisk represents a model for what we can Property of Ginkgo Bioworks — 22 accomplish with key customers as we demonstrate our capabilities Ginkgo Bioworks and Novo Ginkgo Bioworks and Novo Expansion of the Nordisk to Collaborate on Nordisk Expand Alliance to collaboration on expression Expres

  23. Slide 23: Datapoints products: cell-based data

    Beyond our traditional Solutions Property of Ginkgo Bioworks — 23 offerings, we’ve also launched two Datapoints products Flexibility & Choose from cell types, compound Customization library, data readouts. We handle both perturbation and End-to-End readouts. Tell us what you need, and we will deliver

  24. Slide 24: Datapoints products: antibody developability

    Beyond our traditional Solutions Property of Ginkgo Bioworks — 24 offerings, we’ve also launched two Datapoints products ● Screen over 2,400 antibody sequences in parallel Scale ● Enabled by our highly automated lab and over $1 billion of invested wet lab infrastructure 1. We take your antibody seque

  25. Slide 25: We believe…

    Property of Ginkgo Bioworks — 25 We believe… 1 2 3 Ginkgo has the potential Ginkgo continues to build The H5N1 threat has to exceed cost cutting its customer relationships progressed in recent goals in 2024 while as it delivers technical weeks and Ginkgo stands maintaining revenue milestones and sig

  26. Slide 26: H5N1 outbreak shifted from livestock threat to human transmission

    Property of Ginkgo Bioworks — 26 The H5N1 outbreak has shifted from a threat to livestock to human transmission in a matter of months NEWS AS OF AUG 8, 2024 NEWS AS OF NOV 12, 2024 How Countries Are Feds to spend CDC calls for US detects H5N1 Preparing for a millions to contain expanded testing for

  27. Slide 27: Ginkgo's current H5N1 offerings

    Ginkgo’s current H5N1 offerings work Property of Ginkgo Bioworks — 27 GINKGO’S CROSS-SPECIES H5N1 US TRACKER to detect and prevent the spread ● Detects and provides genomic information for Flu A in raw milk Testing & ● Delivers necessary information to accelerate the Sequencing development of diagnos

  28. Slide 28: Ginkgo's next steps on H5N1

    Property of Ginkgo Bioworks — 28 Serologic Evidence of Recent Recent CDC announcements indicate Infection with Highly the need for strategies to detect and Pathogenic Avian Influenza A(H5) Virus Among Dairy prevent the spread of H5N1 Workers — Michigan and Colorado, June–August 2024 GINKGO’S NEXT STE

  29. Slide 29: Let's grow the world we want to see

    world Let’s grow the we want to see Q1 2024 UPDATE & BUSINESS REVIEW Property of Ginkgo Bioworks — 29

  30. Slide 30: Agenda

    Property of Ginkgo Bioworks — 30 Introduction Jason Kelly, Co-Founder and CEO Q3 2024 Financial Update Mark Dmytruk, CFO Agenda Q3 2024 UPDATE & BUSINESS REVIEW Strategic Review Jason Kelly, Co-Founder and CEO Q&A Session Moderated by Megan LeDuc, Manager of Investor Relations

  31. Slide 31: Appendix

    APPENDIX Q1 2024 UPDATE & BUSINESS REVIEW Property of Ginkgo Bioworks — 31

  32. Slide 32: Cell Program Counts

    Cell Program Counts Property of Ginkgo Bioworks — 32 Three Months Ended September 30, Nine Months Ended September 30, LTM (1) 2024 2023 2024 2023 2024 New Programs 11 21 38 55 61 Current Active Programs 136 116 162 139 169 Cumulative Programs 280 219 280 219 280 New Programs: New Programs represent

  33. Slide 33: Cell Engineering Revenue

    Cell Engineering Revenue (Unaudited) Property of Ginkgo Bioworks — 33 In millions of USD, except % of total Three Months Ended September 30, Nine Months Ended September 30, 2024 % of Total 2023 % of Total 2024 % of Total 2023 % of Total Related Parties $ 47 62% $9 23% $ 52 37% $ 20 17% Third Parties

  34. Slide 34: Adjusted EBITDA Reconciliation

    Adjusted EBITDA Reconciliation (Unaudited) Property of Ginkgo Bioworks — 34 In millions of USD Three Months Ended September 30, Nine Months Ended September 30, 2024 2023 2024 2023* Net loss ⁽¹⁾ $ (56.4) $ (302.9) $ (439.5) $ (681.2) Interest income, net (9.3) (15.0) (31.3) (43.9) Income tax expense

  35. Slide 35: M&A and Restructuring Related Costs

    M&A and Restructuring Related Costs (Unaudited) Property of Ginkgo Bioworks — 35 In millions of USD Three Months Ended September 30, Nine Months Ended September 30, 2024 2023 2024 2023 M&A and Restructuring Related Costs (excl. SBC) Amount included in Research and Development expenses (excl. SBC): 0

  36. Slide 36: Segment Information

    Segment Information (Unaudited) Property of Ginkgo Bioworks — 36 In millions of USD, except % YoY Three Months Ended September 30, Nine Months Ended September 30, 2024 2023 % YoY 2024 2023 % YoY Revenue: Cell Engineering $ 75 $ 37 102% $ 139 $ 117 19% Biosecurity 14 18 (24%) 44 100 (56%) Total Reven

  37. Slide 37: Stock-Based Compensation

    Stock-Based Compensation (Unaudited) Property of Ginkgo Bioworks — 37 In millions of USD, except % YoY Three Months Ended September 30, Nine Months Ended September 30, 2024 2023 % YoY 2024 2023 % YoY Total Stock-Based Compensation $ 14.0 $ 53.7 (74%) $ 94.6 $ 191.3 (51%) Amount included in Research

  38. Slide 38: Stock Based Compensation Expense Supplement

    Stock Based Compensation Expense Supplement (Unaudited) Property of Ginkgo Bioworks — 38 As disclosed in our SEC filings, the vast majority of Ginkgo’s stock-based compensation expense since going public relates to the accounting treatment of RSUs granted prior to Ginkgo becoming a publicly traded co

  39. Slide 39: Founder Selling Supplement

    Founder Selling Supplement Property of Ginkgo Bioworks — 39 Ginkgo’s Founders currently own nearly 20% of the outstanding shares of Ginkgo, the vast majority of which are in Class B shares ● Class B shares are not freely tradable (must be converted to Class A) and are often not shown on automated da

  40. Slide 40: Share Supplement

    Share Supplement Property of Ginkgo Bioworks — 40 Illustrative Fully-Diluted Share Count Shares in thousands Basic Shares (1) 53,683 RSUs (2) 4,078 Fully-Diluted Shares 57,761 Memo: Remaining Earnout Shares Outstanding (3) 3,796 Q3 2024 UPDATE & BUSINESS REVIEW Memo: Shares Underlying Warrants (4) 5

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