Nykode Therapeutics Asa · OSL:NYKD

Nykode Therapeutics Asa — Corporate Update (November 2021)

20 slides from Nykode Therapeutics Asa's corporate update, Nov 23, 2021

  1. Slide 1: License and collaboration agreement with Regeneron

    License and collaboration agreement with Regeneron Vaccibody becomes Nykode Therapeutics November 23, 2021

  2. Slide 2: Forward-looking statement

    Forward-looking statement This announcement and any materials distributed in connection with this presentation may contain certain forward- looking statements. By their nature, forward-looking statements involve risk and uncertainty because they reflect the company’s current expectations and assumpt

  3. Slide 3: Agenda

    Agenda License and collaboration agreement with Regeneron Vaccibody becomes Nykode Therapeutics Nykode Therapeutics | Webcast | Non-confidential 3

  4. Slide 4: Nykode enters into multi-target license and collaboration agreement with Regeneron

    Nykode Therapeutics enters into multi- target license and collaboration agreement with Regeneron to develop innovative vaccines against cancer and infectious diseases Nykode Therapeutics | Webcast | Non-confidential 4

  5. Slide 5: Vaccibody becomes Nykode Therapeutics

    Vaccibody becomes Nykode Therapeutics Nykode Therapeutics | Webcast | Non-confidential 5

  6. Slide 6: Nykode Therapeutics – Unique vaccine and novel therapeutic platform

    Nykode Therapeutics – Unique vaccine and novel therapeutic platform  Clinical stage immunotherapy company  Leading vaccine technology platform targeting antigens to antigen presenting cells  Well tolerated, easily manufactured and induce robust CD8 and CD4 T cell responses  Platform can fuel mul

  7. Slide 7: 01 Regeneron collaboration

    01 Regeneron collaboration Multitarget, exclusive license and collaboration agreement 7

  8. Slide 8: Regeneron – Nykode Therapeutics collaboration overview

    Regeneron – Nykode Therapeutics collaboration overview DISCOVERY, DEVELOPMENT AND COMMERCIALIZATION OF 5 NOVEL VACCINE PROGRAMS AGAINST CANCER AND INFECTIOUS DISEASES  Vaccine generation  Antigen identification  Vaccine characterization  Preclinical development  Product supply through phase 1 

  9. Slide 9: Regeneron – Nykode Therapeutics deal terms overview

    Regeneron – Nykode Therapeutics deal terms overview  3 oncology and 2 novel infectious disease programs, each may include several vaccine candidates  Regeneron to cover all research, development and commercialization costs  Upfront of USD 30 million and USD 20 million equity investment at 20% pre

  10. Slide 10: Pipeline

    Pipeline Broad oncology coverage and strong partnerships. Leveraging platform within infectious diseases Upcoming Program Indication Discovery/Preclinical Phase 1 Phase 2 Phase 3 Partnerships Milestones Oncology Off the shelf 2H21: Trial Fully VB10.16 HPV16+ cervical cancer3 Enrolled 1H22: Interim D

  11. Slide 11: Regeneron is a partner of choice for Nykode Therapeutics

    Regeneron is a partner of choice for Nykode Therapeutics REGENERON OVERVIEW  10,000+ employees  Scientifically led and focused on innovative Deep scientific expertise and drug development successful track record  Brings unique insights on antigen selection for the collaboration programs  Proven

  12. Slide 12: Perfect fit with Nykode Therapeutics growth strategy

    Perfect fit with Nykode Therapeutics growth strategy  Validates our unique therapeutic vaccine platform  Expands and fast tracks our pipeline into novel and innovative areas across oncology and infectious diseases  Fully complementary to current and future pipeline  Cash flow allows us to accele

  13. Slide 13: 02 Vaccibody becomes Nykode Therapeutics

    02 Vaccibody becomes Nykode Therapeutics 13

  14. Slide 14: Transforming the Company from vaccines to a broader platform

    Transforming the Company from vaccines to a broader platform  Three major deals proving our leading vaccine platform  Generated several hundred novel constructs and built know-how in coding new medicines with unique properties  Continued focus on innovation - improve and expand our modular elemen

  15. Slide 15: Building further on our core strength

    Building further on our core strength COMBINING MODULAR ELEMENTS TO GENERATE SUPERIOR MEDICINES  Breaking down the boundaries of conventional drug design  Combining genes to generate novel drugs with unique properties Nykode Therapeutics | Webcast | Non-confidential 15

  16. Slide 16: New name captures ambition of platform and Norwegian heritage

    New name captures ambition of platform and Norwegian heritage  Encapsulates vision of finding new ways of coding Coding novel medicine medicines  Draws on our heritage by using the Norwegian words for the words new “ny” and code “kode” Nykode Therapeutics | Webcast | Non-confidential 16

  17. Slide 17: Nykode's modular platform enables generation of multiple specific and innovative products

    Nykode’s modular platform enables generation of multiple specific and innovative products APC-specific Ag delivery and Expanded use of modularity stimulation Building additional Novel Infectious disease Cancer vaccines combinations and vaccines modules structures Vaccines against Novel therapeutics

  18. Slide 18: Signifying a new phase of growth and development

    Signifying a new phase of growth and development  Exploiting future potential building on our core competences  Significantly expanding our pipeline through internal and selected partnered programs With a common basis of generating novel  Building the organization with strong focus on continuous

  19. Slide 19: Strong financial foundation for achieving our vision

    Strong financial foundation for achieving our vision  Financially well positioned to grow and execute the Company’s strategy over the next years  Total available liquidity of USD 189 million on September 30, 2021 − Cash and cash equivalents of USD 172.6 million − Liquid money market funds of USD 1

  20. Slide 20: Thank you

    Contact Michael Engsig CEO IR@vaccibody.com THANK YOU Nykode Therapeutics | Webcast | Non-confidential

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