Charles River Laboratories International, Inc. · NYSE:CRL

Charles River Laboratories International — Merger or Acquisition (June 2010)

31 slides from Charles River Laboratories International's merger presentation, Jun 1, 2010

  1. Slide 1: Safe Harbor Statement

    Safe Harbor Statement This document includes "forward -looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Forward -looking statements may be identified by the use of words such as "anticipate," "believe," "expect," "estimate," "plan," "outlook," and "proj

  2. Slide 2: Non-GAAP Financial Measures and Additional Information

    Non-GAAP Financial Measures This presentation includes discussion of non-GAAP financial measures. We believe that the inclusion of these non-GAAP financial measures provides useful information to allow investors to gain a meaningful understanding of our core operating results and future prospects, w

  3. Slide 3: Charles River and WuXi: A Transformational Combination

    Charles River and WuXi: A Transformational Combination [] The combination creates the first fully integrated global early-stage contract research organization (CRO) * Offers a full range of products and services from molecule creation to first-in-human testing * Leverages increasing strategic import

  4. Slide 4: Timing of the Acquisition is Key

    Timing of the Acquisition is Key [] Critical inflection point in terms of rapid client consolidation and infrastructure reductions * Accelerating need for strategic outsourcing [] Clients are reducing the number of strategic partners to those with financial strength, scientific depth, global footpri

  5. Slide 5: Drives Profitable Revenue Growth

    Drives Profitable Revenue Growth [] Global outsourced discovery chemistry segment is estimated to be at least $2B in 2010, with a mid-teens CAGR over the next 3-5 years* * Currently ~20-30% outsourced [] Growth in Discovery Chemistry and other downstream services accelerated by pharma outsourcing *

  6. Slide 6: Enhances Top-Line Growth Potential by BPS

    Enhances Top-Line Growth Potential by 200 BPS '11-'13E Growth Potential Growth Drivers - -------------------------------------------------------------------------------- [] Improved demand for models used in toxicology [] Standard ~2% average annual price increase [] Continued double-digit growth of

  7. Slide 7: Revenue Synergies

    Revenue Synergies [] Cross-selling and combined sales force create incremental opportunity to drive more business upstream and downstream with existing and prospective clients based on unprecedented scope of early-stage portfolio [] Increased presence and scale in the emerging China market [] Mid-ti

  8. Slide 8: Significant Cross-Selling Opportunities

    Significant Cross-Selling Opportunities CRL WX Combined Top 20 Clients ('09) Rank Rank - -------------------------------------------------------------------------------- 1 Large Pharma Top 10 Top 5 Each Top 3 client 2 Large Pharma Top 5 Top 10 ----------------- 3 Large Pharma Top 5 Top 5 5%-6% of co

  9. Slide 9: 2011 Combined Financial Outlook

    2011 Combined Financial Outlook(1) - -------------------------------------------------------------------------------- Revenue(2) At least $1,675M - -------------------------------------------------------------------------------- Non-GAAP Operating Margin % Approx. 22% - -----------------------------

  10. Slide 10: 2011 General Assumptions

    2011 General Assumptions(1) [] Expect to recognize ~$20M of cost synergies * Public company costs, SG-and-A, and refinement of operating structure [] ~4.5% average interest rate on new debt * Term A rate expected to be LIBOR plus 275bps [] New debt of less than $950M [] Existing term loan is repaid

  11. Slide 11: Enthusiastic Client Response

    Enthusiastic Client Response [] Senior management of CRL and WX each have reviewed the transaction with their respective top 20 pharmaceutical and biotechnology clients * Response has been overwhelmingly positive * Follow-up meetings have been scheduled/initiated [] Clients are viewing this transfor

  12. Slide 12: Cultural Fit

    Cultural Fit [] WuXi is a client-focused service organization* Excellent client retention [] 100% retention of top 10 clients ('07-'09) * ~90% of WuXi's sales generated from US and European clients [] WuXi shares CRL's employee-centric culture [] Scientific depth and expertise differentiates CRL and

  13. Slide 13: Management Continuity

    Management Continuity [] Top WuXi executives to join CRL management team (3-year employment agreements) * Ge Li, PhD: Corporate EVP and President, Global Discovery and China Services o Joins CRL Board, along with two additional directors chosen by WuXi o Founded WuXi in 2000; previously helped found

  14. Slide 14: Integration Planning Well Underway

    Integration Planning Well Underway [] Minimal business overlap simplifies integration process [] Corporate integration team jointly headed by: * CRL: David P. Johst, EVP, Human Resources, General Counsel and CAO * WX: Edward Hu, COO [] Nine operational sub-teams already established and meeting to de

  15. Slide 15: Transaction Timeline

    Transaction Timeline [] HSR filed May 11, 2010 [] Preliminary proxy statement filed June 1, 2010 [] Still on track to close by 4Q10, subject to approval by each company's shareholders and the satisfaction of customary closing conditions and regulatory approvals * Shareholder approval process: o SEC

  16. Slide 16: A Transformational Combination

    A Transformational Combination [] First fully integrated global early-stage CRO [] Overwhelmingly positive response from top 20 clients [] Creates opportunities for substantial revenue synergies due to unique portfolio and global footprint [] Generates profitable revenue growth, driving long-term re

  17. Slide 17: A Transformational Combination

    A Transformational Combination Vv First fully integrated global early-stage CRO Overwhelmingly positive response from top 20 clients Creates opportunities for substantial revenue synergies due to unique portfolio and global footprint Generates profitable revenue growth, driving long-term return on i

  18. Slide 18: Transaction Summary

    Transaction Summary Purchase price [] ~$1.6B(1), including the assumption of WuXi's debt and cash Consideration [] $21.25(1) total per ADS subject to collar (below) per share [] $11.25 in cash plus [] $10.00 of CRL common stock determined by exchange ratio Exchange Ratio [] $10.00 divided by 20-day

  19. Slide 19: Charles River Today

    Charles River Today [] A leading in vivo biology company * $1.20B in net sales (FY '09) [] Unique portfolio of products and services focused on the research and development continuum for new drugs [] A multinational company with ~8,000 employees worldwide * ~70 facilities in 16 countries o Continuou

  20. Slide 20: WuXi Today

    WuXi Today [] A leading chemistry company * $270M in net sales (FY09) [] Service portfolio supports clients early with molecule creation, extending downstream through laboratory and manufacturing services [] Largest China-based CRO with ~4,200 employees worldwide * One of the largest employers of ch

  21. Slide 21: WuXi Overview

    WuXi Overview Headquarters [] Shanghai, China - -------------------------------------------------------------------------------- [] Laboratory services, consisting of synthetic and medicinal chemistry, DMPK/ADME, biology, microbiology, in vivo pharmacology, toxicology, pharmaceutical development, an

  22. Slide 22: WuXi Overview - History

    WuXi Overview - History [GRAPHIC OMITTED] Source: Based on WuXi's information as disclosed in its Form 20-F filed with the SEC on 04/23/2010 and other public documents. 23

  23. Slide 23: WuXi's Current Discovery Services

    WuXi's Current Discovery Services [GRAPHIC OMITTED] 24

  24. Slide 24: CRL's Current Preclinical Services

    CRL's Current Preclinical Services [GRAPHIC OMITTED] 25

  25. Slide 25: The New CRL: Global Integrated Services

    The New CRL: Global Integrated Services [GRAPHIC OMITTED] 26

  26. Slide 26: Leverages Increasing Strategic Importance of China

    Leverages Increasing Strategic Importance of China [] Supportive of global pharmas who view China as the new frontier for drug development [] Pharmas are taking advantage of cost leverage by placing chemistry in China * Lower cost, highly skilled scientists with advanced degrees [] Emerging opportun

  27. Slide 27: The New CRL Revenue Base

    The New CRL Revenue Base* [GRAPHIC OMITTED] - -------------------------------------------------------------------------------- Leveraging the increasing strategic importance of China - -------------------------------------------------------------------------------- * Based on FY 2009 combined sales.

  28. Slide 28: The New CRL Business Segments

    The New CRL Business Segments - -------------------------------------------------------------------------------- 2009 Combined Sales*: $1.5B - -------------------------------------------------------------------------------- [GRAPHIC OMITTED] DS: Discovery Services RMS: Research Models and Services P

  29. Slide 29: Synergies

    Synergies - -------------------------------------------------------------------------------- Public company [] Reduction of Board, SOX, audit, legal, stock and corporate exchange, insurance and related expenses [] Elimination of duplicative corporate overhead ~1/4 of cost synergies expenses and supp

  30. Slide 30: Accelerating Drug Development. Exactly.

    - -------------------------------------------------------------------------------- Accelerating Drug Development. Exactly. - -------------------------------------------------------------------------------- CRL ------ LISTED ------ NYSE [C] 2010 Charles River Laboratories International, Inc. 31

  31. Slide 31: Accelerating Drug Development. Exactly.

    Accelerating Drug Development. Exactly. CRL NYSE. — © 2010 Chares River Laboratories Iternatona, nc charles river

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