Bristol-myers Squibb Company · NYSE:BMY

Bristol-myers Squibb — Q1 2023 Earnings Presentation

17 slides from Bristol-myers Squibb's earnings presentation, Apr 27, 2023

  1. Slide 1: Q1 2023 Results

    Q1 2023 Results April 27, 2023

  2. Slide 2: Forward Looking Statements and Non-GAAP Financial Information

    Forward Looking Statements and Non-GAAP Financial Information This presentation contains statements about Bristol-Myers Squibb Company’s (the “Company”) future financial results, plans, business development strategy, anticipated clinical trials, results and regulatory approvals that constitute forwa

  3. Slide 3: Giovanni Caforio, MD

    Q1 2023 Results Giovanni Caforio, MD Chairman of the Board and Chief Executive Officer 3

  4. Slide 4: Q1 2023 Performance

    Q1 2023 Performance Strong Commercial Execution New Product Performance Global Net Sales $ in millions Q1:~$11.3B (3%) YoY; (1%) Ex-FX * $723 In-Line Brands & New Product $350 Portfolio: Q1 2022 Q1 2023 Q1:~$9.3B +8% YoY; +10% Ex-FX * Revenues more than doubled vs prior year Strong Financial Executi

  5. Slide 5: Near-term Catalysts Across Diversified Portfolio

    Near-term Catalysts Across Diversified Portfolio 2023 Key Milestones 2024/2025 Key Milestones  Initiation of pivotal Metastatic:  1L MF Ph3 Early Stage: Reblozyl post-transplant  1L HCC Ph3 (CM-9DW) (INDEPENDENCE)  Neo-adjuvant NSCLC Ph3 iberdomide Opdivo maintenance H2H vs  1L+ MSI High CRC Ph

  6. Slide 6: New Product Portfolio Significantly De-Risked with Important Catalysts Ahead

    New Product Portfolio Significantly De-Risked with Important Catalysts Ahead Key Milestones $25B+ Beyond Non-Risk Adjusted* • Camzyos nHCM • Opdualag Adj. Mel $4B+ • Sotyktu SLE • Opdualag 2L+ MSS CRC • Opdualag 1L NSCLC $4B+ $10B - $13B Risk-Adjusted Sales Planned Next 1-2 Years  Breyanzi 3L+ CLL

  7. Slide 7: David Elkins

    Q1 2023 Results David Elkins Executive Vice President and Chief Financial Officer 7

  8. Slide 8: Strong Total Company Performance

    Strong Total Company Performance Total Company Sales ~$11.3B (3%) YoY, (1%) Ex-FX* $B Q1 Net Sales1 YoY % Ex-FX* % $2.0 Total Company $11.3 (3%) (1%) $3.0 In-Line Products $8.6 +4% +6% New Product $0.7 ** ** $9.3 Portfolio $8.6 In-Line Products & $9.3 +8% +10% New Product Portfolio Recent LOEs2 $2.0

  9. Slide 9: New Product Portfolio Sales Performance

    New Product Portfolio Sales Performance Revenues more than doubled vs prior year +12% or +11% Ex-FX* growth vs prior quarter $ in millions $ in millions $723 $723 $16 $16 $25 $645 $25 $29 $7 $29 $34 $23 $34 $16 $71 $37 $71 $55 $78 $78 $79 $350 $117 $117 $104 $18 $23 $44 $147 $147 $125 $36 $6 $67 $20

  10. Slide 10: Q1 2023 Solid Tumor Product Summary

    Q1 2023 Solid Tumor Product Summary Q1 Global Net Sales Opdivo • U.S. growth driven by demand in 1L lung, upper GI $M YoY % Ex-FX* % indications & adj. bladder cancer • Ex-U.S. growth from 1L lung & upper GI indications $2,202 +15% +17% Opdualag $508 (1%) +2% • 3rd approved I-O agent; potential to b

  11. Slide 11: Q1 2023 Cardiovascular Product Summary

    Q1 2023 Cardiovascular Product Summary Q1 Global Net Sales $M YoY % Ex-FX* % $M YoY % Ex-FX* % $3,423 +7% +8% $29 --- --- Best-in-class & leading OAC within category First-in-class myosin inhibitor • U.S. robust underlying demand strength • U.S. increase in total treated & commercial dispensed patie

  12. Slide 12: Q1 2023 Hematology Product Summary

    Q1 2023 Hematology Product Summary Q1 Global Net Sales1 Revlimid – Impact from Gx entry; FY 2023 revenue projection of ~$6.5B 1 $M YoY % Ex-FX* % Pomalyst – Growth driven by demand for triplet-based regimens $1,750 (37%) (37%) in earlier lines & favorable buying patterns ex-U.S. Reblozyl $832 +1% +2

  13. Slide 13: Q1 2023 Immunology Product Summary

    Q1 2023 Immunology Product Summary Q1 Global Net Sales % $M YoY % Ex-FX* % % $M YoY % Ex-FX* % $764 (4%) (1%) $16 --- --- $78 ** ** First-in-class selective allosteric TYK2 inhibitor **In excess of +100% • U.S. continued strong early adoption; significant demand growth in Q1 Zeposia • Focused on dri

  14. Slide 14: Q1 2023 Financial Performance

    Q1 2023 Financial Performance US US GAAP GAAP Non-GAAP Non-GAAP * $ in billions, except EPS Q1 2023 Q1 2022 Q1 2023 Q1 2022 Total Revenues, net 11.3 11.6 11.3 11.6 Gross Margin % 77.4% 78.8% 77.8% 79.2% Operating Expenses1 4.1 4.1 4.0 4.0 Acquired IPR&D 0.1 0.3 0.1 0.3 Amortization of Acquired Intan

  15. Slide 15: Balanced Approach to Capital Allocation

    Balanced Approach to Capital Allocation Cash flow from Operations $B Business • Prioritize opportunities to further diversify Development portfolio & strengthen long-term outlook $3.8 $3.3 $3.7 $3.0 • Continued debt reduction $2.3 Balance Sheet ‒ ~$1.6B in debt repayments in Q1 Strength • Maintain s

  16. Slide 16: 2023 Guidance

    2023 Guidance US GAAP* Non-GAAP* February (Prior) April (Revised) April (Affirm) Total Revenues ~2% increase No Change ~2% increase Reported Rates Total Revenues ~2% increase No Change ~2% increase Ex-FX Revlimid ~$6.5 billion No Change ~$6.5 billion Gross Margin % ~77% No Change ~77% Operating Expe

  17. Slide 17: Q1 2023 Results Q&A

    Q1 2023 Results Q&A Giovanni Caforio, MD Chris Boerner, PhD Chairman of the Board, Executive VP, Chief Executive Officer Chief Operating Officer Samit Hirawat, MD David Elkins Executive VP, Executive VP, Chief Medical Officer, Chief Financial Officer Global Drug Development 17

Bristol-Myers Squibb Company — Q1 2023 Earnings Presentation on 6ix