Pathkey.ai Limited · ASX:PKY
Pathkey.ai — Shareholder Meeting (November 2020)
20 slides from Pathkey.ai's shareholder meeting presentation, Nov 30, 2020
Slide 1: Investor Update
Annual General Meeting info@opyl.ai www.opyl.ai Investor Update 30 November 2020 Artificial intelligence | Clinical trial design and recruitment | Social media
Slide 2: Disclaimer
Disclaimer This presentation has been prepared by Opyl Limited (“Opyl”). Each recipient of this presentation is deemed to have agreed to accept the qualifications, limitations and disclaimers set out below. None of Opyl, its subsidiaries or respective directors, officers, employees, advisers or repr
Slide 3: Overview
Overview Opyl is a digital health informatics company operating the in the global healthcare sector We applying artificial intelligence and predictive analytics to: - Improve clinical trial design and reduce risk - Accelerate patient recruitment to clinical trials - Deliver deep real world insights
Slide 4: Overview: three major points of failure in clinical trials
"Digital transformation of clinical trials is critical to improving productivity - artificial intelligence will be the key driver" Overview Deloitte - Intelligent Clinical Trials 2019 Opyl is aiming to solve three major points of failure in the USD$19.2Bn global clinical trials market: 1. Poor recru
Slide 5: Opyl solutions
Overview A scalable business model with three novel digital platforms and market intelligence capabilities addressing a large global Opyl solutions clinical trials market expected to reach USD$28.7Bn by 2025 growing at CAGR of 8.3% Clinical trial Clinical trial protocol design Social media recruitme
Slide 6: Market opportunity
Overview 33,198 clinical trials registered in 2020 (up by 38% since 2015) Market opportunity USD$19m Median cost of a clinical trial (2018) 11-40% Average cost per patient to enroll by trial type**: Of the clinical trial budget Phase I USD$15,700 per patient is spent on recruitment and Phase II USD
Slide 7: A year in Review: FY20
Overview A year in Review: FY20 Major Milestones Rebrand from ShareRoot to Opyl - digital health informatics focus Advanced clinical trial prediction/protocol design platform to proof of concept (Feb) Successfully delivered COVID19 clinical trial prediction data test (Aug) Advanced development of cl
Slide 8: Looking forward: FY21
Overview Looking forward: FY21 Launch clinical trial recruitment/retention platform - April 2021 Launch clinical trial protocol design/prediction platform - June 2021 Build global sales and marketing plan for both platforms - December 2020 to March 2021 Secure scale alliances to accelerate clinical
Slide 9: Opyl Platforms
Research & Development Opyl Platforms Clinical trial protocol design Clinical trial recruitment Social media insights & prediction platform & retention platform & methodologies Page 8
Slide 10: Clinical trial protocol design & prediction - Platform 1
Clinical trial protocol design & prediction - Platform 1 Goal: Improve design of clinical trials and success rates, and thus improve efficiency in execution and application of financial resources Objective: Use past clinical trial data (clinicaltrials.gov) natural language processing and 'explainabl
Slide 11: Platform 1 - Development overview
Platform 1 - Development overview Scheduled for market launch Q4 2021 Algorithm development systems model Stage 1 300,000 + clinical trials ingested MVP 4 stage development plan Currently in stage 3 of platform development Explainable AI to develop directional Accessing R&DTI Stage 2 variable insigh
Slide 12: Improving clinical trial design - evaluating protocol variables
Improving clinical trial design - evaluating protocol variables Enrolment - study_country_outside_top10country - number_of_sites_countries - Machine learning algorithm intervention_type_drug - provides indication of variable condition_classCo4 - importance phase - number_of_sites - Outcomes vary sig
Slide 13: Improving clinical trial design - an 'explainable' model
Improving clinical trial design - an 'explainable' model Uses emerging field of 'explainable' AI - insight into impact if a variable is adjusted during design phase Novel predictive modelling feature - significant value proposition, improving PoS Development of this feature is ongoing - currently 14
Slide 14: Clinical trial recruitment - Platform 2
Clinical trial recruitment - Platform 2 Goal: Improve recruitment to and retention in any registered clinical trial, in any global location, using artificial intelligence to match patients to trials based on volunteered health data. Objective: Design a system that uses social media as the funnel to
Slide 15: Platform 2 Recruitment - Development overview
Platform 2 Recruitment - Development overview Opyl services currently using social Currently generating revenue; media to recruit to trials Stage 1 next generation platform launch 2H 2021 Build initial client base Identify public data sources 3 stage development plan Stage 2 Design web-based platfor
Slide 16: Improving clinical trial recruitment - patient activated
Improving clinical trial recruitment - patient activated Patients self select and set filters to match their preferences Patients volunteer key health data related to trial eligibility Patient data is encrypted and stored Patient offered valuable information about relevant research study opportuniti
Slide 17: Improving clinical trial recruitment - social media as the funnel
Improving clinical trial recruitment - social media as the funnel Opyl services expertise designs targeting strategy via social media and creates all 'paid' content Revenue based on success model with modest up front project set up fee Opyl's existing services team have expertise in clinical trial r
Slide 18: Social media insights - Platform 3
Social media insights - Platform 3 Goal: To identify and utilise patient reported outcome measures and insights related to health shared to public social media, supporting marketing and sales objectives with health clients and in support of clinical trial recruitment Objective: Use a suite of propri
Slide 19: Social media insights and marketing services clients
Social media insights and marketing services clients Page 20
Slide 20: Summary
Outlook Summary Opyl targeting the $USD198Bn clinical trials market Launching 2 key digital platforms in 2021 - new revenue streams Opyl has clear market advantage through expertise in digital health marketing & AI Driving scalable business through existing and new platforms and services Scaling up