Renovacare, Inc. · OTC:RCAR
Renovacare — H.C. Wainwright Global Life Science Conference 2021
25 slides from Renovacare's conference presentation, Mar 11, 2021
Slide 1: SkinGun & CellMist Next Generation Ultra-Gentle Cell Spray
1 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 SkinGun™ & CellMist™ Next Generation Ultra - Gentle Cell Spray Symbol: RCAR H.C. Wainwright Global Life Science Conference Alan L. Rubino Chairman & CEO Robin A. Robinson, PhD Chief Scientific O
Slide 2: Forward-looking statements
2 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 This slide deck and the accompanying oral presentation contain forward - looking statements, including, but not limited to, statements related to RenovaCare Inc . ’s future financial and operati
Slide 3: RenovaCare: Past, Present, and Future
3 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 Development at StemCell Systems: SkinGun™ Cell Spray Device CellMist™ Cell Isolation Process Historical: Discovery Current: Clinical Future: Commercial Technology Evolution Company Focus Electro
Slide 4: Next-Generation Biomedical Technologies Devices & Products
4 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 Next - Generation Biomedical Technologies Devices & Products
Slide 5: Skin Grafting is Inefficient, Painful, Expensive, and Leaves Scarring
5 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 Skin Grafting is Current Standard - of - Care Painful & Lengthy Treatment Cycle Expensive, Drug Dependent Psychologically Damaging Sheets of meshed skin for surgical stitching Mesh scars in skin
Slide 6: The RenovaCare Cell Therapy Products
6 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 Spray Head Controller Disposable Spray Head (Sterilized, Single Use) Electronic Spray Device Sterile, Multi - Use Cell Isolation Device Closed, Automated Sterile Multi - Use CID Tissue Digestion
Slide 7: RenovaCare Cell Isolation & SkinGun Procedure
7 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 Step 1: Examine Wound/Harvest Donor Skin Tissue Performed bedside by the surgical burn team (15 min.) Step 2: Cell Isolation by Enzymatic Digestion in Cell Isolation Device Performed by burn tec
Slide 8: CellMist System & SkinGun: Clinical Experience
8 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 *Treated under special innovative practice approach at: Berlin - Brandenburg Center for Regenerative Therapies, Charité Berlin; an d under innovative practice approach at UPMC Medical Center, Pi
Slide 9: The CellMist System Advantages
9 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 CellMist™ uses donor tissue sample. RenovaCare CellMist ™ Split Thickness Skin Graft 10cm 2 donor sample Donor Skin Sample 10cm 2 Typical › Small donor skin sample taken under local anesthetic ›
Slide 10: RenovaCare Product Portfolio: Four Major Submissions for Approval
10 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 IDE/PMA 510(k) 510(k) 510(k) CellMist System™ Electronic SkinGun™ Autologous Skin Stem Cell Therapy for Burns POTENTIAL APPROVALS FROM 2020 - 2025 Disposable SkinGun™ Cell Spray Deposition Devi
Slide 11: Competitive Landscape of Skin Cell Therapies for Burn Wounds
11 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 Cell Isolation Device in the CellMist™ System by RenovaCare RenovaCare Electronic SkinGun™ Actual SkinGun™ Cell Spray ReCell™ System by Avita ReCell Mechanical Sprayer Actual ReCell Cell Spray
Slide 12: RenovaCare Milestones & Timelines
12 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 IDE Submit (7/6/20) IDE Cond. Approval (8/5/20) IDE Full Approval Safety & Feasibility Clinical Study (Manual Method) Enrollment Commencement 2Q21 Bridging Clinical Study (Automated Method) Enr
Slide 13: RenovaCare Product Pipeline
13 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 Gene - Based Cell Therapy for Epidermolysis Bullosa • Genetic replacement of collagen VII gene in EB patients • SkinGun Spray Device • King’s College (London) partner • Animal testing on - goin
Slide 14: Research. Development. Innovation.
14 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 Research. Development. Innovation.
Slide 15: RenovaCare R&D and Innovation Team
15 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 Bioengineering & Cell Biology Regenerative Medicine Medical Device Engineering and Prototyping Regulatory - Centric IP Driven Engineering QMS Support Documentation RenovaCare R&D and Innovation
Slide 16: Data-Driven Partners with an Unwavering Focus on Impact
16 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 R&D / QMS Clinical Manufacturing Regulatory Partners Enabling Clinical Pathway DATA - DRIVEN PARTNERS WITH AN UNWAVERING FOCUS ON IMPACT
Slide 17: RenovaCare IP Summary
17 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 RenovaCare IP Summary
Slide 18: Expanding Our Intellectual Property
18 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 Cell spray device developed Disposable SkinGun™ Encompass all types of cell tissues or organs Modular handheld spray device for cells Additional IP filings Electronic SkinGun™ IP tested and val
Slide 19: Building For Success Focused On Results
19 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 Building For Success Focused On Results
Slide 20: Experienced Leadership Team
20 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 BUSINESS DEVELOPMENT OPERATIONS REGULATORY R&D MANUFACTURING CLINICAL FULLY - INTEGRATED CAPABILITIES Alan L. Rubino CEO / President / Chairman Robert Cook Chief Financial Officer Dr. Robin Rob
Slide 21: Commercial Market Potential
21 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 $1B ~$600 - 700M ~$200 - 300M ~$2B in - patient burns severe second degree operation theater POTENTIAL TWO BILLION DOLLAR MARKET OPPORTUNITY WITHIN THE U.S. RenovaCare Regenerative Cell Therapi
Slide 22: 2020–2021 Milestones / Goals
22 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 Regulatory Priorities Planned Clinical Trials Corporate Development Activities Four Clinical Sites Selected: Q1 2020 Safety & Feasibility Clinical Study Start: Q2 2021 FDA IDE Submission: Jul 2
Slide 23: Financial Highlights
23 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 ~$240.22 Million Market Cap $8.7 Million Cash - on - Hand $8.6 Million Stockholders Equity Closing price on Feb, 26, 2021: $2.75 Financials as of September 30, 2020 RenovaCare, Inc. Symbol: RCA
Slide 24: Building Shareholder Value
24 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 Building Shareholder Value RenovaCare: Focused, Growing, Disciplined & Proven ▪ cell isolation and spray technologies ▪ stem cell therapies for acute and chronic wounds, including burns ▪ highl
Slide 25: Thank you
25 © 2021 RenovaCare Inc. All rights reserved. H.C. Wainwright Global Life Science Conference I March 2021 spray - on stem cells for rapid healing . SkinGun™ & CellMist™ Next Generation Ultra - Gentle Cell Spray Symbol: RCAR Thank you for your participation. RenovaCare Investor Forum RenovaCare, Inc
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