Trellus Health Plc · LSE:TRLS
Trellus Health — FY2024 Earnings Presentation
23 slides from Trellus Health's earnings presentation, June 2025
Slide 1: Unlocking the Power of Human Resilience in Healthcare
® Unlocking the Power of Human Resilience in Healthcare Trellus Elevate® — The Smarter, Scalable Solution for Patient Engagement and Adherence 2024 Annual Results Marla C. Dubinsky, MD Joy Bessenger Co-Founder and CEO Chief Financial Officer www.trellushealth.com
Slide 2: Disclaimer
Disclaimer • The information contained in these slides and the accompanying oral presentation (together, the “Presentation”) has been prepared by Trellus Health plc (the “Company”). The Presentation is subject to updating, completion, revision and amendment without notice and as such it may change m
Slide 3: Trellus Health: Purpose-Built for Scalable Impact
Trellus Health®: Purpose-Built for Scalable Impact Trellus Health® is a healthcare technology company transforming chronic condition management through a proprietary resilience platform that improves outcomes, reduces costs, and drives value across pharma, clinical trials, and health plans. Our Diff
Slide 4: 2024 Operational Highlights
2024 Operational Highlights Signed and launched first commercial-scale pilot with large US Health Plan (Q1) • Extended enrollment for large health plan beyond initial 6-month enrollment period Signed 2 licensing agreements with pharma for proprietary assessments and content (H1) Strengthened the Boa
Slide 5: Post Period Highlights
Post Period Highlights Signed and launched agreement with J&J to support a pilot across US to assess Trellus Elevate® to support patients with moderately to severely active IBD Renewed Pfizer licensing agreement Expanded and adapted resilience platform to new verticals Deepened and advanced pipeline
Slide 6: 2024 Financial Highlights
2024 Financial Highlights • Net cash of $2.5m 30 April 2025 (31 December 2024: $4.3m) with the Company’s cash runway extended into October 2025 • Adjusted EBITDA* loss of $7.2m, in line with management expectations (31 December 2023: $5.8m loss) with revenue in the year of $114k (30 June 2024: $50k;
Slide 7: Why the Current Chronic Condition Model Isn't Working
Why the Current Chronic Condition Model Isn’t Working: Driving Costs, Delays, and Dropouts High Disease Uncontrolled Reactive Condition Burden Medication Costs Management • Large healthcare spend on • 50% of specialty meds not • 30-50% dropout due to low chronic conditions taken as prescribed engage
Slide 8: Trellus Elevate: The Catalyst for Lasting Change
Trellus Elevate®:The Catalyst for Lasting Change + Proven Resilience Platform Closes the Mindset Gap Scalable Human + Tech Support Behavioral science-powered, Targets individuals’ attitudes, beliefs, Combines live coaching support + proactive, personalized - improving and behavioral risks to adheren
Slide 9: Trellus Elevate: The Catalyst for Lasting Change
Trellus Elevate®:The Catalyst for Lasting Change Resilience Target Negative Behaviors Negative Impact Emotional distress and rigid Low disease knowledge & Low Disease Acceptance thinking of illness non-adherence Catastrophizing & Frequent symptoms & lack Low Self-Regulation difficulty coping of foll
Slide 10: Multi-Billion Dollar Market Opportunity
Multi-Billion Dollar Market Opportunity Pharma Development and Pharma Commercial Health Plans Clinical Trials Patient Support and Digital Health Market Size Estimated Market Size Market Size $46B Today-$66B by 2030 $5-10B and growing $7.6B Today-$25B by 2032 Key Drivers Key Drivers Key Drivers • Esc
Slide 11: Delivering Results at Scale: The ROI of Resilience in Action
Delivering Results at Scale: The ROI of Resilience in Action Across Multiple Chronic Conditions Pharma Development and Pharma Commercial Health Plans Clinical Trials Patient Support and Digital Health ✓ Fixing Pharma’s Biggest ✓ Redefining Pharma ✓ More Than a Digital Tool—A Bottleneck Sponsored Pat
Slide 12: Building Sustainable and Scalable Revenue Models
Building Sustainable and Scalable Revenue Models Health Plan Pharma Patient Clinical Revenue Sector Support (PSP) Trials Upfront Implementation Fee Licensing Fee Monthly Management Fee Pay for Performance Fee Nimble, sustainable approach Significant long-term growth opportunities ® 12 © 2025 Trellus
Slide 13: How Trellus Elevate Bridges the Resilience Gap for Better Outcomes
How Trellus Elevate® Bridges the Resilience Gap for Better Outcomes Cognitive Behavioral Applied Positive Therapy (CBT) Psychology (APP) Deficits Model Strengths Model Distressed Population Healthy Population Reduces distress by Builds on personal changing negative strengths & positive emotions, eve
Slide 14: The ROI of Resilience: Reducing Utilization & Costs, Improving Patient Outcomes
The ROI of Resilience: Reducing Utilization & Costs, Improving Patient Outcomes 160 138 140 -71%* *Resilience program participants (n=184) had significantly greater reduction in ED and hospitalization than controls (n=201), (p=0001). 120 -65%** 100 Score >70 HIGH Resilience 80 +59% 74 72 -94%* 70 -6
Slide 15: How Trellus Elevate Identifies, Engages & Transforms High-Risk Patients
How Trellus Elevate® Identifies, Engages & Transforms High- Risk Patients Step 1 Step 2 Step 3 ✓Resilience Risk Assessment ✓Resilience Score Review ✓Human-led touchpoints ✓Predicts Hospitalizations ✓Health Challenge Insights ✓Weekly Resilience lessons ✓Identifies Resilience Barrier ✓Onboarding Suppo
Slide 16: Real-World Impact: How Trellus Elevate Improves Engagement, Confidence & Resilience
Real-World Impact: How Trellus Elevate® Improves Engagement, Confidence & Resilience High Engagement Improved Confidence Greater Resilience 16 ® © 2025 Trellus Health Inc. All Rights Reserved
Slide 17: Trellus Elevate: Strategy & Traction
Trellus Elevate®®:Strategy & Traction Go-To-Market Strategy Traction and Upcoming Milestones Key Customers & Growth Markets Key Partnerships Across Verticals Pharma Services and Distribution, Clinical Trial Johnson & Johnson (J&J) Services, Health Plan Sector Astra Zeneca & Pfizer Large US Health Pl
Slide 18: Trellus Health: A Resilient Approach to Closing the Gaps
® Trellus Health : A Resilient Approach to Closing the Gaps Massive Market Need 90% of healthcare costs driven by chronic conditions Resilience- Scalable Science-Backed Based Platform Proven Results Model Drives ↓ ED visits, ↓ Behaviorally engagement, hospitalizations, targeted, tech- ↓ steroid use
Slide 19: Thank you
® Thank you Marla Dubinsky, MD CEO and Co-founder mdubinsky@trellushealth.com Joy Bessenger CFO jbessenger@trellushealth.com Trellus Health 44 South Broadway, Ste 100 White Plains, NY 10601, USA Corporate Office: 1-800-866-4165 Member Support: 1-800-989-5503 www.trellushealth.com
Slide 20: The Minds behind the Mission: Trellus Health Board of Directors
The Minds behind the Mission: Trellus Health® Board of Directors Kevin L. Murphy, Jr. Traci Entel Brian Griffin Erik Lium, PhD Mike Salter Non-Executive Chairman Non-Executive Director Non-Executive Director Non-Executive Director Non-Executive Director Kevin is a seasoned healthcare Traci has 25 ye
Slide 21: Consolidated Income Statement
Consolidated Income Statement For the year ended 31 December 2024 YE 2024 YE 2023 $’000 $’000 Revenue 114 19 Employee expense (4,005) (3,902) Professional costs (598) (739) Other costs (3,538) (2,181) Operating Loss (8,027) (6,803) Depreciation and amortization 865 957 Share based payments 13 24 EBI
Slide 22: 2024 Balance Sheet & Cash
2024 Balance Sheet & Cash Consolidated Balance Sheet Consolidated Cash Flow As of 31 December 2024 As of 31 December 2024 YE 2024 YE 2023 y/e 2024 y/e 2023 $’000 $’000 $’000 $’000 Intangible assets 7,616 7,923 Cash used by operations (8,024) (6,803) Tangible assets 13 35 Purchase of tangible assets
Slide 23: The Minds behind the Mission: Trellus Health Executive Leadership
The Minds behind the Mission: Trellus Health® Executive Leadership Marla Dubinsky, MD Joy Bessenger, CFO Jamey Hancock, CTO Kathleen Williams, Chief Innovation Officer CEO and Co-Founder With over 18 years in life sciences, Joy is driven With over 20 years of experience across healthcare, With over