Slide 1: The Cardiovascular Device Company
For personal use only The Cardiovascular Device Company Premium non-invasive cardiovascular monitoring for global medical markets Rob Phillips Executive Chairman and Chief Executive Officer Investment overview August 2013
Slide 2: Disclaimer
Disclaimer For personal use only • This Investor Presentation contains confidential information regarding Uscom and its affiliates. The information contained in this Investor Presentation is believed to be reliable. No assurance is given as to the accuracy or completeness of such information This In
Slide 3: Introduction
Introduction For personal use only “The ability to innovate is the driving force behind growth in the medtech sector. The factors leading to innovation are complex. Innovation is an art and a skill.” MassMEDIC Medtech Innovation Survey 2013 3 The measure of life www.uscom.com.au
Slide 4: Strategic background
Strategic background For personal use only • Health care sector strong and rallying • Uscom develops and markets premium breakthrough cardiovascular products • Global majors cut costs since GFC – cutting R&D and new products • Global majors have big distribution channels requiring innovative product
Slide 5: Uscom
Uscom For personal use only Two breakthrough medical devices – real products, real science and real value • Validation - proven • Key regulatory – both products CE, FDA, TGA • Revenues – both products • Hypertension and Heart failure markets – established clinical needs 5 The measure of life www.usc
Slide 6: Our Business
Our Business For personal use only • Uscom (ASX: UCM) makes and sells two FDA/CE/TGA approved cardiovascular monitoring products – USCOM 1A and the Uscom BP+ • Uscom products - two core cardiovascular measurements of cardiac output and blood pressure. • USCOM – Cardiac Output • Customers are hospita
Slide 7: Ultra-Sound Cardiac Monitor (USCOM1A)
Ultra-Sound Cardiac Monitor (USCOM1A) For personal use only Non invasive, accurate, compact technology platform solution Accurate cardiac output Works with all other hospital equipment Cardiac stroke volume Systemic vascular Intuitive touch screen resistance Heart rate Real time data Left + right he
Slide 8: USCOM 1A Cardiac Monitor
USCOM 1A Cardiac Monitor For personal use only Status • Local manufacturing and distribution in place • Growing Key Opinion Leader support worldwide • Sector Leading Science - 350+ independent peer-review papers • Established brand protected by extensive long-term IP estate • Capital sale with stron
Slide 9: USCOM – Sector leading science
USCOM – Sector leading science For personal use only 350+ Peer reviewed publications and presentations Emergency, Pediatrics, Cardiac transplantation, Electrophysiology, Heart Failure, Emergency transport, Anesthesia, Liver transplantation, ICU, Septic shock, Pre- eclampsia, Pulmonary hypertension,
Slide 10: Using clinical data to drive 1A sales
Using clinical data to drive 1A sales For personal use only • Level one clinical data is expanding clinical acceptance and use • Supports marketing and sales and also expands product use Example • 6yr NSW study showing a 90% reduction in sepsis mortality rates using USCOM1A to change Hospital Practi
Slide 11: Cardiac monitoring market landscape
Cardiac monitoring market landscape For personal use only Worldwide market estimate Department Total beds* (US) ($15,000,1/10beds) Neonatal ICU 17,000 $51m Paediatric ICU 4,000 $12m Cardiac Surgery 10,000 $30m Adult ICU 50,000 $150m Total 80,000 $243m Assumptions • Global market = US market x 2 • $1
Slide 12: Uscom Central BP+ Monitor
Uscom Central BP+ Monitor For personal use only New Wave Supra-systolic Oscillometry Central Blood Pressure and Pulse Pressure Wave Analysis FDA, CE and Home or clinical use TGA approvals Touch screen Supra-systolic Central BP+ Results in 30 seconds Reliable and accurate No training required Central
Slide 13: Uscom Central BP+ Monitor
Uscom Central BP+ Monitor For personal use only Status • Acquired from Pulsecor June 2013 – Central Blood Pressure and PWA • Currently integrating regulatory, manufacturing and distribution into Uscom • Strong KOL interest and global support • Established brand protected by extensive long-term IP es
Slide 14: Central Blood Pressure? the New Gold Standard
Central Blood Pressure? For personal use only …….the New Gold Standard “central pulse pressure is more strongly related to vascular hypertrophy, extent of atherosclerosis, and cardiovascular events than is brachial blood pressure” Artery Research 2009;3: 125-7 Hypertension 2007;50:197-203 14
Slide 15: Pulsecor Acquisition Background
Pulsecor Acquisition Background For personal use only Rationale • Immediate and growing revenues ($26k 2012, $86k 2013, ? 2014) • Gives Uscom a strategic leadership position in premium cardiac monitoring • Multiple scientific, operational and strategic synergies • Product has 10yrs development and v
Slide 16: Business Model
Business Model For personal use only $ $ USCOM BP+ Licensing Unit Sales Unit Sales Licensing Subscription Strategic Distributors Distributors Strategic Partners Partners Support Education Academic 16 The measure of life www.uscom.com.au
Slide 17: Manufacturing and sales strategy
Manufacturing and sales strategy For personal use only Manufacturing • Currently all in-house with capacity to make 50 USCOM 1A’s per month • Establishing new low cost, high volume manufacturing strategy for BP+ • Potential international manufacturing partnerships to provide greater capacity and inf
Slide 18: Experienced management team
Experienced management team For personal use only Rob Phillips • Founder and inventor of the USCOM1A Executive Chairman & CEO • Raised multiple rounds of capital • Recognised leader and innovator in the field of non-invasive cardiovascular monitoring with multiple peer review papers • Detailed knowl
Slide 19: Shareholder and financial snapshot
Shareholder and financial snapshot For personal use only ASX ticker UCM Recent acquisition opens multiple near Market cap $12.6 million term revenue opportunities and product Shares on issue 68 million synergies. Cash @ 30 June 2013 $541k Unlisted options 6,287,500 In active strategic distribution a
Slide 20: UCM - Investment
UCM - Investment For personal use only UCM Share Price 20 18 16 14 12 10 8 6 4 2 0 2012 Jan 2012 vwap 2013 vwap 2014 vwap* Quality stock with strong growth opportunities in rallying health sector Unrecognised value following acquisition - opportunity for significant price re-alignment Tightly held –
Slide 21: Milestones – Building Real Value
Milestones – Building Real Value For personal use only ✓ • Patented USCOM concept ✓ • Built the USCOM device ✓ • Achieved global regulatory ✓ • Validated USCOM technology ✓ • Global sales and brand recognition ✓ • Widespread KOL support ✓ • 600 units world wide ($9.5m revenue total) ✓ • Standards of
Slide 22: Milestones – Building Real Value
Milestones – Building Real Value For personal use only ✓ • Consolidated operations - 2011 ✓ • partnership Controlled cash consumption - build toward global distribution 2012 ✓ • Build science to “must have” status – BUSH sepsis protocol ✓ • Two product Company – Pulsecor acquisition 2013 We are here
Slide 23: Use of Funds
Use of Funds For personal use only • BP+ transfer to Uscom • Product developments – software and interactivity • Preparation for volume Manufacturing • Regulatory and IP optimisation • BP+ sales and Marketing programme • Operating capital 23 The measure of life www.uscom.com.au
Slide 24: Risks
Risks For personal use only • Global medical markets unpredictable • Product development/regulatory slower and more costly than expected • Distribution slow to achieve revenue goals • Competitive risks • Patent breaches • Inadequate capital – time and money 24 The measure of life www.uscom.com.au
Slide 25: Summary and outlook
Summary and outlook For personal use only • Premium cardiovascular device company poised for global growth • Strategic strength in the cardiovascular monitoring space • Two platform technologies with significant unrecognised value • An established and stable business team with a global focus • Activ
Slide 26: Summary: Excellent Business
Summary For personal use only Excellent Business 26 The measure of life www.uscom.com.au
Slide 27: Thank you
For personal use only Thank you www.uscom.com.au
Slide 28: Appendices
For personal use only Appendices
Slide 29: Testimonials
Testimonials For personal use only “This machine is saving lives, there are no two ways about it.” Professor Brendan Smith, Anesthetist, Intensivist and Emergency Physician, N.S.W. Dept of Health, Australia “The USCOM device is a simple method of accurately and noninvasively measuring central circul
Slide 30: For personal use only
“This machine is thought to have saved Abbie’s life.” “There are no words to describe how we felt“ Abbie's mother Charlotte Pattison For personal use only h;p://news.bbc.co.uk/2/hi/uk_news/england/noEnghamshire/8525901.stm 30
Slide 31: For personal use only
“Central BP is the wave of the future“ Fox News For personal use only http://www.youtube.com/watch?v=9MfQ-OxtZcM 31
Slide 32: USCOM1A competitive advantages
USCOM1A competitive advantages For personal use only Rel Non- SV beat Method Manufacturer Technology +Rep invasive Simple Cost Portable to beat USCOM 1A Uscom Doppler ✓ ✓ ✓ ✓ ✓ ✓ BioZ Sonosite BioImpedance ✗ ✓ ✓ ✗ ✓ ✗ NiCOM Cheetah BioReactance ✗ ✓ ✓ ✗ ✓ ✗ Nexfin Bmeye APP ✗ ✓ ✓ ✓ ✓ ✗ CardioQ Deltex
Slide 33: IP - Adding value
IP -‐ Adding value For personal use only USCOM has significant value in patent protected IP USCOM BP+ 22 granted patents 34 granted patents 5 pending applications 4 registered trade marks Uscom Patent Report – June 2013 2 registered trade marks Uscom Patent Report – Oct 2012 Building a product pipe
Slide 34: Foundations for growth - Deep R&D pipeline
Foundations for growth - Deep R&D pipeline For personal use only Multiple future products - Small, Telemetric, Continuous, Portable, iPhone Apps, Combined products, Uscom BP+ 34
Slide 35: Foundations for growth – new business
Foundations for growth – new business For personal use only USCOM Patient Telemetry Cloud Clinician Data 35 The measure of life www.uscom.com.au
Slide 36: Using clinical data to drive sales
Using clinical data to drive sales For personal use only National ICU Study and Result Hospital sepsis mortality review. 30 Bathurst USCOM NSW 25 NSW Rural Australia 20 Australian Rural 15 10 5 0 2006 2007 2008 2009 2010 2011 2012 Smith BE, Phillips RA, Madigan V, West MJ. Decreased Mortality, Morbi