Incyte Corporation · NASDAQ:INCY

Incyte — Q2 2026 Earnings Presentation

59 slides from Incyte's earnings presentation, Jul 28, 2026

  1. Slide 1: Global Responsibility Report 2025

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Global Responsibility Report 2025 2025 Global Responsibility Report | 1

  2. Slide 2: Table of Contents

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Table of Contents 03 06 20 23 33 42 49 Introduction Patients and Community People Environment Governance Appendix About This Report Innovation Incyte Charitable Giving Collaborative Culture Envi

  3. Slide 3: About This Report; About Incyte

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix About This Report Our annual Global Responsibility Report details progress of our environmental, social and governance (ESG) efforts and reflects our use of rigorous science to discover, develop

  4. Slide 4: Message from the CEO

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Message from the CEO I am pleased to share Incyte’s 2025 This work carries a responsibility—to uphold the highest standards of quality, Our Global Global Responsibility Report. Since safety and

  5. Slide 5: 2025 Highlights

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix 2025 Highlights IMPACTING PATIENTS WORLDWIDE A RECOGNIZED LEADER Over 400,000 ~280,000 5+ global 8 patients treated with medicines commercialized by Incyte patients assisted through U.S. patient

  6. Slide 6: Patients and Innovation

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Patients and Innovation With patients at the center of everything we do, our discovery approach focuses on building a scientifically differentiated portfolio designed to make a meaningful impact

  7. Slide 7: Focused Portfolio

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Focused Portfolio At Incyte, we recognize the transformative power of research to drive scientific innovation and shape the future of medicine. Our portfolio is organized around three core franc

  8. Slide 8: Clinical development pipeline

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Clinical development pipeline THERAPEUTIC AREA PROGRAM INDICATION(S) CLINICAL PROOF OF CONCEPT PIVOTAL Axatilimab 1L cGvHD (+ ruxolitinib) CSF-1R Hematology 1L cGvHD (+ steroids) CALR-mutated ET

  9. Slide 9: Partnerships

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix PARTNERSHIPS We continuously push the boundaries of scientific discovery in treatment development, recognizing that collaboration is key to unlocking the full potential of our science. By cultiv

  10. Slide 10: Clinical Trials

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Clinical Trials Clinical trials are essential to developing medicines that can meaningfully improve patient outcomes. 137 21 We conduct trials to evaluate treatment impacts and rely on volunteer

  11. Slide 11: Clinical Trial Transparency, Patient Engagement and Diversity

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Clinical Trial Transparency to engage trial participants and their caregivers, pediatric and adolescent space to ensure these diversity readiness, laying the groundwork for offering tools and co

  12. Slide 12: Protecting Patient Safety and Product Quality

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Protecting Patient Safety and Product Quality Protecting patients is at the core of what we do assessing and managing safety risks across the and requires both a strong pharmacovigilance product

  13. Slide 13: Product Quality; Supply Chain Security and Product Integrity

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Product Quality Incyte maintains a defined management Because GxP activities we outsource directly All commercial product packs are marked with a escalation process for quality events and affect

  14. Slide 14: Access to Medicine

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Access to Medicine We aim to ensure Incyte’s medicines are Access to Approved Medicines Increasing Global Patient Access accessible to eligible patients who need them. ~280,000 For investigation

  15. Slide 15: Patient Education and Awareness

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Patient Education and Awareness Patient Support Resources (U.S.) Patients living with diseases in Incyte’s focus areas often face challenges accessing information and connecting with others who

  16. Slide 16: 2025 Patient Education and Awareness Highlights

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix 2025 Patient Education and Awareness Highlights Hematology THE MPN VISUALAIZER As an extension of The Unseen Journey program, the Outside of the U.S., Incyte also convened an advisory MPN Visual

  17. Slide 17: Oncology

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Oncology ANAL CANCER AND SQUAMOUS CELL ANAL CARCINOMA (SCAC) In 2025, Incyte launched Analcancer.com, a 10.4M people and inspired more than 423,000 highlights that while many people understand w

  18. Slide 18: The Power of Choice with Winnie Harlow

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Inflammation & Autoimmunity (IAI) EXPANDING THE INCYTE INGENUITY AWARDS TO HIDRADENITIS SUPPURATIVA (HS) In 2025, Incyte launched the Incyte Ingenuity to $100,000. Applications will be evaluated

  19. Slide 19: Patient Advocacy

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Patient Advocacy Incyte partners with patient advocacy organizations to address unmet patient In 2025, the U.S. MAY AUGUST needs, close education gaps and develop Oncology Eight anal cancer pati

  20. Slide 20: Community

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Community Incyte is on a mission to Solve On and caring for others shapes how we bring that mission to life, starting with our employees and extending to the patients, caregivers and communities

  21. Slide 21: Incyte Charitable Giving Foundation

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Incyte Charitable Giving Foundation The Incyte Charitable Giving Foundation (“the Foundation”) helps make a difference in our Delaware communities, especially in Wilmington, home to our global h

  22. Slide 22: Community Service Program; Matching Gifts Program

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Community Service Program Giving back is part of our culture, and we encourage our employees to make a difference in their communities. Through our Community Service Program, we offer all employ

  23. Slide 23: People

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix People At Incyte, every employee plays a role in advancing solutions that improve the lives of patients, many of whom are waiting for solutions that cannot come fast enough. That urgency shapes

  24. Slide 24: Awards and Recognition

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Our Employees Gender Diversity Geographic Location 975 70% 940 Sales and marketing 1,456 Research and 1,364 United States development 716 Women Men and Canada General and administrative 27% 213

  25. Slide 25: A Collaborative Culture

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix A Collaborative Culture At Incyte, innovation is not confined to a function or a role, it is a shared responsibility. From our newest hires to our Executive Leadership Team, we believe the best

  26. Slide 26: Professional Development

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Professional Development Career growth at Incyte is collaborative, newly hired and recently promoted managers cross-functional collaboration, while also intentional, continuous and employee-driv

  27. Slide 27: Performance Management; Internal Mobility and Career Growth

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Performance Management This supportive and collaborative approach University in Philadelphia, Pennsylvania to to performance management enhances the sponsor a two-year fellowship in Medical Incy

  28. Slide 28: Compensation and Benefits

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Compensation and Benefits We are committed to providing competitive compensation and comprehensive benefits that enable every Incyte employee to thrive both professionally and personally. Our to

  29. Slide 29: Enhancing Flexibility and Well-being

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Benefits Enhancing Flexibility We offer comprehensive benefits that support the needs and well-being of our global workforce. We take a data-driven approach to evaluating and enhancing our offer

  30. Slide 30: Inclusion

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Inclusion Developing best-in-class solutions for our patients requires a collaborative, innovative and Gender (Global) 51% 33% inclusive culture. Our merit-based hiring process As of December 31

  31. Slide 31: Safety and Wellness

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Safety and Wellness At Incyte, every employee and contractor shares international standards and best practices. Our 2022 2023 2024 2025 responsibility for reducing risk, preventing injuries inci

  32. Slide 32: EHS Training; Emergency Preparedness; Well at Work

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix EHS Training We provide safety training as part of employee onboarding. Laboratory and manufacturing employees receive job-specific instruction covering potential hazards, including proper waste

  33. Slide 33: Environment

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Environment As an industry leader that understands the profound connection between environmental integrity and public health, our commitment to patient well-being includes setting robust environ

  34. Slide 34: Environmental Targets and Progress

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Environmental Targets and Progress As Incyte expands globally, we are focused Target Progress on minimizing our environmental impact and Achieve operational carbon neutrality by We continue to r

  35. Slide 35: Environmental Oversight

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Environmental Oversight Incyte’s full Board of Directors provides oversight of our ESG strategy, including targets and initiatives designed to reduce our environmental impact. Specific Board Com

  36. Slide 36: Emissions Reduction

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Emissions Reduction 12 Since establishing our 2019 baseline, we’ve taken meaningful steps to reduce absolute Scope 1 and 2 emissions, even as our square footage, employee headcount and revenue 2

  37. Slide 37: Scope 1 and Scope 2 Emissions

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Scope 1 and Scope 2 Emissions13 Metric 2019 2023 2024 2025 Scope 1 emissions (MTCO2e) 4,775 9,351 9,576 8,872 Scope 2 emissions (Location-based) (MTCO2e) 7,450 6,079 6,516 6,709 Total Scope 1 &

  38. Slide 38: Energy Reduction at our Facilities

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Energy Reduction at our Facilities Energy Consumption – Buildings Only14 As of April 2026, our owned facilities account for approximately 70% of our total square footage. While these sites repre

  39. Slide 39: Emissions Offsets; Scope 3 Emissions; Green Initiatives

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Emissions Offsets 15 SCOPE 3 EMISSIONS CATEGORIES 16 Reducing our carbon footprint is our primary focus, with carbon credits serving as a complementary Metric 2019 2023 2024 2025 tool to achieve

  40. Slide 40: Water Conservation

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Water Conservation Across our global footprint, we strive to conserve We comply with local regulations for wastewater water. All new and renovated spaces are permitting and handling, submitting

  41. Slide 41: Waste Management

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Waste Management Incyte is committed to reducing waste and fuel-blended or otherwise disposed of at a facility Waste Metrics (Metric Tons)24, 25 managing it responsibly in accordance with all ov

  42. Slide 42: Governance and Risk Management

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Governance and Risk Management Strong ethics and good governance are fundamental to creating both long-term value for our shareholders and broad positive impacts for our patients, employees, com

  43. Slide 43: Corporate Governance

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Corporate Governance We believe engaged directors with diverse backgrounds are critical for effective oversight. ESG Oversight Our Board members bring a wealth of scientific knowledge, extensive

  44. Slide 44: Responsible Research and Development

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Responsible Research and Development At Incyte, we take seriously our responsibility to patients, employees, shareholders and the biomedical research community. Maintaining high ethical standard

  45. Slide 45: Ethics and Compliance Program

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Ethics and Compliance Program Incyte implements a comprehensive Compliance Program that helps us maintain easily accessible written standards, provide ongoing education and training, conduct ris

  46. Slide 46: Ethics and Compliance Training; LC eGuide Launch

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Ethics and Compliance Training and Resources LC eGuide Launch We clearly communicate our ethical standards During Corporate Compliance & Ethics Week in 2025, we reinforced our commitment to inte

  47. Slide 47: Ethical Marketing; Human Rights

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Ethical Marketing Human Rights To ensure practitioners and patients can guidelines. Employees in promotional roles receive At the core of Incyte’s purpose to find solutions and the International

  48. Slide 48: Cybersecurity and Data Privacy; Our Approach to Tax

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Cybersecurity and Data Privacy Our Approach to Tax We honor the relationships we’ve built with partners. Incyte has not been required to report a As a biopharmaceutical company, we have Responsi

  49. Slide 49: Appendix

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Appendix 2025 Global Responsibility Report | 49

  50. Slide 50: UN SDGs; TCFD

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix UN SDGs on our business strategy and financial planning information technology risks. Within these risks, that may become more frequent due to climate for the future. Each year, we strive to enh

  51. Slide 51: TCFD Strategy

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix STRATEGY At Incyte, we have a well-defined strategy Following our initial climate risk evaluation, we focused on addressing critical unmet medical performed an updated climate risk assessment ne

  52. Slide 52: Transition Risks

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Transition Risks RISK TYPE CLIMATE-RELATED RISK TIME HORIZON (S, M, L) RISK IMPACT MITIGATION Policy and Legal Enhanced reporting obligations due to climate S, M Expenditures - Increased operati

  53. Slide 53: Transition Risks (Market)

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Transition Risks RISK TYPE CLIMATE-RELATED RISK TIME HORIZON (S, M, L) RISK IMPACT MITIGATION Market Increased cost and disruption to raw materials S, M, L Expenditures - Increased operating exp

  54. Slide 54: Physical Risks

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Physical Risks RISK TYPE CLIMATE-RELATED RISK TIME HORIZON (S, M, L) RISK IMPACT MITIGATION Acute Increased severity and frequency of flooding M, L Expenditures – Increased direct and indirect c

  55. Slide 55: Climate-related Opportunities

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Climate-related Opportunities OPPORTUNITY TYPE CLIMATE-RELATED OPPORTUNITY TIME HORIZON (S, M, L) OPPORTUNITY IMPACT MANAGEMENT Energy resource Use of lower-emission sources of energy S, M, L Ex

  56. Slide 56: Climate Resilience: Impact on Strategy & Financial Planning

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix Climate Resilience: Impact on Strategy also make clinical trial sites inaccessible or delay Low-Warming Future (<2°C) global healthcare innovation and help sustain & Financial Planning patient v

  57. Slide 57: Risk Management

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix RISK MANAGEMENT potential impacts at each of our locations under gas emissions, energy use, water consumption Our risk assessment processes allow us to a carbon-intensive scenario (aligned with

  58. Slide 58: SASB

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix SASB Accounting Metric Code Disclosure Accounting Metric Code Disclosure Safety of Clinical Trial Participants Counterfeit Drugs Discussion, by world region, of management process for ensuring q

  59. Slide 59: Introduction Patients and Innovation Community

    Introduction Patients and Innovation Community People Environment Governance and Risk Management Appendix © 2012-2026 Incyte 2025 Global Responsibility Report | 59

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