Hyperfine, Inc. · NASDAQ:HYPR
Hyperfine — Investor Presentation (February 2025)
35 slides from Hyperfine's investor presentation, Feb 11, 2025
Slide 1: AI-Powered, Portable Brain MRI Corporate Investor Deck
Exhibit 99.1 AI-Powered, Portable Brain MRI ® ® The Swoop Portable MR Imaging system is driving the future of brain health. Corporate Investor Deck Hyperfine, Swoop, and Portable MR Imaging are registered trademarks of Hyperfine, Inc. PROPERTY OF HYPERFINE, INC. ©2025. All rights reserved. PROPERTY
Slide 2: Forward-looking Statements
Forward-looking Statements This presentation includes “forward-looking statements” within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Actual results of Hyperfine, Inc. (the “Company”) may differ from its expectations, estimates and projections
Slide 3: Leadership Team With Proven Track Record of Success
Leadership Team With Proven Track Record of Success Maria Sainz Dave Castiglioni President and Chief Chief Commercial Officer Executive Officer Brett Hale Chi Nguyen Chief Administrative Vice President of Officer and Chief Office Strategy and Financial Officer Partnerships Tom Teisseyre, PhD Rafael
Slide 4: The Portable Swoop System Serves Patients and Clinicians Where and When They Need Brain Imaging
The Portable Swoop System Serves Patients and Clinicians Where and When They Need Brain Imaging 1 Diagnostic-quality images Broad FDA-clearance for brain with ultra-low-field MRI imaging of patients of all ages First mover with proprietary Commercially available in the technology (150+ patents) US t
Slide 5: Sizeable and Growing U.S. Total Addressable Market Opportunity
Sizeable and Growing U.S. Total Addressable Market Opportunity 1 Expanding TAM Through New Sites of Care & New Clinical Applications $1.5B $6B+ $16B+ 2026+ 2024+ 2025+ Beachhead Large Neuro Market Brain Health 2 5,600 emergency departments 10,700 urgent care facilities 4,000 critical care units 2,40
Slide 6: Multiple & Diverse Anticipated Growth Catalysts
Multiple & Diverse Anticipated Growth Catalysts Broad Indication & Versatile Technology Expected to Drive New Market Entrance and Adoption 2024 2025 Today US Critical Care: Continued Expansion New Outpatient Market Entry Site of Care and Use Case Drivers SITE OF CARE & USE CASE Emergency Department
Slide 7: Growth Catalysts De-Risked by Recent Milestones
Growth Catalysts De-Risked by Recent Milestones 2024 2025 Today US Critical Care: Continued Expansion New Outpatient Market Entry Site of Care and Use Case Drivers SITE OF CARE & USE CASE Emergency Department Entry ACTION PMR Data (Stroke) Stroke Workflow Study EXPANSION Hospital Based Clinic Entry
Slide 8: Innovation: Fast Cadence of AI-Powered Software Releases
Innovation: Fast Cadence of AI-Powered Software Releases to Drive Image Quality Performance ... 2024 Software (8.8): Faster imaging Software (8.7): AI denoising in DWI sequence 2023 Software (8.6): DWI improvements, motion correction Software (8.5): Improved DWI image quality, intensity AI-powered I
Slide 9: Image Quality Approaching High Field
Image Quality Approaching High Field Hyperfine has Rapidly Accelerated the Clinical Utility of Portable Ultra-low field MRI Illustrative Image Quality Improvements with FLAIR Contrast: pULF workhorse th th 1 First FDA Clearance 8 Generation SW Next Gen (10 ) SW Q1 2020 Launched Q1 2024 Expected 1H 2
Slide 10: Solid Financial Fundamentals
Solid Financial Fundamentals 2 Revenue and Gross Margin Cash Burn 2 Year Revenue CAGR +38% $71.0 Service Revenue 46% $20.0M 80% 43% 13% Device Revenue 30% $42.3 $15.0M $12.9M YoY $38.4 (20%) Gross Margin (%) $11.0M Growth -78% YoY $2.4M +17% Growth $10.0M (70%) $2.3M +62% $6.8M -162% (120%) $1.6M $1
Slide 11: Transformation of Business Poised to Drive Growth Acceleration
Transformation of Business Poised to Drive Growth Acceleration From Multiple Catalysts • Transformation Launched in Q4’24 Revenue Transformation From Research to Organic Commercial • 2025+ Expansion Strategy Is Aggressively Pursuing New 15 Markets $12.9 13 • Initial Commercialization Through 2024 dr
Slide 12: Appendix
Appendix February 2025 Corporate Investor Deck 12 PROPERTY OF HYPERFINE, INC. ©2025. All rights reserved.
Slide 13: Who is Hyperfine?
Who is Hyperfine? First FDA-cleared, portable MR brain imaging system with proprietary AI technology, a proven track record of innovation, broad labeling, and existing reimbursement Platform technology reshaping the care paradigm and expanding the brain imaging It feels market globally to address la
Slide 14: A First for Brain Health
A First for Brain Health Hyperfine, Inc. has a unique ultra-low-field portable MR brain imaging system that aims to improve brain health globally. • Designed to improve access, equity, and affordability for clinicians and patients • Expands brain MR imaging to multiple professional healthcare settin
Slide 15: MRI is the Clinical Gold Standard
MRI is the Clinical Gold Standard Capacity and Availability of Conventional MRI Compromise Access and Equity Globally High-cost and complex site requirements limit access Need for highly trained personnel constrains capacity Limited availability leads to delayed diagnosis and care Inpatient transpor
Slide 16: The Portable Swoop System Serves Patients and Clinicians Where and When They Need Brain Imaging
The Portable Swoop System Serves Patients and Clinicians Where and When They Need Brain Imaging 1 Diagnostic-quality images Broad FDA-clearance for brain with ultra-low-field MRI imaging of patients of all ages First mover with proprietary Commercially available in the technology (150+ patents) US t
Slide 17: A New Paradigm in the Economics, Value, and Safety of Brain Imaging
A New Paradigm in the Economics, Value, and Safety of Brain Imaging Conventional MRI Swoop System CT Scanner Low Up-front Capital No Construction or Installation Required Minimal Recurring Costs No Need for Certified Operators Limited Staff Disruption Portable Soft Tissue Characterization Patient Sa
Slide 18: The Swoop System is Transforming Brain Imaging
The Swoop System is Transforming Brain Imaging Safe for clinicians, patients, and Portable through standard doors Intuitive iPad-based interface caregivers across multiple sites of care and elevators 18 PROPERTY OF HYPERFINE, INC. ©2025. All rights reserved.
Slide 19: Blueprint for Anticipated Growth
Blueprint for Anticipated Growth The Swoop System Designed to Expand the Global Imaging Market to Increase Access and Equity 2026+ Brain Health 2025+ Large Neuro Market 2024+ Primary Care / Community Beachhead ED / Clinics / Offices Hospital Remote Care Critical Care Alzheimer's Pediatrics Stroke We
Slide 20: Sizeable and Growing U.S. Total Addressable Market Opportunity
Sizeable and Growing U.S. Total Addressable Market Opportunity 1 Expanding TAM Through New Sites of Care & New Clinical Applications $1.5B $6B+ $16B+ 2026+ 2024+ 2025+ Beachhead Large Neuro Market Brain Health 2 5,600 emergency departments 10,700 urgent care facilities 4,000 critical care units 2,40
Slide 21: Multiple & Diverse Anticipated Growth Catalysts
Multiple & Diverse Anticipated Growth Catalysts Broad Indication & Versatile Technology Expected to Drive New Market Entrance and Adoption 2024 2025 Today US Critical Care: Continued Expansion New Outpatient Market Entry Site of Care and Use Case Drivers SITE OF CARE & USE CASE Emergency Department
Slide 22: Drive Adoption In Emergency Departments - Acute Ischemic Stroke
Drive Adoption In Emergency Departments - Acute Ischemic Stroke Triage Use Case Stroke Detection Sequence Optimization & AI Market Adoption • ACTION-PMR, is a multi-center • Software & sequence optimizations • Begin placement of Swoop units in evaluation to assess the use of / updates emergency depa
Slide 23: Drive Adoption In Neurology Office
Drive Adoption In Neurology Office Right to Play & Office Business Model Market Adoption Clinical Evidence • IAC Accreditation standards • Refine & optimize sales and • Begin placement of Swoop units published November 2024 now support business model in neurology clinics include ultra-low-field MRI,
Slide 24: IAC Standards Published in Nov 2024 Opens Office Market Opportunity
IAC Standards Published in Nov 2024 Opens Office Market Opportunity Intersocietal Accreditation Commission (IAC) • 1 of 4 CMS-approved accreditation bodies • Offices that get IAC accreditation are immediately eligible for CMS reimbursement New standards Incorporating Portable MRI • Standards include
Slide 25: Execution: Three Focus Areas & Spending Discipline
Execution: Three Focus Areas & Spending Discipline Innovation Commercialization Clinical Evidence 25 PROPERTY OF HYPERFINE, INC. ©2025. All rights reserved.
Slide 26: Innovation: Fast Cadence of AI-Powered Software Releases
Innovation: Fast Cadence of AI-Powered Software Releases to Drive Image Quality Performance ... 2024 Software (8.8): Faster imaging Software (8.7): AI denoising in DWI sequence 2023 Software (8.6): DWI improvements, motion correction AI-powered Imaging Software (8.5): Improved DWI image quality, int
Slide 27: Image Quality Approaching High Field
Image Quality Approaching High Field Hyperfine has Rapidly Accelerated the Clinical Utility of Portable Ultra-low field MRI Illustrative Image Quality Improvements with FLAIR Contrast: pULF workhorse th th 1 First FDA Clearance 8 Generation SW Next Gen (10 ) SW Q1 2020 Launched Q1 2024 Expected 1H 2
Slide 28: Clinical Evidence: Large & Growing Body of Published Data
Clinical Evidence: Large & Growing Body of Published Data to Support Adoption Studies to Drive Evidence in New Use Cases Current Commercial Clinical Research Future and Clinical Applications for Future Applications Opportunities Advisory Groups Pilot Programs User Groups Critical Care Pediatrics Str
Slide 29: Commercialization: Scalable US Direct Sales & Global Distribution Network
Commercialization: Scalable US Direct Sales & Global Distribution Network Commercial Profile • Upfront and Recurring Revenue Model • Multiple Placement Potential per Customer • Flagship Reference Institutions in Adult and Pediatric Care Installed Base Health Economics Over 175 Swoop 1 • Existing Rei
Slide 30: System Economics Provide Attractive Margin Expansion Opportunity
System Economics Provide Attractive Margin Expansion Opportunity Strong Margin Foundation with Healthy U.S. Pricing and Recurring Revenue Recurring Revenue Expected to Increase with Growth in Placements & Installed Base---------------à Year 1 Years 2 – 5 INITIAL Annual Recurring Revenue (Software &
Slide 31: Solid Financial Fundamentals
Solid Financial Fundamentals 2 Revenue and Gross Margin Cash Burn 2 Year Revenue CAGR +38% $71.0 Service Revenue 46% $20.0M 80% 43% 13% Device Revenue 30% $42.3 $15.0M $12.9M YoY $38.4 (20%) Gross Margin (%) $11.0M Growth -78% YoY $2.4M +17% Growth $10.0M (70%) $2.3M +62% $6.8M -162% (120%) $1.6M $1
Slide 32: Illustration of Potential Revenue Opportunity Based on TAM
Illustration of Potential Revenue Opportunity Based on TAM $100M US Swoop Device Revenue For Every 1.5% Market Penetration (1) Illustration of Potential US Device Revenue With Site Penetration Growth (Beachhead and Neuro Market Only) Market Entry Hurdles Cleared Potential $400M Reimbursement Selling
Slide 33: Leadership Team With Proven Track Record of Success
Leadership Team With Proven Track Record of Success Maria Sainz Dave Castiglioni President and Chief Chief Commercial Officer Executive Officer Brett Hale Chi Nguyen Chief Administrative Vice President of Officer and Chief Office Strategy and Financial Officer Partnerships Tom Teisseyre, PhD Rafael
Slide 34: The Hyperfine, Inc. Opportunity
The Hyperfine, Inc. Opportunity First FDA-cleared portable Growth blueprint driven by expanding ultra-low-field AI-powered MR brain to new sites of care; emergency imaging system with strong departments, clinics and offices, new proprietary technology geography and sustained innovation Commercial st
Slide 35: Hyperfine, Swoop, and Portable MR Imaging are registered trademarks of Hyperfine, Inc. 35 PROPERTY
Hyperfine, Swoop, and Portable MR Imaging are registered trademarks of Hyperfine, Inc. 35 PROPERTY OF HYPERFINE, INC. ©2025. All rights reserved. PROPERTY OF HYPERFINE, INC. ©2025. All rights reserved.