Niagen Bioscience, Inc. · NASDAQ:NAGE

Niagen Bioscience — ChromaDex — Q1 2021 Earnings Presentation

23 slides from Niagen Bioscience's earnings presentation, May 6, 2021

  1. Slide 1: Earnings Conference Call First Quarter 2021

    TRU NIAGEN ChromaDex Earnings Conference Call First Quarter 2021 Rob Fried Chief Executive Officer Frank Jaksch Co-Founder / Executive Chairman Kevin Farr Chief Financial Officer Nasdaq: CDXC | May 6, 2021 1

  2. Slide 2: S croman TRUNIAGEN

    S croman TRUNIAGEN

  3. Slide 3: Q1 2021 & Recent Highlights

    Q1 2021 & Recent Highlights Tru Ni sequent sn net sales up 12% and total company up 2% YoY. Tru Niagen® net sales up 1% and total company down 5% lly. Supply chain disruptions impacted Watsons’ shipments, which are expected to normalize in Q2 and Q3. Net loss was ($7.4) million or ($0.12) per share,

  4. Slide 4: Management Team

    Management Team TRU NIAGEN

  5. Slide 5: Scientific Update

    Scientific Update

  6. Slide 6: Scientific Advisory Board

    Scientific Advisory Board

  7. Slide 7: Most prominent human clinical research areas for Niagen

    Most prominent human clinical research areas for Niagen® are vitality, locomotion, cognition, and sensory ‘sexe fees pa Tega us Cogn moment “ecco concen Caceres | Aimar Outen Sma a Fi noon, Nemec Fat ne” tac Franson Woetons sweiena rene ay Oana wen: adc Nag? WB leech oad Conse a an vat ade 8 wages n

  8. Slide 8: NR Research Impact is Accelerating

    NR Research Impact* is Accelerating = = @ & ‘Basic Research ‘Cumulative impact Factor eRe monty domains tines Cass 2013 2014 2015-2016 2017208 201920202024

  9. Slide 9: Science Continues to Expand

    Science Continues to Expand + Two new human stud ‘on nicotinamide riboside registered since prior update: ‘+ Massachusetts General Hospital and Harvard Medical School (March 2021) ‘+ The objective is to investigate the impact of NR supplementation in 100 patients with persistent cognitive and physic

  10. Slide 10: Financial Highlights

    Financial Highlights

  11. Slide 11: Q1 2021 Net Sales Mix

    Q1 2021 Net Sales Mix Q1 2020 12021 $14.3MM * $14.7MM “— _ vt gent ‘tne ngs, seonandenoee as > Tru Niagen® net sales increased to 85% of net sales in Q1 2021 compared to 80% in Q4 2020 > Niagen®-related net sales decreased to 93% of net sales in Q1 2021 compared to 94% in Q 2020 °) Higher mix of Tru

  12. Slide 12: Q1 2021 Net Sales

    Q1 2021 Net Sales Q1 2021 Net Sales Growth Rates (6 in millions) YoY % 00 % (ws 2020)—_(vs.042020) wore aone oro I 2° nn heen reat! 08 ‘Standards 8 Services (1) Other ingredients | 0.1

  13. Slide 13: 2018 — 2021 YTD Net Sales Summary

    2018 — 2021 YTD Net Sales Summary 993) 399 33° 995 Pe PE 289) 335

  14. Slide 14: Q1 2021 vs Q4 2020 Key P&L Metrics

    Q1 2021 vs Q4 2020 Key P&L Metrics (eo emande) Pat zoat | atzoe0 [notes Tru Nagen® business up 1% seven by gabal e-Commerce and Net Sates sages sasaas_— einen ces, oy ey ve een Sslesowerance nlangesoing 9 Thome. ‘Up 1800p erivenby predict cost savings inten, ver sal Gross Profit 9.234 ton supp ena o

  15. Slide 15: Q1 2021 vs Q1 2020 Key P&L Metrics

    Q1 2021 vs Q1 2020 Key P&L Metrics “Tru Nagon® bunness up 12% wth roan n ebal ecommerce andtecenttematonaaunehes. Watsons sales down sgh) Netsaies $1445 Given by COVID-19 supp chan eruptions and chalengg por Ig ear compare (eta snpsinfrTruNlagen® Beauty inst) Gross Profit tant Seling and Marketing N

  16. Slide 16: Adjusted EBITDA Summary

    Adjusted EBITDA Summary Reconciliation of Non GAAP Financial Measures (thousands) War Si, Wn30, Sep 30, Dee 3H, | Mardi, an 30, Sop 30, Owe 3H, | Mah zoo “zoi_t019" 2010" | “2020' _“20m0' “20002000 | 2024 Netios, a reported 5 33 $ @.788) $0202) $ easy |s 69) s a7 $4218) $ (os |s Cae “Adusets ‘ree (r

  17. Slide 17: Q1 2021 Operating Loss vs Q1 2020

    Q1 2021 Operating Loss vs Q1 2020 TRU NIAGEN

  18. Slide 18: Quarterly Balance Sheet Highlights

    Quarterly Balance Sheet Highlights Ge 23s | xciie| sain | sooo | enzo | rasico | att | Key Driver 525 mln eaptlrase plus $2261 $1mei2 515008 $10.800 515.478 | SHEET | $4460 sock optoncnercney employees 1230811001 RES) 12.702 _lovosmeniato support Sos 3208 | 264 | 4647 sales nating ot 52i8 5.73 | 6AB

  19. Slide 19: Quarterly Cash Flow Highlights

    Quarterly Cash Flow Highlights (thousands) Fy 2018 | FY 2019 9730720 S069) $@7) $4218) —_$(6.007) $0620) $528 saat S219 Sars 13600 s1ms90 ssaTe 16697 Investments to grow the business and protect our IP, while tightly managing working (been tn tres ten er payee a Nes {2 nove tomar asses comets rie me

  20. Slide 20: 2021 Financial Outlook

    2021 Financial Outlook Contnued sendy revenue growth, + Glabsl e-Commerce business ‘wen acelerata grontnin G2 2021 | Exstng + new evatege partnerships Net Stee sez s80257 ‘Gross Margin % 57% (8a Kotnet aos) ‘Seling, Marketing & Advertising 394% 384% Up sghty an 0% of net sales (asa otnet sates) Rese

  21. Slide 21: Adjusted EBITDA 2019 vs 2020

    Adjusted EBITDA 2019 vs 2020 Chromabex Corporation and Sass (nttowsend) Vearended Year oer Yor Neth a sep Inet eee n Dacca oy Amer fangs ea) ‘Amount gif we sete » ‘Saretunedconpemat ron Seven and eretng 1790 vamebiod tad St perc : Adel EBEIDA z Tag Tealepeageme as Adin EBITDA cna a pl ene ano saan,

  22. Slide 22: Q1 2021 Financial Highlights - Recap

    Q1 2021 Financial Highlights - Recap ‘Total net sales of $14.7 million in Qt 2021 (+2% YoY, -5% versus 4 2020) Demonstrated continued progress building Tru Niagen® into a global brand ‘+ Tru Niagen® net sales of $12.4 milion in Q1 2021 (+12% YoY) *+ Continued sequential growth in Tru Niagen® net sal

  23. Slide 23: Contact Info

    Contact Info Brianna Gerber Vice President of Finance and Investor Relations T: +1.949.419.0288 ext. 127 BriannaG@chromadex.com www.chromadex.com Where to buy TRU NIAGEN® ynmw.truniagen,com www.amazon.com

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