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Zai Lab Presents New Data Demonstrating Zocilurtatug Pelitecan (Zoci) Induces Rapid and Robust Intracranial Responses in Small Cell Lung Cancer with Brain Metastases and Promising Activity in Other Neuroendocrine Carcinomas

SHANGHAI & CAMBRIDGE, Mass., April 17, 2026--Zai Lab Limited (NASDAQ: ZLAB; HKEX: 9688) today announced clinical data indicating zocilurtatug pelitecan (zoci, formerly ZL-1310), a DLL3-targeting antibody-drug conjugate (ADC), provides rapid and robust intracranial responses in patients with previously treated extensive stage small cell lung cancer (ES-SCLC) and brain metastases as measured by independent assessment using modified Response Assessment in Neuro-Oncology for Brain Metastases (mRANO-

articleZai Lab Ltd.April 17, 202610/company/zai-lab-ltd/news/zai-lab-presents-new-data-demonstrating-zocilurtatug-pelitecan-zoci-induces-rapid-and-robust-intracranial-responses-in-small-cell-lung-cancer-with-brain-metastases-and-promising-activity-in-other-neuroendocrine-carcinomas
Zai Lab Presents New Data Demonstrating Zocilurtatug Pelitecan (Zoci) Induces Rapid and Robust Intracranial Responses in Small Cell Lung Cancer with Brain Metastases and Promising Activity in Other Neuroendocrine Carcinomas

About this update from Zai Lab Ltd.

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brain metastasesZai Lab Limitedsmall cell lung cancertreatment optionsZai Labpreclinical dataextensive stageMedical Oncology Departmentclinical datasystemic therapycancer immunotherapysolid tumors