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Xenon to Highlight Phase 3 X-TOLE2 & Long-Term Data for Azetukalner in Focal Onset Seizures at 2026 AAN Annual Meeting
Five abstracts accepted including Late-breaking Science oral and poster presentations of Phase 3 X-TOLE2 study results for azetukalner in focal onset seizures
About this update from Xenon Pharmaceuticals Inc.
[{"type":"text","content":"Five abstracts accepted including Late-breaking Science oral and poster presentations of Phase 3 X-TOLE2 study results for azetukalner in focal onset seizures Poster presentations also include long-term efficacy and safety data from X-TOLE open-label extension study of azetukalner, as well as real-world data regarding the burden of titration and need for no-titration options in epilepsy VANCOUVER, British Columbia and BOSTON, MA, April 07, 2026 (GLOBE NEWSWIRE) -- Xenon Pharmaceuticals Inc. (Nasdaq: XENE), a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development and commercialization of life-changing therapeutics for patients in need, today announced multiple presentations at the upcoming American Academy of Neurology (AAN) Annual Meeting, taking place April 18-22, 2026 in Chicago, Illinois. Five abstracts will be presented, including a Late-breaking Science oral and poster presentation of the topline Phase 3 X-TOLE2 study results for azetukalner in focal onset seizures (FOS), as well as a poster presentation of long-term 48-month azetukalner data from the X-TOLE open label extension study. The Company will also present real-world data highlighting unmet needs in epilepsy, including patient and clinician perspectives on the burden of antiseizure medication (ASM) titration and the impact of comorbidities in epilepsy, as well as data for its preclinical NaV1.1 program in Dravet syndrome. Efficacy & Safety Data for Azetukalner in Focal Onset Seizures Oral & Poster Presentation #7: Results from the Phase 3 X-TOLE2 Study Evaluating Azetukalner, a Novel, Potent KV7 Channel Opener, in Adults with Focal Onset Seizures (FOS)Session: LS1 – Late-breaking Science Session 1Date & Time: Sunday, April 19, 5:36-5:42 pm CT; Poster presentation to follow from 5:54 pm-6:15 pm CT Poster Presentation #10-001: Azetukalner, a Novel, Potent KV7 Channel Opener, in Adults with Focal Epilepsy: ≥48-Month Interim Analysis of the Ongoing 7-Year X-TOLE Open-Label ExtensionSession: P11 – Poster Session 11Date & Time: Wednesday, April 22, 11:45-12:45 pm CT Real-World Epilepsy Data Poster Presentation #11-007: Treatment Experiences with Anti-seizure Medications (ASMs): Patient–Clinician Perspectives on Titration Burden, Quality of Life, and No-Titration OptionsSession: P3 – Poster Session 3Date & Time: Sunday, April 19, ...