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Xenon Pharmaceuticals Reports First Quarter 2023 Financial Results and Provides Corporate Update
XEN1101 Phase 3 epilepsy program continues to make significant progress across all ongoing clinical trials including the recent initiation of X-TOLE3 in
About this update from Xenon Pharmaceuticals Inc.
[{"type":"text","content":"XEN1101 Phase 3 epilepsy program continues to make significant progress across all ongoing clinical trials including the recent initiation of X-TOLE3 in addition to the ongoing X-TOLE2 and X-ACKT Phase 3 clinical trials Anticipate last patient to be screened next month in XEN1101 Phase 2 X-NOVA clinical trial in major depressive disorder with topline data expected in fourth quarter Conference call at 4:30 pm ET today VANCOUVER, British Columbia, May 09, 2023 (GLOBE NEWSWIRE) -- Xenon Pharmaceuticals Inc. (Nasdaq:XENE), a neurology-focused biopharmaceutical company, today reported financial results for the first quarter ended March 31, 2023 and provided a corporate update. Mr. Ian Mortimer, Xenon’s President and Chief Executive Officer, stated, “Our XEN1101 program has continued to build momentum with all planned Phase 3 clinical trials now actively recruiting patients, including X-TOLE2 and X-TOLE3 in patients with focal onset seizures and X-ACKT in patients with primary generalized tonic-clonic seizures. We are excited about the continued progress in our broad Phase 3 program, supported by a robust data package and validated mechanism, including efficacy data from our Phase 2b X-TOLE clinical trial and read-outs from our ongoing open-label extension study. Mr. Mortimer continued, “Based on FDA feedback on our pediatric development plans for XEN1101, we expect to expand the X-ACKT Phase 3 clinical trial to include patients as young as 12 years of age. In addition, XEN1101 pediatric formulation development is ongoing in order to support moving into younger patients with epilepsy. After careful consideration, we are prioritizing our XEN1101 pediatric epilepsy development plans and will no longer pursue the clinical development of XEN496. We wish to extend our sincere gratitude to the patients and their families who participated in the EPIK clinical trial. We intend to work with study investigators to offer an option for continued access through a transition period for those patients currently on XEN496.” Mr. Mortimer added, “We continue to make good progress on our XEN1101 Phase 2 X-NOVA study in major depressive disorder. We expect patient screening to be completed in June with the release of topline data in the fourth quarter. We are also looking forward to a read-out from our Phase 2 partnered program with Neurocrine in the fou...