Business
Xenetic Biosciences, Inc. Bolsters R&D and Regulatory Expertise with Appointment of Reid P. Bissonnette, Ph.D. as Executive Consultant for Translational Research and Development
Dr. Bissonnette brings over 25 years in small molecule and biotherapeutic drug discovery and development, oncology and inflammation research and regulatory
About this update from Xenetic Biosciences, Inc.
[{"type":"text","content":"Dr. Bissonnette brings over 25 years in small molecule and biotherapeutic drug discovery and development, oncology and inflammation research and regulatory expertiseFRAMINGHAM, MA / ACCESSWIRE / May 4, 2023 / Xenetic Biosciences, Inc. (NASDAQ:XBIO) (\"Xenetic\" or the \"Company\"), a biopharmaceutical company focused on advancing innovative immune-oncology technologies addressing hard to treat cancers, today announced it has engaged Reid P. Bissonnette, Ph.D. to serve as an executive consultant for translational research and development and to support the advancement of the Company's DNase-based oncology platform. Xenetic's DNase-based oncology platform is designed to target neutrophil extracellular traps (\"NETs\"), which are weblike structures composed of extracellular chromatin coated with histones and other proteins. NETs are expelled by activated neutrophils, in response to microbial or pro-inflammatory challenges. However, excessive production or reduced clearance of NETs can lead to aggravated inflammatory and autoimmune pathologies, as well as creation and support of pro-tumorigenic niches in the case of cancer growth and metastasis, thereby potentially limiting response to therapy.\"Our confidence in the potential of our DNase-based oncology platform continues to grow and we are pleased with the advancements we have made to date. The depth and breadth of the expertise that Reid brings to our team will prove to be invaluable and is something we can leverage immediately as we look to further define our development and regulatory strategies towards our first FDA IND submission with our DNase-based technology platform,\" commented Jeffrey Eisenberg, Chief Executive Officer of Xenetic.Dr. Bissonnette brings over 25 years of experience in small molecule drug discovery and development and biotherapeutics. He is a well-established translational scientist, drug hunter and senior manager of Oncology and Inflammation drug R&D, particularly with regards to targeted therapeutics, oncology, immuno-oncology, and inflammation therapeutics. He is well experienced in discovery, early and late-stage development, IND-enabling studies and translational sciences, biomarkers and pharmacodynamic markers, from concept to clinic and beyond, identifying and advancing potential therapies from small molecules to biologics including antibodies, ADCs...