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Vor Bio Reports Third Quarter 2022 Financial Results and Provides Company Update

Initial clinical data for VOR33 on track for Q4 2022Eyal C. Attar, M.D. appointed as Chief Medical OfficerInitiated in-house clinical manufacturing at

articleVor Biopharma Inc.November 10, 20223/company/vor-biopharma-inc/news/vor-bio-reports-third-quarter-2022-financial-results-and-provides-company-update
Vor Bio Reports Third Quarter 2022 Financial Results and Provides Company Update

About this update from Vor Biopharma Inc.

[{"type":"text","content":"Initial clinical data for VOR33 on track for Q4 2022Eyal C. Attar, M.D. appointed as Chief Medical OfficerInitiated in-house clinical manufacturing at Cambridge, MA headquarters CAMBRIDGE, Mass., Nov. 10, 2022 (GLOBE NEWSWIRE) -- Vor Bio (Nasdaq: VOR), a clinical-stage cell and genome engineering company, today reported financial results for the three-month period ended September 30, 2022 and provided a business update. “We continue to actively enroll patients in our lead clinical trial, VBP101 and look forward to sharing important initial clinical proof of concept data from this study by year end,” said Dr. Robert Ang, Vor Bio’s President and Chief Executive Officer. “We are excited that our new in-house clinical manufacturing facility is now operational and our IND for VCAR33 is on-track for submission in the first half of 2023. We remain fully focused on our mission to transform the standard of care for patients with blood cancers.” Corporate Highlights Eyal C. Attar, M.D. appointed as Chief Medical Officer. Eyal C. Attar, M.D., has joined Vor Bio as Chief Medical Office. Dr. Attar brings more than 20 years of demonstrated clinical experience including extensive background in hematologic malignancies, with previous roles as a clinician, bench researcher and in clinical development. Initiated in-house clinical manufacturing at Cambridge, MA headquarters. The new facility provides critical operational and strategic control of manufacturing enabling more efficient development of the Company’s novel cell and genome engineering platform and pipeline of engineered hematopoietic stem cell (eHSC) and CAR-T product candidates. The facility will initially manufacture clinical supply to support the IND for VCAR33ALLO with plans to technology transfer the production of VOR33 to the site. Successfully demonstrated potential of base and sequential multiplex editing of HSCs for next-generation acute myeloid leukemia (AML) treatment. Preclinical data presented at the European Society of Gene & Cell Therapy (ESGCT) 29th Congress, October 11-14, demonstrated that multiplex deletion of myeloid antigens CD33 and CLL-1 or CD33 and CD123 in human HSCs resulted in long-term engraftment and persistence of editing. These data showed that Vor Bio’s novel platform enabled efficient removal of multiple target antigens from HSCs while managing off-target...

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