Business
Vor Bio Reports First Quarter 2023 Financial Results and Provides Company Update
VBP101 clinical data update planned at European Hematology Association (EHA) 2023VCAR33ALLO IND submission on-track for 1H 2023 CAMBRIDGE, Mass., May 11, 2023
About this update from Vor Biopharma Inc.
[{"type":"text","content":"VBP101 clinical data update planned at European Hematology Association (EHA) 2023VCAR33ALLO IND submission on-track for 1H 2023 CAMBRIDGE, Mass., May 11, 2023 (GLOBE NEWSWIRE) -- Vor Bio (Nasdaq: VOR), a clinical-stage cell and genome engineering company, today reported financial results for the three-month period ended March 31, 2023, and provided a business update. “We are pleased with the progress we made during the quarter. Our focus continues to be on actively enrolling and treating additional patients in our VBP101 study and submission of the VCAR33ALLO IND, which is on-track for the first half of 2023,” said Dr. Robert Ang, Vor Bio’s President and Chief Executive Officer. “We look forward to sharing additional data from VBP101 at EHA in June, initiating enrollment in VBP301, and treating our first patient with VCAR33ALLO once the IND clears.” Corporate Updates Trem-cel clinical trial (VBP101) continues to actively enroll patients; next data update expected at EHA 2023 The company plans to provide further clinical updates on patients treated in the VBP101 study at the EHA2023 Congress, June 9-11, 2023, in Frankfurt, Germany, presented by Dr. Guenther Koehne, MD, PhD, Deputy Director and Chief of Blood & Marrow Transplant and Hematologic Oncology at Miami Cancer Institute of Baptist Health South Florida.The study continues to see strong investigator enthusiasm with robust enrollment.Additional trem-cel engraftment and hematologic protection data updates are expected by year-end 2023. Trem-cel is a genome-edited allogeneic hematopoietic stem cell transplant (HSCT) that is lacking the CD33 protein. It is designed to replace standard of care transplants for patients suffering from acute myeloid leukemia (AML) and potentially other blood cancers. Trem-cel has the potential to enable powerful targeted therapies in the post-transplant setting including Mylotarg and CD33-targeted CAR-Ts. VCAR33ALLO IND on-track for 1H 2023 submission to U.S. Food & Drug Administration (FDA) VCAR33ALLO is planned to be studied in the VBP301 clinical trial, which will focus on patients who have relapsed following allogeneic stem cell transplant where T cells harvested from the original donor are used as starting material for the drug product.The majority of the planned clinical trial sites for VBP301 overlap with VBP101, which should optimize clinic...