Business
Viridian Therapeutics Reports Fourth Quarter and Full Year 2022 Financial Results and Provides Corporate Updates
- Positive data reported from ongoing Phase 1/2 trial evaluating low-dose VRDN-001 in patients with thyroid eye disease (TED) - - First patient enrolled in
About this update from Viridian Therapeutics, Inc.
[{"type":"text","content":"- Positive data reported from ongoing Phase 1/2 trial evaluating low-dose VRDN-001 in patients with thyroid eye disease (TED) - - First patient enrolled in ‘THRIVE’ Phase 3 trial in patients with active TED, with results expected in mid-2024 - - Initial results from the proof-of-concept study of VRDN-001 in patients with chronic TED are expected in the second quarter of 2023 - - Selection of lead subcutaneous program in TED planned for year-end 2023 - WALTHAM, Mass., March 08, 2023 (GLOBE NEWSWIRE) -- Viridian Therapeutics, Inc. (NASDAQ: VRDN), a biotechnology company focused on discovering and developing potential best-in-class medicines for serious and rare diseases, today announced financial results for the fourth quarter and full year ended December 31, 2022. “2022 was a productive year for Viridian, as we made significant progress and reached multiple important milestones in our TED program with VRDN-001, our lead product candidate. Building on this positive momentum, we are strategically positioned to continue the advancement of our pipeline of TED programs in 2023,” said Scott Myers, President and CEO of Viridian Therapeutics. “As part of my recent appointment as CEO, I look forward to advancing our recently initiated THRIVE Phase 3 trial of VRDN-001 in patients with active TED, generating data in patients with chronic TED, continuing the development of our subcutaneous programs, and beginning to establish our commercial capabilities. These activities support our overall goal to build a fully integrated biopharmaceutical company.” Added Mr. Myers: “We also look forward to providing additional details on one of our preclinical programs later this year. Our preclinical programs have the potential to expand our current pipeline beyond TED and build on our strategy of developing best-in-class medicines that address known limitations of current therapies.” Program highlights Thyroid eye disease (TED) Intravenous (IV) program: VRDN-001Viridian’s lead product candidate, VRDN-001, is a monoclonal antibody believed to act as a full antagonist of insulin-like growth factor-1 receptor (IGF-1R). VRDN-001 is being evaluated in clinical trials for the treatment of active and chronic TED. In January 2023, the Company announced positive data from the third, low-dose cohort in its ongoing Phase 1/2 clinical trial of VRDN-001 in patients w...