New Data Presented at ATS 2023 Reinforce Clinical Utility of Veracyte’s Genomic Tests in Interstitial Lung Disease and Lung Cancer

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[{"type":"text","content":" SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--\nVeracyte, Inc. (Nasdaq: VCYT) today announced new data suggesting its novel genomic tests may positively impact diagnosis and care for patients being evaluated for interstitial lung disease (ILD) or lung cancer. The findings were presented at ATS 2023, the annual meeting of the American Thoracic Society, which is being held May 21-24 in Washington, D.C.\n\n\nFindings from two posters suggest that the Envisia Genomic Classifier helps improve diagnosis and changes treatment decisions for patients with ILD. In an independent, real-world, multi-center study, researchers evaluated data for 98 patients with ILD for whom traditional high-resolution computed tomography (HRCT) and clinical factors alone failed to provide a clear diagnosis of ILD type. The Envisia test identified 42 patients with usual interstitial pneumonia (UIP), a lung-scarring pattern that is a hallmark of idiopathic pulmonary fibrosis (IPF), one of the most serious types of ILD. UIP is also associated with progressive disease that is not IPF. The test also identified 56 patients without UIP.\n\n\nAn Envisia-positive result for UIP prompted an increase in use of anti-fibrotic drugs (from 11.9% to 71.4%), which are used to treat IPF and other progressive ILDs. An Envisia-positive result for UIP also led to a reduction in immuno-suppressant drugs (from 23.8% to 9.5%), which can be harmful to patients with IPF.\n\n\n“IPF and other progressive forms of ILD are often challenging to diagnose using traditional methods. Yet, accurate diagnosis is key to ensuring that patients receive timely and appropriate treatment,” said Fayez Kheir, M.D., a pulmonologist at Massachusetts General Hospital in Boston and an author of the study. “Our findings suggest that use of the Envisia test helped physicians arrive at a more precise diagnosis and begin treatment with appropriate therapy sooner.”\n\n\nFindings from the second Envisia study suggest the genomic test can help identify whether the final diagnosis is IPF or another progressive fibrotic disease. In the study of 135 patients with undiagnosed ILD, researchers found that those with an Envisia-positive result for UIP had a lower baseline lung function, as measured by median forced vital capacity (FVC) testing results, compared to patients with an Envisia-negative result for UIP (64% v...

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