Business
Vera Therapeutics Reports Third Quarter 2021 Financial Results and Provides Corporate Update
Company makes ongoing progress in several areas evaluating atacicept, its lead product candidate Phase 2a JANUS clinical trial showed atacicept administered
About this update from Vera Therapeutics, Inc.
[{"type":"text","content":"Company makes ongoing progress in several areas evaluating atacicept, its lead product candidate Phase 2a JANUS clinical trial showed atacicept administered subcutaneously once weekly demonstrated a durable and substantial reduction in serum galactose-deficient IgA1 (Gd-IgA1) in a dose-dependent manner up to 72 weeks in patients with IgA nephropathy Vera reported approximately $86.2 million in cash and cash equivalents as of September 30, 2021 SOUTH SAN FRANCISCO, Calif., Nov. 10, 2021 (GLOBE NEWSWIRE) -- Vera Therapeutics, Inc. (Nasdaq: VERA), a clinical-stage biotechnology company focused on developing treatments for immunological diseases that improve patients’ lives, today reported its business highlights and financial results for the quarter ending September 30, 2021, and provided a corporate update. “Vera’s third-quarter highlights show continued progress on our business objectives. We remain well-positioned as we continue to advance the clinical program for atacicept, evaluating its potential for patients who suffer from the devastating effects of kidney disease and are lacking effective treatment options,” said Marshall Fordyce, MD, founder and CEO of Vera Therapeutics. “We are pleased by the analysis of our Phase 2a study demonstrating atacicept 75mg reduces Gd-IgA1 to the lowest risk quartile. We continue to make progress enrolling our ongoing Phase 2b ORIGIN study of atacicept in patients with IgA nephropathy – a study powered for proteinuria, and designed to demonstrate atacicept as the first disease-modifying therapy for this indication. We also look forward to the response from the FDA in the fourth quarter of 2021 on our proposed clinical development strategy for atacicept to treat lupus nephritis.” Third Quarter and Recent Business Highlights Phase 2a JANUS clinical trial data presented at American Society of Nephrology’s 2021 Kidney Week showed that atacicept, administered subcutaneously once weekly, demonstrated a substantial reduction in serum galactose-deficient IgA1 (Gd-IgA1) in a dose-dependent manner that was durable through 72 weeks in patients with IgA nephropathy (IgAN). New analysis of these results initially divided JANUS patients into four equal groups according to the quartiles of serum Gd-IgA1 distribution at baseline. Quartile level was then assessed at each timepoint. This additional analysis sho...