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Ultragenyx and Mereo BioPharma to Present Setrusumab Data Update at ASBMR
NOVATO, Calif. and MOUNTAIN VIEW, Calif. and LONDON, Sept. 09, 2022 (GLOBE NEWSWIRE) -- Ultragenyx Pharmaceutical Inc. (NASDAQ: RARE), (“Ultragenyx”), a
About this update from Ultragenyx Pharmaceutical Inc.
[{"type":"text","content":"NOVATO, Calif. and MOUNTAIN VIEW, Calif. and LONDON, Sept. 09, 2022 (GLOBE NEWSWIRE) -- Ultragenyx Pharmaceutical Inc. (NASDAQ: RARE), (“Ultragenyx”), a biopharmaceutical company focused on the development and commercialization of novel products for serious rare and ultra-rare genetic diseases and Mereo BioPharma Group plc (NASDAQ: MREO), (“Mereo”), a clinical-stage biopharmaceutical company focused on rare diseases and oncology, today announced that additional data from Mereo’s Phase 2b ASTEROID study related to setrusumab (UX143) and information on the Phase 2/3 Orbit study will be presented at the American Society for Bone and Mineral Research 2022 Annual Meeting (ASBMR) being held September 9-12, 2022, in Austin, Texas. Setrusumab is a monoclonal antibody in development for the treatment of Osteogenesis Imperfecta (OI), a rare disease affecting approximately 60,000 individuals in the US and Europe. Ultragenyx will present the latest results from the previously presented ASTEROID study and an overview of the design of the ongoing global, seamless Phase 2/3 Orbit study at the meeting. Data will also be presented from the IMPACT Survey, the largest collection of data in OI and a joint research project between the Osteogenesis Imperfecta Foundation (OIF), and the umbrella organization Osteogenesis Imperfecta Federation Europe (OIFE) and their members, supported by Mereo BioPharma. Details of the ASBMR data presentations are as follows: Abstract Title: Orbit: A Randomized, Double-Blind, Placebo-controlled, Phase 2/3 Study to Assess the Efficacy and Safety of Setrusumab in Pediatric and Young Adult Participants with Osteogenesis Imperfecta (Ominsky M et al.)Presentation: PosterSession Date and Time: Saturday, September 10, 2022, 13:00-15:00 Central TimePresentation Number: LB SAT-897 Abstract Title: The IMPACT survey provides unique insights into the experiences of adults with osteogenesis imperfecta (OI) through self-reported data (Rauch F et al.)Presentation: PosterSession Date and Time: Sunday, September 11, 2022, from 13:00-15:00 Central TimePresentation Number: SUN-667 Abstract Title Changes in BMD and Bone Turnover Markers Following Discontinuation of Setrusumab After 1 Year of Treatment in Adults with Osteogenesis Imperfecta (Javaid K et al.) Presentation: Oral PresentationSession Date and Time: Monday, September 12, 2022, ...