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Twist Bioscience Announces Availability of Synthetic SARS-CoV-2 RNA Controls

-- Positive Controls can be Used as Reference to Verify and Validate RT-PCR and NGS Assays -- SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)-- Twist Bioscience

articleTwist Bioscience CorporationMarch 12, 20203/company/twist-bioscience-corp/news/twist-bioscience-announces-availability-of-synthetic-sars-cov-2-rna-controls
Twist Bioscience Announces Availability of Synthetic SARS-CoV-2 RNA Controls

About this update from Twist Bioscience Corporation

[{"type":"text","content":"\n-- Positive Controls can be Used as Reference to Verify and Validate RT-PCR and NGS Assays -- \n\n SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--\nTwist Bioscience Corporation (Nasdaq: TWST) today announced the availability of two synthetic SARS-CoV-2 RNA Controls. Positive controls provide quality control measures for the development, verification, and validation for diagnostic tests including both next-generation sequencing (NGS) and reverse transcription-polymerase chain reaction (RT-PCR) assays; determination of the limit of detection; and monitoring of day-to-day test variations.\n\n\n“The recent coronavirus outbreak has led to a rapid response from the viral research and therapeutics community around the world, however in the face of a pandemic, time is not on our side and better tools are needed,” said Emily M. Leproust, Ph.D., CEO and co-founder of Twist Bioscience. “These research teams need robust and reliable genomics products to classify and characterize viral samples, as well as genome engineering tools to build vaccines to help stop the spread of this deadly virus. We are employing our capabilities to write DNA at scale to support these important efforts.”\n\n\nTwist is offering two fully-synthetic SARS-CoV-2 RNA controls, available for distinct reference sequences:\n\n\n\nTwist Synthetic SARS-CoV-2 RNA Control 1 (MT007544.1)\n\n\nTwist Synthetic SARS-CoV-2 RNA Control 2 (MN908947.3)\n\n\n\nThe Twist synthetic controls are designed based on two specific SARS-CoV-2 variants, cover the full viral genome and are sequence-verified. In addition, Twist is able to create synthetic RNA controls from other strains or sequences of the virus, and can provide these custom controls within two weeks. For more information on the Twist Synthetic SARS-CoV-2 RNA controls, please visit: https://www.twistbioscience.com/coronavirus-research-tools. Customers purchasing synthetic controls are subject to Twist’s leading biosecurity screening protocols and applicable laws and regulations.\n\n\nIn addition to working with customers to provide synthetic controls, Twist is delivering key products for academic institutions and healthcare companies fighting the global health crisis. The company is synthesizing Clonal Genes and Gene Fragments that enable quick development of subunit vaccines from one or more antigen-presenting viral gene or pe...

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