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Tonix Pharmaceuticals Announces Issuance of U.S. Patent Covering Potentiated Intranasal Oxytocin (TNX-1900) for the Treatment of Pain
New patent expected to expire in 2036 Phase 2 Study for Prevention of Migraine Headache Expected to Start Second Half 2022 CHATHAM, N.J., Aug. 01, 2022 (GLOBE
About this update from Tonix Pharmaceuticals Holding Corp.
[{"type":"text","content":"New patent expected to expire in 2036 Phase 2 Study for Prevention of Migraine Headache Expected to Start Second Half 2022 CHATHAM, N.J., Aug. 01, 2022 (GLOBE NEWSWIRE) -- Tonix Pharmaceuticals Holding Corp. (Nasdaq: TNXP), a clinical-stage biopharmaceutical company, announced today that the United States Patent and Trademark Office (USPTO) issued U.S. Patent 11,389,473 to the Company on July 19, 2022. The patent, entitled \"Magnesium-Containing Oxytocin Formulations and Methods of Use\" claims methods and compositions for treating pain, including that incident to migraine headaches, using intranasal magnesium-containing oxytocin formulations. This patent, excluding possible patent term extensions, is expected to provide Tonix with U.S. market exclusivity until January 2036. In late 2021, Tonix received Investigational New Drug (IND) clearance from the U.S. Food and Drug Administration (FDA) to support the initiation of a Phase 2 study of TNX-1900 (intranasal potentiated oxytocin) for the prevention of migraine headache in chronic migraineurs. The Company continues to expect to begin enrollment in the Phase 2 study during the second half of 2022. “The USPTO’s issuance of this patent is an important milestone in protecting our expanding central nervous system therapeutic portfolio,” said Seth Lederman, M.D., Chief Executive Officer of Tonix Pharmaceuticals. “An estimated four million individuals in the United States suffer from chronic migraine. We believe that by engaging and stimulating oxytocin receptors in the trigeminal ganglia, TNX-1900 has the potential to help those chronic migraine sufferers. TNX-1900 contains magnesium, which Tonix has shown potentiates the action of oxytocin at oxytocin receptors in animal models.” About Migraine Migraine is a neurological condition that manifests in throbbing headache, often on one side of the head, that lasts at least four hours. It can also be accompanied by nausea, vomiting, visual disturbances, and sensitivity to bright light, strong smells, and loud noises1. Epidemiological studies indicate that globally, approximately 1.2 billion individuals suffer from migraines annually.2 In the U.S., approximately 39 million Americans suffer from migraines and among these individuals, approximately four million experience chronic migraines (15 or more headache days per month).2 About TNX-1900...