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Tarsus Presents New Findings from Two Studies Demonstrating the Impact of Demodex Blepharitis at the ARVO 2022 Annual Meeting
IRVINE, Calif., May 05, 2022 (GLOBE NEWSWIRE) -- Tarsus Pharmaceuticals, Inc. (NASDAQ: TARS), whose mission is to focus on unmet needs and apply proven
About this update from Tarsus Pharmaceuticals, Inc.
[{"type":"text","content":"IRVINE, Calif., May 05, 2022 (GLOBE NEWSWIRE) -- Tarsus Pharmaceuticals, Inc. (NASDAQ: TARS), whose mission is to focus on unmet needs and apply proven science and new technology to revolutionize treatment for patients, starting with eye care, presented data from its Atlas Continuation study on the negative impact Demodex blepharitis has on daily life and visual function among certain patient groups, as well as preliminary findings from the Pandora study on coexisting bacterial burden for patients with Demodex blepharitis. Both studies were presented at the Association for Research in Vision and Ophthalmology (ARVO) 2022 Annual Meeting. Accepted abstracts include: The Impact of Demodex Blepharitis on Patients and Healthcare System: Results from the Atlas Continuation Study; Blake Simmons, O.D., et al.Demodex Blepharitis and Coexisting Bacterial Burden in Eye Care Patients: The Pandora Study; Kiersten Snyder, M.D., et al. “This research reinforces the significant burden and clinical impact of Demodex blepharitis, particularly among the most commonly seen patients in eye care practices,” said Bobak Azamian, M.D., Ph.D., President and Chief Executive Officer of Tarsus. “We also recently announced strong, positive topline results from our second pivotal trial, Saturn-2, studying our lead investigational therapeutic, TP-03, for the treatment of Demodex blepharitis. With this positive data, we plan to submit a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) later this year, which is exciting for eye care professionals and the millions of patients suffering from this disease without an effective treatment option. We are committed to advancing our path forward to bring a potential definitive standard of care to these patients in need.” About TP-03TP-03 (lotilaner ophthalmic solution, 0.25%) is a novel, investigational therapeutic designed to resolve the signs of Demodex blepharitis by targeting and eradicating the root cause of the disease – Demodex mite infestation. Lotilaner is a well-characterized anti-parasitic agent that paralyzes and eradicates Demodex mites by selectively inhibiting the GABA-Cl channels. It is a highly lipophilic molecule, which may promote its uptake in the oily sebum of the eyelash follicle where the mites reside. TP-03 was evaluated in two pivotal trials collectively involving 833 pat...