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Standard BioTools Achieves New Record of the Most Protein Measurements on the Most Sample Types with Expansion of the SomaScan® 11K Platform
Cerebrospinal fluid, cell lysates and tissue homogenates open new avenues for biomarker discovery in oncology and neurology SOUTH SAN FRANCISCO, Calif., Sept.
About this update from Standard Biotools Inc.
[{"type":"text","content":"Cerebrospinal fluid, cell lysates and tissue homogenates open new avenues for biomarker discovery in oncology and neurology\nSOUTH SAN FRANCISCO, Calif., Sept. 24, 2024 (GLOBE NEWSWIRE) -- Standard BioTools Inc. (Nasdaq:LAB), today announced that the SomaScan® 11K Platform now includes protein measurements on a broader range of sample types, including cerebrospinal fluid (CSF), aqueous humor, tissue homogenates and cell lysates. The SomaScan® Platform provides the largest number of protein measurements and the greatest number of orthogonally confirmed protein reagents in the proteomics industry —11,000 protein measurements simultaneously from sample volumes as low as 55 µl—giving researchers access to half of the human proteome in just one assay. “These new sample types expand the SomaScan11K Platform’s ability to provide important biological insights, supporting translational medicine by advancing research findings into disease causation, clinical pharmacology and drug development,” said Standard BioTools Chief Medical Officer Stephen A. Williams, MD, PhD. “The use of high-throughput proteomics in cerebrospinal fluid for neurodegenerative disease research, for example, is key to providing information on biological changes occurring in the brain. The SomaScan Platform’s sensitivity to these changes is expected to give researchers a wealth of mechanistic neurological data.” The SomaScan Platform is the only proteomic approach on the market that scales. The precision of the SomaScan Assay has been maintained or improved across all versions, up to and including the most recent release covering 11,000 protein measurements—a challenge that antibody-based assays have failed to overcome. The platform offers low coefficients of variation (CV), a median around 5%, which means the SomaScan Assay can provide more statistical power to make discoveries. Precision and reproducibility are of paramount importance in clinical trials using precious sample types where pharma customers are using proteomics on this scarce biomaterial for smaller or shorter trials. The SomaScan Platform can supply more data, more precisely, with fewer and smaller volumes of samples such as CSF, cell lysates and tissue homogenates. “This extension of the SomaScan 11K Assay is part of a continuous improvement effort that will expand the number of reliably measured prot...