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Solid Biosciences Outlines Key Priorities for Advancing Diversified Neuromuscular and Cardiac Development Pipeline and Establishing Leadership in Precision Genetic Medicines
- Duchenne: Dosed four patients in INSPIRE DUCHENNE clinical trial; SGT-003 has been well tolerated in all patients with no SAEs observed; initial three
About this update from Solid Biosciences Inc.
[{"type":"text","content":"- Duchenne: Dosed four patients in INSPIRE DUCHENNE clinical trial; SGT-003 has been well tolerated in all patients with no SAEs observed; initial three patient data expected Q1 2025 - - FA: First-in-human clinical study of SGT-212 utilizing a dual route of administration to treat Friedreich’s ataxia (FA) anticipated in 2H 2025 following recent FDA IND clearance - - CPVT: Submission of IND for SGT-501 on track for 1H 2025; the submission will expand clinical-stage portfolio to three unique candidates in diverse indications with significant unmet need - - Cash: Company enters 2025 with approximately $148.9 million in cash and investments1 as of 12/31/2024; expected to fund key strategic priorities into 2026 - CHARLESTOWN, Mass., Jan. 15, 2025 (GLOBE NEWSWIRE) -- Solid Biosciences Inc. (Nasdaq: SLDB) (the “Company” or “Solid”), a life sciences company developing precision genetic medicines for neuromuscular and cardiac diseases, will provide a corporate update outlining the Company’s expanded clinical-stage pipeline and 2025 objectives as it completes its transformation into a multi-program leader in the development of precision genetic medicines. Bo Cumbo, President and CEO, and Gabriel Brooks, M.D., Chief Medical Officer, will provide the update at the 43rd Annual J.P. Morgan Healthcare Conference on Wednesday, January 15, 2025, at 3:45 p.m. PT (6:45 p.m. ET). “At the time I joined Solid Biosciences there was a singular focus on genetic treatments for Duchenne muscular dystrophy,” said Bo Cumbo, President and CEO of Solid Biosciences. “In the last two years, we have broadened the pipeline to include gene therapy treatments for other devastating genetic neuromuscular and cardiac diseases, entered the clinic with our next generation gene therapy for Duchenne, opened a second IND with an industry first dual route of administration gene therapy to treat Friedreich’s ataxia, and continued to make advancements in next-generation capsid technologies, novel promoters, immunomodulation techniques, and manufacturing excellence. We are committed to innovating and building a true ‘next generation’ genetic medicines company, while maintaining Solid’s historic focus on the needs of the patient.” He continued: “With two clinical stage assets and a third IND submission anticipated in 1H 2025, Solid Biosciences stands on the threshold of realizi...