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Sera Prognostics Presents Data Demonstrating Prediction of Preeclampsia Utilizing Protein Biomarker and Clinical Factors at SRI Annual Meeting
SALT LAKE CITY, March 18, 2022 /PRNewswire/ -- Sera Prognostics Inc., The Pregnancy Company® (Nasdaq: SERA), focused on improving maternal and neonatal health
About this update from Sera Prognostics, Inc.
[{"type":"text","content":"SALT LAKE CITY, March 18, 2022 /PRNewswire/ -- Sera Prognostics Inc., The Pregnancy Company® (Nasdaq: SERA), focused on improving maternal and neonatal health by providing innovative pregnancy biomarker information to doctors and patients, today presented data demonstrating the effective prediction of preeclampsia using protein biomarkers and clinical factors. The presentation titled \"Comparison of Protein Biomarkers to Clinical Factors for Preeclampsia in Two Cohorts\" was given by lead author Julja Burchard et al this morning at the 69th Annual Meeting of the Society for Reproductive Investigation (SRI) in Denver, Colorado, during Late Breaking Session LB-002 from 9:00-10:30 AM.\n\n \n \n \n \n \n \n\n \nThis study was a secondary analysis of two large independent pregnancy cohorts totaling more than 10,500 enrolled patients, PAPR (NCT01371019; 11 U.S. sites, 2011-2013) and TREETOP (NCT02787213; 18 U.S. sites, 2016-2018) investigating the ability of 6 clinical factors and 31 protein biomarkers to predict either preeclampsia at any gestational age or preterm preeclampsia occurring before 37 weeks of pregnancy in women prior to receiving a clinical diagnosis of preeclampsia. Of the 6 clinical factors, only having had preeclampsia in a prior pregnancy was significantly predictive of both outcomes in both studies. Of 31 biomarkers, significant prediction of preeclampsia and preterm preeclampsia was shown by 7 and 5 biomarkers, respectively, in both studies. Biomarkers, paired with the clinical predictor preeclampsia in a previous pregnancy, showed additive predictive performance and contributed more strongly for prediction of preterm preeclampsia. Biomarkers alone, whether or not clinical factors are available, also showed independent predictive performance of preeclampsia, enabling more timely interventions designed to address a patient's individual risk.\n\"We are pleased to have this important study completed on preeclampsia, a major cause of prematurity and neonatal and maternal health complications,\" said Gregory C. Critchfield, MD, MS, Chairman and Chief Executive Officer of Sera Prognostics. \"This study, conducted by leading researchers in maternal-fetal medicine, demonstrates progress on our pipeline and our ongoing commitment to providing valuable information to doctors and pregnant women in Sera Prognostics' journey a...