Business
SELLAS Life Sciences Provides Business Update and Reports First Quarter 2023 Financial Results
Phase 1 Study of Novel, Highly Selective CDK9 Inhibitor GFH009 Successfully Completed for Patients with Acute Myeloid Leukemia; 94% of Patients Enrolled to
About this update from Sellas Life Sciences Group, Inc.
[{"type":"text","content":"Phase 1 Study of Novel, Highly Selective CDK9 Inhibitor GFH009 Successfully Completed for Patients with Acute Myeloid Leukemia; 94% of Patients Enrolled to Date Alive and Durable Remission in Patient with Acute Myeloid Leukemia > 6 months Phase 3 REGAL Study of Galinpepimut-S in Patients with Acute Myeloid Leukemia on Track for Interim Analysis by Late 2023/Early 2024 NEW YORK, May 11, 2023 (GLOBE NEWSWIRE) -- SELLAS Life Sciences Group, Inc. (NASDAQ: SLS) (“SELLAS’’ or the “Company”), a late-stage clinical biopharmaceutical company focused on the development of novel therapies for a broad range of cancer indications, today provided a business update and reported its financial results for the quarter ended March 31, 2023. “We are pleased with the continued advancement of both our galinpepimut-S (GPS) and GFH009 clinical programs during the first quarter of 2023, which positions us for near-term execution of several key value-driving milestones,” said Angelos Stergiou, MD, ScD h.c., President and Chief Executive Officer of SELLAS. “Positive topline data for the patient group with acute myeloid leukemia (AML) from the GFH009 Phase 1 dose-escalation trial in relapsed/refractory myeloid malignancies suggests strong evidence of anti-tumor activity and survival benefit in this group with no significant safety issues. This supports advancement to a Phase 2a trial in patients with AML in combination with azacitidine and venetoclax, which we are initiating this quarter, with topline data expected in Q4 2023. Last month, the Independent Data Monitoring Committee (IDMC) also recommended that our GPS Phase 3 REGAL study continue without any modifications and is expected to meet again in Q3 to provide further guidance.” Dr. Stergiou continued “The key objectives for us this quarter and next, among others, will include: the initiation of the GFH009 Phase 2a study in AML patients in combination with azacitadine and venetoclax;completion of, and report of, data from the lymphoma patient group from the GFH009 Phase 1 study;report of topline data from the GPS investigator-sponsored trial (IST) in malignant pleural mesothelioma (MPM);abstract acceptance of our GPS ovarian cancer data from a major medical gynecological conference;3D Medicines participation in the REGAL study; andmeeting of, and feedback from, the IDMC for the REGAL study.” “It was ...