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SCYNEXIS Presents Interim Analysis from FURI at Virtual IDWeek 2021 Showing Favorable Therapeutic Response in Severe Hospital-Based Fungal Infections Treated with Oral Ibrexafungerp
Subpopulation analysis of 74 patients from ongoing Phase 3 FURI study demonstrated similar efficacy against multiple serious fungal infections JERSEY CITY,
About this update from Scynexis, Inc.
[{"type":"text","content":"Subpopulation analysis of 74 patients from ongoing Phase 3 FURI study demonstrated similar efficacy against multiple serious fungal infections\nJERSEY CITY, N.J., Sept. 29, 2021 (GLOBE NEWSWIRE) -- SCYNEXIS, Inc. (NASDAQ: SCYX), a biotechnology company pioneering innovative medicines to overcome and prevent difficult-to-treat and drug-resistant infections, today announced an oral presentation of analyses of interim data from its ongoing Phase 3 FURI study showing favorable clinical activity of oral ibrexafungerp in severe hospital-based fungal infections across multiple serious fungal infections. The compilation and disease subset analyses are being presented during IDWeek, taking place virtually September 29 – October 3, 2021. “We are very pleased to share the results of these analyses to help provide greater understanding of ibrexafungerp and its potential to help patients suffering from a multitude of severe fungal infections, many of which have high mortality rates,” said Marco Taglietti, M.D., President and Chief Executive Officer of SCYNEXIS. “Based on the accumulation of data to date and additional analysis of therapeutic response by disease area, results demonstrate that ibrexafungerp has similar efficacy across a broad spectrum of serious fungal diseases and in the future could be valuable in the treatment of patients who have failed or are intolerant to currently available therapies.” Oral presentation details: Oral Ibrexafungerp Outcomes by Fungal Disease in Patients from an Interim Analysis of a Phase 3 Open-label Study (FURI) – Peter G. Pappas, M.D., University of Alabama at Birmingham (UAB)Oral Presentation – New Findings in Medical Mycology: O-25.Summary: Data from an interim analysis of the combined data of 74 patients from the Phase 3 FURI clinical study evaluating oral ibrexafungerp for the treatment of patients with refractory candidiasis, patients who were intolerant to the standard of care, or patients who were unable to receive an approved oral antifungal option (e.g., susceptibility of the organism) and a continued IV antifungal therapy was clinically undesirable or unfeasible, found that oral ibrexafungerp provided an overall favorable therapeutic response in patients with 13 distinct types of fungal infections. Of the 74 patients treated with oral ibrexafungerp 62.1% showed complete or partial response, ...