Business
SCYNEXIS Announces Positive Interim Data from Phase 3 FURI and CARES Studies Highlighting Oral Ibrexafungerp's Potency Against Severe Fungal Infections
Data reinforce findings from previous analyses demonstrating oral ibrexafungerp’s potential to combat difficult-to-treat and refractory fungal infections in
About this update from Scynexis, Inc.
[{"type":"text","content":"Data reinforce findings from previous analyses demonstrating oral ibrexafungerp’s potential to combat difficult-to-treat and refractory fungal infections in the hospital setting.Ongoing FURI and CARES studies are a key component of the SCYNEXIS strategy to build ibrexafungerp into a broad antifungal franchise.SCYNEXIS is presenting the fourth interim analysis from FURI and the second interim analysis from CARES during the 32nd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) being held in Lisbon, Portugal, April 23-26, 2022. JERSEY CITY, N.J., April 22, 2022 (GLOBE NEWSWIRE) -- SCYNEXIS, Inc. (NASDAQ: SCYX), a biotechnology company pioneering innovative medicines to overcome and prevent difficult-to-treat and drug-resistant infections, today announced positive interim data from its ongoing Phase 3 FURI and CARES studies. “These results further support ibrexafungerp’s potential to treat complex fungal infections in the hospital setting,” said David Angulo, M.D., Chief Medical Officer of SCYNEXIS. “There is a significant need for a new antifungal therapy, particularly one that is active against Candida species frequently resistant to other antifungal agents, such as Candida auris and Candida glabrata. The data from more than 130 combined patients treated in our FURI and CARES studies further confirm that oral ibrexafungerp has a potential to play a significant role in treating patients with very challenging fungal diseases.” The ongoing Phase 3 open-label, single-arm FURI study is evaluating oral ibrexafungerp for the treatment of patients with severe fungal infections who are either intolerant to standard antifungal therapy or experience refractory fungal infections despite treatment. The CARES study, also an ongoing Phase 3 open-label, single-arm trial, is evaluating oral ibrexafungerp in patients with systemic infections caused by C. auris, an organism that is often multi-drug resistant, associated with high mortality and classified by the U.S. Centers for Disease Control and Prevention (CDC) as an “Urgent Threat” to public health.1 The data summarized below includes the results of study patients who had completed their treatment as of October 2021 and have been reviewed by a Data Review Committee (DRC), including 47 cases from the most recent review. FURICARESAggregate (FURI+CARES)Global ResponseN=11...