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SCYNEXIS Announces $3 Million National Institutes of Health Grant Has Been Awarded to Case Western Reserve University Researchers to Study Second Generation Fungerp (SCY-247) to Fight Drug-Resistant Fungi
Researchers to study the potential of SCY-247 to fight Candida auris (C.auris), a multidrug-resistant pathogen named as an “urgent threat” by the Centers for
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[{"type":"text","content":"Researchers to study the potential of SCY-247 to fight Candida auris (C.auris), a multidrug-resistant pathogen named as an “urgent threat” by the Centers for Disease Control (CDC) and included in the “critital priority group” on the World Health Organization (WHO) fungal priority pathogens list (FPPL). SCY-247 is a broad-spectrum, oral and IV antifungal under development by SCYNEXIS as a potential systemic therapeutic option for multiple drug-resistant pathogens. JERSEY CITY, N.J., Nov. 30, 2022 (GLOBE NEWSWIRE) -- SCYNEXIS, Inc. (NASDAQ: SCYX), a biotechnology company pioneering innovative medicines to overcome and prevent difficult-to-treat and drug-resistant infections, today announced that researchers from Case Western Reserve University in Cleveland have been awarded a competitive research grant of more than $3 million by the National Institutes of Health (NIH), to investigate a second generation fungerp (SCY-247) developed by SCYNEXIS as a potential treatment for Candida auris (C.auris), a multidrug-resistant yeast that causes serious and often deadly infections. The five-year grant from the National Institute of Allergy and Infectious Diseases of NIH will allow the team led by researchers at the Case Western Reserve School of Medicine and University Hospitals Cleveland Medical Center to evaluate this novel antifungal drug developed by SCYNEXIS. The research team will be led by Mahmoud Ghannoum, Ph.D., professor of dermatology and pathology at the School of Medicine and director of the Center for Medical Mycology at University Hospitals Medical Center, Case Western Reserve University, as principal investigator, and Thomas McCormick, Ph.D., an associate professor at the School of Medicine. “It is thrilling to see the NIH fund this important research to investigate oral and IV SCY-247, one of our patented triterpenoid antifungals, to target drug resistant C. auris, where there is great need due to limited treatment options and the potential to save lives,” said Marco Taglietti, M.D., President and Chief Executive Officer of SCYNEXIS. “We congratulate Dr. Ghannoum on receiving this grant and want to express our gratitude for his ongoing commitment to patients suffering from terrible and deadly fungal infections.” C. auris has emerged in recent years as a global threat causing serious invasive infections with mortality as high...