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Sangamo Therapeutics Announces Presentations At 2019 Annual Meeting Of The American Society Of Gene & Cell Therapy
BRISBANE, Calif., April 15, 2019 /PRNewswire/ -- Sangamo Therapeutics, Inc. (NASDAQ: SGMO), a genomic medicine company, today announced that Sangamo
About this update from Sangamo Therapeutics, Inc.
[{"type":"text","content":"BRISBANE, Calif., April 15, 2019 /PRNewswire/ -- Sangamo Therapeutics, Inc. (NASDAQ: SGMO), a genomic medicine company, today announced that Sangamo scientists and collaborators will present data from the Company's clinical and preclinical pipeline at the 22nd Annual Meeting of the American Society of Gene & Cell Therapy (ASGCT) being held April 29th to May 2nd, 2019 in Washington, D.C. \n\n \nAbstracts accepted for presentation highlight data from the Company's gene therapy program in Fabry disease; ex vivo gene-edited cell therapy programs in hemoglobinopathies being developed in partnership with Sanofi; and preclinical programs for CNS diseases using Sangamo's gene regulation approach, which include tauopathies, C9ORF72-linked ALS in collaboration with Pfizer, and Huntington's disease in collaboration with Takeda.\n\"Sangamo's strong scientific presence at ASGCT demonstrates the breadth of our therapeutic pipeline and our expertise in innovative genomic medicines research and development,\" said Adrian Woolfson, M.D., Ph.D., Sangamo's Executive Vice President of Research and Development. \"Through our pioneering work in developing zinc fingers for ex vivo and in vivo genome editing, we've gained invaluable insights into AAV manufacturing and delivery, as well as gene editing precision, efficiency, and specificity. We're now applying these insights to our integrated portfolio of programs in both gene therapy and ex vivo cell therapy as well as to our new zinc finger protein transcription factor gene regulation platform, which will be showcased at this year's meeting.\"\nASGCT Annual Meeting presentations \nGene Therapy\nLiver-Targeted AAV Gene Therapy Vectors Produced at Clinical Scale Result in High, Continuous Therapeutic Levels of α-GalA Enzyme Activity and Effective Substrate Reduction in a Mouse Model of Fabry Disease – Abstract #794 Session: Metabolic, Storage, Endocrine, Liver and Gastrointestinal Diseases II Poster Presentation – Wednesday, May 1; 5:00PM ETEx Vivo Gene-Edited Cell Therapy\nZinc Finger Nuclease-Mediated Disruption of the BCL11A Erythroid Enhancer in Human Hematopoietic Stem and Progenitor Cells Results in Enriched Bialleleic Editing with Highly Replicable and Precise On-Target Small Indels and Allele-Additive Increases in Fetal Hemoglobin – Abstract #972 Session: Gene Editing for Red Blood Cell Diso...