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Significant Milestones achieved by RUA Vascular
Significant Milestones achieved by RUA Vascular.
About this update from Rua Life Sciences Plc
[{"type":"text","content":"\n \n \n RNS Number : 1448V\n RUA Life Sciences PLC\n 05 August 2020\n \n \n \n \n \n \n \n \n \n \n RUA Life Sciences Plc\n \n \n (\"RUA Life Sciences\", the \"Company\" or the \"Group\")\n \n \n Significant Milestones achieved by RUA Vascular \n \n \n RUA Life Sciences, the holding company of a group of medical device businesses focused on the exploitation of the world's leading long-term implantable biostable polymer (Elast-EonTM), is pleased to announce that its subsidiary, RUA Vascular, the business which is developing Elast-EonTM sealed vascular grafts and cardiac/vascular patches, has recently achieved significant milestones for each of these products on the path to early commercialisation.\n \n \n Large Bore Vascular Grafts at \"Design Freeze\"\n \n \n The three key design inputs for the RUA Vascular large bore (18mm to 38mm) vascular graft project were: \n \n \n 1. The elimination of animal by-products; \n \n \n 2. Improving on the permeability and porosity claims of currently available market leading products; and\n \n \n 3. Improving handling characteristics and surgical feel. \n \n \n During the development of the Elast-Eon™ sealed large bore vascular graft, a number of different iterations were produced, each adding to the know-how and intellectual property relating to the thin film polymer sealing of a vascular graft without the need for any animal tissue. \n \n \n Subsequently, a combination of animal pilot studies and bench testing have demonstrated that the thin film polymer sealed vascular graft is indistinguishable in handling and needle/suture acceptance from the currently available commercial collagen and gelatin sealed grafts. The latest animal pilot study demonstrated that \n on release of clamp, allowing blood to flood into the graft at normal blood pressure, no leaks were recorded \n and bench testing to the ISO7198:2017 standard measured the water permeability to be significantly below the market leading animal by-product coated grafts. In addition to achieving the three key design objectives set out above, all other design inputs have been met to the satisfaction of the technical team and a commercially viable and validatable product has been developed. \n \n \n The large bore graft project is now at \"design freeze\" stage and the technical team is confident t...