Health
[Ad hoc announcement pursuant to Art. 53 LR] Roche announces positive Phase II results for its dual GLP-1/GIP receptor agonist CT-388 in people living with obesity
A once-weekly subcutaneous injection of CT-388 achieved a statistically significant placebo-adjusted weight loss of 22.5% (p < 0.001) at 48 weeks at the highest dose tested (24 mg), without reaching a weight loss plateau 54% of participants on the 24 mg dose achieved resolution of obesity (BMI <30 kg/m2) vs. 13% in the placebo groupCT-388 demonstrated a safety and tolerability profile generally consistent with its drug class with no new or unexpected safety signals Basel, 27 January 2026 - Roche
![[Ad hoc announcement pursuant to Art. 53 LR] Roche announces positive Phase II results for its dual GLP-1/GIP receptor agonist CT-388 in people living with obesity](https://media.zenfs.com/en/globenewswire.com/d295bae68c32358ba6ac888e76c1cca2)
About this update from Roche Holding Ltd
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