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Rhythm Pharmaceuticals Presents First-ever Data Showing Improvements in Health-related Quality of Life for Patients Living with Bardet-Biedl Syndrome at ObesityWeek® 2021
-- Additional oral presentation details safety and efficacy data from Phase 3 trial of setmelanotide in BBS ---- Also presenting new hunger data from SRC1 and
About this update from Rhythm Pharmaceuticals, Inc.
[{"type":"text","content":"-- Additional oral presentation details safety and efficacy data from Phase 3 trial of setmelanotide in BBS ---- Also presenting new hunger data from SRC1 and SH2B1 cohorts in Phase 2 Basket Trial and new data on utilization of URO® genetic testing program – BOSTON, Nov. 01, 2021 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a commercial-stage biopharmaceutical company committed to transforming the care of people living with rare genetic diseases of obesity, this week presented the first-ever data on the health-related quality of life (HRQOL) and experience of patients with Bardet-Biedl syndrome (BBS) who were treated in its Phase 3 trial of setmelanotide at The Obesity Society’s ObesityWeek®, a virtual conference that runs from Nov. 1 to 5. Also at ObesityWeek®, the company shared an oral presentation detailing efficacy and safety data from its Phase 3 trial of setmelanotide in BBS and Alström syndrome, as well as poster presentations with new hunger reduction data from the SRC1 and SH2B1 genetic deficiency cohorts in its exploratory Phase 2 Basket Trial. Additional presentations include new data on utilization of the Uncovering Rare Obesity® (URO) genetic testing program, an analysis of the frequency of melanocortin-4 receptor (MC4R) pathway variants in U.S. patients with severe obesity, and a review of single minded-1 (SIM1) missense variants associated with severe obesity. “We are excited to share multiple presentations at ObesityWeek, which demonstrate continued progress toward our goal of transforming the care of people living with rare genetic diseases of obesity,” said Linda Shapiro, M.D., Ph.D., Chief Medical Officer of Rhythm. “The new BBS HRQOL data build on the safety and efficacy results we first announced last year, further validating our belief in setmelanotide’s potential as the first-ever therapy to address the hyperphagia and severe obesity that affect the lives of patients and families living with BBS. In addition, the new data from the cohorts of patients with SH2B1 and SRC1 genetic deficiencies in our Phase 2 Basket Trial demonstrated setmelanotide’s ability to reduce hunger in people living with these rare genetic diseases of obesity in the trial, further reinforcing our confidence in the DAYBREAK and EMANATE trials we are launching soon to expand our clinical evaluation into a total of 3...