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Resverlogix Scientific Data Presented at EAS Congress
Resverlogix Scientific Data Presented at EAS Congress
About this update from Resverlogix Corp.
[{"type":"text","content":"\n\n\n\n Jun. 22, 2010 (Canada NewsWire Group) -- New data from Phase 1b/2a trial included\n\nTSX Exchange Symbol: RVX\n\n Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) announced today that key scientific data was communicated in an oral presentation highlighting the novel features of the Company's lead drug RVX-208 at the European Atherosclerosis Society Congress (EAS) conference being held in Hamburg, Germany. The presentation titled "RVX-208 given orally raises plasma ApoA-I and HDL in human clinical trials," was presented by Dr. Norman Wong, MD, Chief Scientific Officer of Resverlogix.\n"The data presented in Germany today further highlights that patients with low HDL/Apo-Al benefit most. For those patients in the highest risk category, subjects with low baseline HDL/Apo-Al, our data demonstrated that RVX-208 increased plasma levels of Apo-Al in the order of 13.25% compared to placebo. This data, combined with similar low baseline HDL/Apo A-l data analysis of the upcoming ASSERT trial data will further support the design of a very effective and efficient ASSURE trial," said Donald J. McCaffrey, President & CEO of Resverlogix.\nResverlogix recently completed a Phase 2 clinical trial called ASSERT to study RVX-208 an oral small molecule therapy for the treatment of atherosclerosis. The ASSERT trial enrolled subjects with stable coronary artery disease. A second planned Phase 2 trial, designated ASSURE, will include subjects with acute coronary syndrome and coronary artery disease of whom all will be examined with intravascular ultrasound (IVUS). Both the ASSERT and ASSURE studies are chaired by Dr. Steven Nissen, MD, Chairman of the Cleveland Clinic Department of Cardiovascular Medicine and the principal investigator is Dr. Stephen Nicholls, Medical Director of Intravascular Ultrasound at the Cleveland Clinic.\nCardiovascular disease is the leading cause of death in the US and other developed nations costing the American health care system an estimated $448.5 billion in 2008. According to the American Heart Association's Heart Disease & Stroke Statistics 2010 publication, approximately every 25 seconds an American will have a coronary event and approximately every minute, someone will die from such an event. A key underlying cause of cardiovascular disease is atheroscleros...