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Repligen Launches AAV Affinity Resins for Gene Therapy Purification
AVIPure® affinity resins address the market need for high performance and caustic stability WALTHAM, Mass., Feb. 15, 2022 (GLOBE NEWSWIRE) -- Repligen
About this update from Repligen Corporation
[{"type":"text","content":"AVIPure® affinity resins address the market need for high performance and caustic stability\nWALTHAM, Mass., Feb. 15, 2022 (GLOBE NEWSWIRE) -- Repligen Corporation (NASDAQ:RGEN), a life sciences company focused on bioprocessing technology leadership, today announced the commercial launch of three advanced affinity chromatography resins for use in gene therapy manufacturing workflows. The resins – AVIPure® - AAV9, AVIPure® - AAV8, and AVIPure® - AAV2 – were developed by Avitide LLC, a Repligen company, and are specific to the major adeno-associated virus (AAV) gene therapy vectors used today. AAV vectors are the leading platform for gene delivery for the treatment of a variety of human diseases1. Vikas Gupta, Vice President and General Manager, Downstream Bioprocessing and Gene Therapy at Repligen said, “These AVIPure resins are powerful tools in our growing arsenal of unique and differentiated solutions for gene therapy manufacturing. The outstanding performance of these resins, combined with our OPUS® pre-packed columns and ARTeSYN chromatography skids, provide our customers with an unparalleled set of integrated chromatography solutions.” Kevin Isett, President and CEO of Avitide said, “We are so pleased to introduce our AVIPure resins, which directly address the need for more advanced affinity solutions for gene therapy workflows. Caustic stability has been a challenge that these AVIPure resins now overcome, without sacrificing high dynamic binding capacity. We believe customers will benefit from superior process economics, including multi-cycle resin capabilities.” Mr. Isett continued, “We look forward to the commercial rollout of these resins, leveraging our operational and commercial capabilities as part of the Repligen family, as we continue to advance additional products through our unique affinity chromatography development platform.” About Avitide LLC, A Repligen CompanyAvitide LLC, acquired by Repligen in September 2021, is a leading chromatography developer with diverse affinity ligand libraries and best-in-class ligand-to-resin development timelines. The company’s R&D platform develops high-performance customized and broadly commercialized biopharmaceutical purification tools for vaccines, traditional biologics, and more complex advanced therapeutic medicine products, including cell and gene therapies. For more info...