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RenovoRx Announces Publication of Positive Early-Stage Clinical Data in International Peer-Reviewed Journal, The Oncologist®
Published data shows that chemotherapy delivered via TAMP™ with prior chemoradiation in Locally Advanced Pancreatic Cancer (LAPC) observed an Overall Survival
About this update from Renovorx, Inc.
[{"type":"text","content":"Published data shows that chemotherapy delivered via TAMP™ with prior chemoradiation in Locally Advanced Pancreatic Cancer (LAPC) observed an Overall Survival (OS) of 27-months Targeted chemotherapy delivery via TAMP is currently being evaluated in an ongoing Phase III clinical trial in LAPC LOS ALTOS, Calif., July 31, 2024 (GLOBE NEWSWIRE) -- RenovoRx, Inc. (“RenovoRx” or the “Company”) (Nasdaq: RNXT), a clinical-stage biopharmaceutical company developing novel precision oncology therapies based on a local drug-delivery platform, today announced a publication of positive early-stage clinical data relating to RenovoRx’s Trans-Arterial Micro-Perfusion (TAMP) therapy platform in the international peer-reviewed journal, The Oncologist. The scholarly article titled, “Treatment of Locally Advanced Pancreatic Cancer (LAPC) Using Localized Trans-Arterial Micro Perfusion (TAMP) of Gemcitabine: Combined Analysis of RR1 and RR2,” is a publication of early-stage clinical data, primarily procedure safety, overall survival (OS), and evaluation of factors associated with OS, in LAPC patients undergoing TAMP from the foundational studies conducted by the Company. The studies included the intra-arterial administration of gemcitabine utilizing the TAMP read in an early Phase I/II dose escalation safety study (RR1) and acquired data from a post-marketing post-treatment observational registry study (RR2). The lead author, Hassan Hatoum, MD, is an oncologist and hematologist at the University of Oklahoma Health Sciences Center (OUHSC). “These important foundational studies highlight the potential for a meaningful advancement in the standard of care for cancer treatment, with less toxicity and improved outcomes,” said Hassan Hatoum, MD. “These clinical data support that TAMP has the potential to extend OS compared to systemic chemotherapy in difficult-to-treat solid tumors and provide a paradigm-shifting treatment option for patients diagnosed with LAPC.” TAMP utilizes RenovoCath®, the Company’s FDA-cleared drug-delivery device, indicated for temporary vessel occlusion in applications including arteriography, preoperative occlusion, and chemotherapeutic drug infusion. TAMP is currently being evaluated in a Phase III clinical trial investigating intra-arterial delivery of chemotherapy via TAMP for the treatment of LAPC versus the standard of care, sy...