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Aileron Therapeutics and Pulmonary Care Experts To Discuss the Potential Implications of LTI-03 for Idiopathic Pulmonary Fibrosis in Virtual Key Opinion Leader Event
Topline results from Phase 1b study of LTI-03, Aileron’s novel Caveolin-1-related peptide in development for the treatment of idiopathic pulmonary fibrosis,
About this update from Rein Therapeutics, Inc.
[{"type":"text","content":"Topline results from Phase 1b study of LTI-03, Aileron’s novel Caveolin-1-related peptide in development for the treatment of idiopathic pulmonary fibrosis, expected in the second quarter of 2024\nWALTHAM, Mass., Feb. 15, 2024 (GLOBE NEWSWIRE) -- Aileron Therapeutics, Inc. (“Aileron”) (NASDAQ: ALRN), a biopharmaceutical company advancing a novel pipeline of first-in-class medicines to address significant unmet medical needs in orphan pulmonary and fibrosis indications, will host a virtual key opinion leader event today from 4:30 to 5:30 p.m. ET titled “Clinical Perspectives on Treating Idiopathic Pulmonary Fibrosis” featuring pulmonary care experts Fernando J. Martinez, M.D., M.S. from Weill Cornell Medicine; Tejaswini Kulkarni, M.D., M.P.H. from University of Alabama at Birmingham Medicine; and Andreas Günther, M.D. from Agaplesion Evang. Central Hesse Hospital and Justus Liebig University. The event will include presentations by Aileron management followed by a panel discussion with the key opinion leaders on the treatment landscape for idiopathic pulmonary fibrosis (IPF), including the current challenges and significant unmet needs that remain for patients with the disease and the Company’s lead product candidate, LTI-03. A live question-and-answer session will follow. “As practicing clinicians and experts in pulmonary care medicine, these key opinion leaders bring valuable experience to the discussion of LTI-03 as a potential treatment option for patients with IPF,” said Cory Hogaboam, Ph.D., Chief Scientist of Aileron. “While Aileron expects to announce topline data from our Phase 1b study of LTI-03 in the second quarter of this year, we are encouraged by the support of these experts for the work we are doing to address the significant unmet need in this patient population.” IPF is a chronic lung disease characterized by progressive tissue scarring that prevents proper lung function. It is a progressive, fatal, age-associated lung disease affecting approximately 100,000 people in the United States1. IPF typically presents in adults 65 or older and is usually fatal within two to five years after diagnosis2. Aileron’s lead product candidate, LTI-03, is a novel Caveolin-1-related (Cav1) peptide with a dual mechanism targeting both alveolar epithelial cell survival as well as inhibition of profibrotic signaling, whereas approve...