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Inspyr Therapeutics Announces Research Collaboration with NYU Winthrop Hospital
Inspyr Therapeutics Announces Research Collaboration with NYU Winthrop Hospital.
About this update from Rebus Hldgs Inc.
[{"type":"text","content":"\n\n WESTLAKE VILLAGE, Calif., Oct. 04, 2017 (GLOBE NEWSWIRE) -- Inspyr Therapeutics (OTCQB:NSPX), a clinical-stage biotechnology company, announced the initiation of a new investigator-sponsored preclinical study of its proprietary compounds generated through its adenosine receptor modulator (ARM) technology platform. This preclinical study will evaluate adenosine receptor agonists for the management of atherosclerosis, a chronic inflammatory disease of the arteries and the primary cause of heart disease and stroke.\n “Atherosclerosis is caused by a chronic inflammatory response resulting in the hardening and narrowing of arteries and early research has demonstrated the potential of our novel adenosine receptor agonists to have atheroprotective effects,” said Ronald Shazer, M.D., Chief Medical Officer of Inspyr Therapeutics. “Previous research with our adenosine receptor agonists demonstrated increased expression of reverse cholesterol transport proteins in cultured human macrophages, an important mechanism against the development of atherosclerosis. We look forward to learning more about the potential utility of our compounds to treat this prevalent disease and expect to have results in early 2018.” “The majority of cardiovascular events, such as heart attacks and strokes, are caused by atherosclerosis and we need better treatment options for patients, particularly as our population ages,” said Allison B. Reiss, M.D., Head, Inflammation Section of the Winthrop Research Institute, at NYU Winthrop Hospital. “As we look for better options for managing this growing health concern, I am excited to study Inspyr’s adenosine receptor agonists as a potential new treatment option.” Dr. Reiss will be working with a highly specialized interdisciplinary team of physicians and scientists including Dr. Joshua De Leon, Director of Cardiovascular Research, Dr. Steven Carsons, Director of Clinical and Translational Research, and Dr. Lora J. Kasselman, molecular and cellular biologist. About AtherosclerosisAtherosclerosis is a chronic, systemic disease where lipids and fibrous elements build up within the walls of arteries. This progressive disease, caused by a chronic inflammatory response, results in the formation atherosclerotic plaques composed of inflammatory cells, smooth muscle cells, ...