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Rallybio Presents Natural History Study for Fetal and Neonatal Alloimmune Thrombocytopenia at the 65th American Society of Hematology Annual Meeting
-- FNAIT Natural History Study to Inform Frequency of FNAIT Risk in a Broad and Diverse Population of Pregnant Women -- -- Study Designed to Provide a
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[{"type":"text","content":"\n-- FNAIT Natural History Study to Inform Frequency of FNAIT Risk in a Broad and Diverse Population of Pregnant Women --\n\n\n-- Study Designed to Provide a Contemporary Control Dataset to Support a Future Registrational Trial in Pregnant Women --\n\n\n NEW HAVEN, Conn.--(BUSINESS WIRE)--\nRallybio Corporation (Nasdaq: RLYB), a clinical-stage biotechnology company committed to identifying and accelerating the development of life-transforming therapies for patients with severe and rare diseases, today presented details from the Rallybio Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT) natural history study in a poster presentation at the 65th American Society of Hematology (ASH) Annual Meeting, in San Diego, California. The FNAIT natural history study is a prospective, non-interventional, multinational alloimmunization study to determine the frequency of expectant mothers of diverse races and ethnicities at higher FNAIT risk.\n\n\n“There is a significant unmet need to establish routine maternal blood screening to identify women at higher risk of FNAIT and provide a well-tolerated, effective prophylactic treatment. Screening mothers for FNAIT during pregnancy is not routinely performed and currently most at-risk pregnancies are not identified prior to birth,” said Emilie Vander Haar, M.D., Weill Cornell Medicine, New York-Presbyterian Hospital and co-author. “By analogy, the introduction of antenatal screening in Rh disease combined with an effective prophylactic therapy has resulted in the virtual elimination of that disease and is one of the most significant medical advances ever achieved. Achieving the same in FNAIT would have lasting implications for expectant moms and their babies.”\n\n\nPrevious FNAIT studies primarily conducted in Caucasian populations suggest that approximately 2% of expectant women are HPA-1a negative and, therefore, at risk for FNAIT. This FNAIT natural history study is the first prospective study that seeks to characterize risk for FNAIT in a racially and ethnically diverse population of pregnant women.\n\n\nThe study is presently being conducted in the United States and across multiple European countries including Germany, Netherlands, Norway, Sweden, and the United Kingdom. Expectant mothers are screened at gestational weeks 10 to 14, enabling early identification and follow-up of women at high...