Business
New Research in Journal Nature on Gelesis Tech
New Research in Journal Nature on Gelesis Tech.
About this update from Puretech Health Plc
[{"type":"text","content":"\n \n \n \n RNS Number : 8092Q\n PureTech Health PLC\n 01 November 2021\n \n \n \n 1 November 2021\n \n PureTech Health plc\n \n \n PureTech is Pleased to Note Publication in Nature's Scientific Reports Featuring the Gelesis Foundational Biomimetic Platform for Treating Obesity and Conditions Related to Diet-Induced Gut Damage\n \n \n New paper in important scientific journal describes the first superabsorbent hydrogel technology made from naturally derived building blocks designed to address obesity and gut related conditions by emulating compositional and mechanical properties of raw vegetables\n \n \n The newly published data showed that specific mechanical properties (elastic component/firmness) of Gelesis hydrogels were beneficial in protecting gut tissue from toxin damage in an ex-vivo model\n \n \n \n First product based on this platform, Plenity\n \n ®, is now FDA cleared and available by prescription to aid in weight management\n \n \n Gelesis' pipeline includes several other therapeutic product candidates in advanced clinical development to potentially treat a range of indications including diet-induced gut damage\n \n \n \n PureTech Health plc (Nasdaq: PRTC, LSE: PRTC) (\"PureTech\" or the \"Company\"), a clinical-stage biotherapeutics company, noted today that its Founded Entity, Gelesis, Inc. (\"Gelesis\") announced today a publication in Nature's Scientific Reports describing the genesis of the underlying technology and engineering process for Gelesis' non-systemic superabsorbent hydrogels. These new materials were designed to replicate compositional and mechanical properties of raw vegetables, and the paper describes their therapeutic approach for weight management as well as possible future solutions for other gut-related conditions.\n \n \n Vegetable consumption is a fundamental part of many dietary interventions. Vegetables occupy volume in the stomach, reducing the caloric density of a meal, and their features are known to enhance satiety. Yet in the treatment of obesity and other related conditions like diabetes or gut-related diseases, nutritional and behavioral modifications are often difficult to implement and maintain. Gelesis thus engineered a novel, cellulose-based superabsorbent hydrogel platform designed to mimic many of the properties of raw vegetables. While not a replacement for vegetables as...