Result of Equity Issue

Proteome Sciences PLC 04 June 2004 NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION IN, OR INTO, THE UNITED STATES, CANADA, AUSTRALIA OR JAPAN Proteome Sciences plc Results of Placing Proteome Sciences plc is pleased to announce that the 1,848,739 new ordinary shares have been successfully placed at 119 pence per share. The placing is conditional on Admission and dealings are expected to commence on 9 June 2004. Enquiries: Proteome Sciences plc Christopher Pearce, Chief Executive 01932 865065 James Malthouse, Finance Director Dresdner Kleinwort Wasserstein Michael Covington 020 7623 8000 This announcement has been issued by Proteome Sciences and is the sole responsibility of Proteome Sciences. This announcement is for information purposes only and does not constitute an offer to sell or issue any securities or a solicitation of an offer to buy or acquire any securities or investment advice in any jurisdiction including, without limitation, the United Kingdom, the United States, Canada, Australia or Japan. The Placing Shares have not been and will not be registered under the US Securities Act of 1933 (the 'Securities Act') and may not be offered or sold within the United States absent registration or an exemption from registration. No public offering of securities will be made in the United States. Dresdner Kleinwort Wasserstein Limited ('DrKW') and Dresdner Kleinwort Wasserstein Securities Limited DrKWS, which are authorised and regulated by the Financial Services Authority under the Financial Services and Markets Act 2000 ('FSMA'), are acting for Proteome Sciences and for no one else in connection with the Placing and will not be responsible to anyone other than Proteome Sciences for providing the protections afforded to clients of DrKW and DrKWS, nor for providing advice in relation to the Placing or any other matter referred to in this announcement. Neither this document nor any copy of it may be taken, transmitted or distributed, directly or indirectly, in or into the United States, Canada, Australia or Japan or in any jurisdiction in which such transmission or distribution is unlawful. Any failure to comply with this restriction may constitute a violation of US, Canadian, Australian or Japanese securities laws or the securities laws of other states as the case may be. This information is provided by RNS The company news service from the London Stock Exchange