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Propanc Biopharma’s Joint Research Partnership with the Universities of Jaén and Granada Enters 13th Year
MELBOURNE, Australia--(BUSINESS WIRE)-- Propanc Biopharma, Inc. (OTCQB: PPCB) (“Propanc” or the “Company”), a biopharmaceutical company developing novel
About this update from Propanc Biopharma, Inc.
[{"type":"text","content":" MELBOURNE, Australia--(BUSINESS WIRE)--\nPropanc Biopharma, Inc. (OTCQB: PPCB) (“Propanc” or the “Company”), a biopharmaceutical company developing novel cancer treatments for patients suffering from recurring and metastatic cancer, today announced that the joint research partnership with the Universities of Jaén and Granada, Spain, is entering its thirteenth year since their collaboration began in 2009. The research partnership is led by Professor Macarena Perán, Ph.D., from Jaén University, supported by Professor Juan Marchal M.D., Ph.D., at the University of Granada, and Dr. Julian Kenyon M.B.Ch.B., M.D., Chief Scientific Officer at Propanc Biopharma. The enduring partnership with the Universities, as well as working with contract research organizations (CRO’s) and contract manufacturing organizations (CMO’s) has led to the Company’s lead product candidate, PRP, advance towards a First-In-Human clinical study and plans to develop a backup clinical candidate from the POP1 joint research and drug discovery program also underway.\n\nSince the establishment of the joint research partnership, the program has supported the advancement of the Company’s drug development activities from discovery to clinical stage and elucidated the anti-cancer effects of proenzymes, in particular against cancer stem cells (CSCs), the changes in gene expression relating to oncogenesis and metastasis in CSCs, thus inhibiting cancer spread, whilst exerting effects on other tumor elements in the tumor microenvironment, resulting in prevention of tumor niche formation. Fundamentally demonstrating how proenzymes exert potent anti-tumor, anti-cancer and anti-metastatic effects. The program has produced 5 scientific research publications and multiple patentable discoveries, leading to an IP portfolio consisting of 65 patents filed in major global jurisdictions.\n\n“The joint research partnership with the Universities of Jaén and Granada has been critical for the advancement of our drug development program at Propanc Biopharma,” said Dr. Julian Kenyon. “I am grateful for their tireless efforts, led by Professor Perán, supported by Professor Marchal, whose capabilities and expertise in the field are impressive. As we advance towards our First-In-Human study in advanced cancer patients for our lead product candidate, PRP, I am excited about our ongoing efforts...