Business
Propanc Biopharma Offers a Novel Way to Stop Cancer
Differentiation therapy has distinct advantages over Conventional Therapeutic Strategies MELBOURNE, Australia--(BUSINESS WIRE)-- Propanc Biopharma, Inc.
About this update from Propanc Biopharma, Inc.
[{"type":"text","content":"\nDifferentiation therapy has distinct advantages over Conventional Therapeutic Strategies\n\n MELBOURNE, Australia--(BUSINESS WIRE)--\nPropanc Biopharma, Inc. (OTCQB: PPCB) (“Propanc” or the “Company”), a biopharmaceutical company developing novel cancer treatments for patients suffering from recurring and metastatic cancer, today announced a novel way to stop cancer by inducing a process called “cell differentiation”. Known as differentiation therapy, the key objective is to convince malignant cells to stop proliferating and return to do their work as a specific cell type. There are advantages of differentiation therapy over conventional therapeutic strategies. Differentiation therapy does not target cell death, so healthy cells within the patient will not be compromised, unlike chemotherapeutic drugs or gamma irradiation.\n\nFirstly, most people understand that cancer develops when cells in the body start to divide rapidly and uncontrollably, with an ability to migrate from one location and spread to distant sites. A cell becomes cancerous when it becomes undifferentiated. Essentially, the cell forgets to do its job and invests all its energy into proliferating. Unlike normal cells, cancer cells multiply, but do not differentiate. Therefore, most common cancer therapies work by taking advantage of the uncontrolled proliferation of cancer cells and kill these cells by targeting the cell division machinery. These therapies are effective, but also affect healthy cells, particularly those with a high rate of cell turnover, thus inducing undesirable effects.\n\nConversely, differentiation therapy induces cancer cells into the pathway of terminal differentiation (fully differentiated) and eventual senescence (i.e., loss of a cell’s division and growth). Differentiation therapy acts not only against cancer cells, but interestingly can turn cancer stem cells (undifferentiated cells) towards completely differentiated (i.e., normal) cells.\n\nBut what lesson can we learn from our own body? Are there any natural elements within our organism that could help us fight against cancer? As a matter of fact, yes, there are enzymes, which are natural proteins that stimulate and accelerate biological reactions in the body. Particularly enzymes secreted by the pancreas that are essential for the digestion of proteins and fats. More than 100 years...