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Precision BioSciences Announces Data Presentation on Effective Cell Dose and Functional Attributes of CD19 Allogeneic CAR T, Azer-Cel, at the Upcoming 2022 American Society of Hematology (ASH) Annual Meeting
DURHAM, N.C.--(BUSINESS WIRE)-- Precision BioSciences, Inc. (Nasdaq: DTIL), a clinical stage gene editing company developing ARCUS®-based ex vivo allogeneic
About this update from Precision Biosciences, Inc.
[{"type":"text","content":" DURHAM, N.C.--(BUSINESS WIRE)--\nPrecision BioSciences, Inc. (Nasdaq: DTIL), a clinical stage gene editing company developing ARCUS®-based ex vivo allogeneic CAR T and in vivo gene editing therapies, today announced that an abstract on the effective cell dose and functional attributes of the company’s lead CD19 candidate, Azercabtagene Zapreleucel (azer-cel) was accepted for poster presentation at the 64th American Society of Hematology (ASH) Annual Meeting and Exposition, being held December 10-13, 2022 in New Orleans, Louisiana. Precision is currently evaluating azer-cel in a Phase 1/2a clinical trial of adult subjects with relapsed or refractory (R/R) non-Hodgkin lymphoma (NHL) who relapsed following treatment with an autologous CAR T.\n\n“We look forward to seeing this data presented at the ASH meeting and highlighting the differentiated product cellular attributes including product composition and cell doses that contribute to optimized efficacy and safety of azer-cel. This is the first analysis of an allogeneic CD19 CAR T product composition to demonstrate that strategies to maximize naïve cell phenotype may lead to improved safety and efficacy of an allogenic CAR T therapy,” said Alan List, M.D., Chief Medical Officer of Precision BioSciences.\n\nPoster Presentation Details:\n\nTitle: Effective Cell Dose and Functional Attributes of Azercabtagene Zapreleucel (azer-cel; PBCAR0191) Associate with Allogeneic CAR T-Cell Safety and Efficacy in Patients with Relapsed/Refractory B-Cell Lymphoma\nFirst Author: Caron A. Jacobson, M.D., Dana Farber Cancer Institute\nPoster Session: 704. Cellular Immunotherapies: Early Phase and Investigational Therapies: Poster I\nAbstract #: 2005\nDate/Time: Saturday, December 10, 2022, 5:30 PM – 7: 30 PM ET\nLocation: Ernest N. Morial Convention Center, Hall D\n\nThe abstract accepted for poster presentation is now available at www.hematology.org.\n\nAbout Precision BioSciences, Inc.\n\nPrecision BioSciences, Inc. is a clinical stage biotechnology company dedicated to improving life (DTIL) with its novel and proprietary ARCUS® genome editing platform. ARCUS is a highly precise and versatile genome editing platform that was designed with therapeutic safety, delivery, and control in mind. Using ARCUS, the company’s pipeline consists of multiple ex vivo “off-the-shelf” CAR T immunotherapy clinical ...