Business
PYC to present and exhibit at SITC Annual Meeting
PYC to present and exhibit at SITC Annual Meeting.
About this update from Physiomics Plc
[{"type":"text","content":"\n \n \n \n 9 November 2022\n \n \n \n \n \n \n Physiomics plc\n \n \n (\"Physiomics\") or (\"the Company\")\n \n \n \n \n \n \n \n \n Conference presentation\n \n \n \n \n \n \n \n \n \n Physiomics to present and exhibit at SITC Annual Meeting\n \n \n \n \n \n \n Physiomics plc (AIM: PYC),\n a provider of technology-based solutions to predict the effects of cancer treatment regimens for the biopharma industry,\n is pleased to announce that it is participating in the 37th Annual Meeting of the Society for Immunotherapy of Cancer (\"SITC\"), being held this week on 8-12 November 2022 in Boston, USA.\n \n \n \n \n \n The Company will be presenting an original poster\n entitled: \"Establishing the preclinical PKPD relationship for NM32-2668 a ROR1 targeting T cell engager\". Physiomics is co-authoring the poster with client Numab Therapeutics (\"Numab\") whose investigational drug NM32 is currently in IND-enabling studies. NM32 is a tri-specific anti-ROR1/CD3/HSA antibody based on Numab's scMATCH3 format which induces T cell-mediated lysis of tumours expressing Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1).\n \n \n \n \n \n The pharmacokinetic and pharcodynamic models developed during this work provide quantitative confirmation of the mechanism of action of NM32-2668. The model will support the establishment of a first-in-human starting dose and a strategy to enable clinical effective dose selection.\n \n \n \n \n \n The poster (Abstract #1293) will be presented on 10 November from 0900-1900 EST, with the presenting authors attending at lunch (1140-1310) and during the poster reception (1930-2100). The abstract is now available in Journal for ImmunoTherapy of Cancer's November 2022 Issue Supplement, which can be accessed at:\n \n \n https://jitc.bmj.com/content/10/Suppl_2/A1341\n \n \n . A copy of the poster will be posted on Physiomics' website at 0900 EST (1400 GMT) on the same day at:\n \n \n https://www.physiomics.co.uk/resources\n \n \n .\n \n \n \n \n \n The Company will have substantial presence at the conference comprising both scientific and business development team members and will also host a stand in the main conference meeting hall (booth #236). If you'd like to meet the team at our booth please drop by or use this link to book a meeting:...